Article
Oncology
Kristen A. McGovern, William J. Durham, Traver J. Wright, E. Lichar Dillon, Kathleen M. Randolph, Christopher P. Danesi, Randall J. Urban, Melinda Sheffield-Moore
Summary: This study found that testosterone therapy in cancer patients did not improve cancer-related fatigue symptoms, inflammatory markers, or health-related quality of life.
Article
Oncology
Danielle E. J. Starreveld, Laurien A. Daniels, Jacobien M. Kieffer, Heiddis B. Valdimarsdottir, Jessie de Geus, Mirthe Lanfermeijer, Eus J. W. van Someren, G. Esther A. Habers, Jos A. Bosch, Cecile P. M. Janus, Dick Johan van Spronsen, Roel J. de Weijer, Erik W. A. Marijt, Eva de Jongh, Josee M. Zijlstra, Lara H. Bohmer, Margreet Houmes, Marie Jose Kersten, Catharina M. Korse, Huub H. van Rossum, William H. Redd, Susan K. Lutgendorf, Sonia Ancoli-Israel, Flora E. van Leeuwen, Eveline M. A. Bleiker
Summary: This study aimed to evaluate the short- and long-term effects of light therapy on fatigue and other health outcomes in survivors of cancer-related fatigue. The results showed that bright white light and dim white light did not significantly differ in reducing fatigue, but both interventions led to improvements in fatigue levels, depression, sleep quality, and quality of life. Light therapy did not affect circadian rhythms in this study.
Article
Surgery
Filipe Basile, Thais S. Oliveira
Summary: Early exercise after breast augmentation surgery does not increase complications or reoperation rates, and does not cause a reduction in scar quality. In addition, patient-reported outcomes show improvement in the exercise group.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Oncology
Sriram Yennurajalingam, Ahsan Azhar, Zhanni Lu, Ashley J. Rodriguez, Adrienne B. Arechiga, Maria Guerra-Sanchez, Penny Stanton, Clark R. Andersen, Diana L. Urbauer, Eduardo Bruera
Summary: This study aimed to evaluate the effects of an open-labeled placebo compared with a waitlist control in reducing cancer-related fatigue. The results showed that after 1 week of treatment, the open-labeled placebo was effective in reducing fatigue symptoms in patients with advanced cancer, and this improvement was maintained for 4 weeks.
Article
Oncology
Min Kyeong Jang, Jeehee Han, Sung Hae Kim, Yun Hee Ko, Soo Yeon Kim, Sue Kim
Summary: The study investigated the effects of a 15-month intervention on fatigue and fatigability in breast cancer survivors, exploring their relationships with anxiety, depression, sleep disturbance, and endocrine symptoms. Results showed different correlations between fatigue and fatigability after the exercise intervention, with only cognitive/mood fatigue score and depression significantly associated in the experimental group.
Article
Clinical Neurology
Laura J. Connolly, Shantha M. W. Rajaratnam, Jade M. Murray, Gershon Spitz, Steven W. Lockley, Jennie L. Ponsford
Summary: This study found that in-home dynamic light therapy can potentially alleviate fatigue, sleep disturbances, daytime sleepiness and improve participation in daily productive activities for individuals with acquired brain injury.
Article
Respiratory System
Natalia Febrini Passos, Patricia D. Freitas, Regina Maria Carvalho-Pinto, Alberto Cukier, Celso R. F. Carvalho
Summary: This study aimed to evaluate the effect of a behavioral intervention to increase physical activity on sleep quality in adults with asthma. The results showed that the intervention group had increased physical activity levels, improved sleep quality and asthma symptoms, and reduced anxiety symptoms.
Article
Oncology
Kyungsun Han, Mikyung Kim, Eun-Jung Kim, Yeon-Cheol Park, Ojin Kwon, Ae-Ran Kim, Hyo-Ju Park, Yang-Chun Park, Jung Hyo Cho, Joo-Hee Kim, Jun-Hwan Lee
Summary: The study confirmed the efficacy and safety of moxibustion for CRF compared to usual care, and it also found a prolonged treatment effect during the 4 weeks of follow-up period.
Article
Health Care Sciences & Services
Ivan H. C. Wu, Diwakar D. Balachandran, Saadia A. Faiz, Lara Bashoura, Carmen P. Escalante, Ellen F. Manzullo
Summary: This study characterized cancer-related fatigue and sleep architecture among cancer patients. The results showed that patients often experienced fatigue, sleep disturbances, and excessive daytime sleepiness. A majority of patients referred for sleep consultation were diagnosed with obstructive sleep apnea.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Multidisciplinary Sciences
Jennifer L. Huberty, Jeni Green, Megan E. Puzia, Linda Larkey, Breanne Laird, Ana-Maria Vranceanu, Robert Vlisides-Henry, Michael R. Irwin
Summary: This study demonstrates that the Calm app can effectively reduce fatigue, daytime sleepiness, and pre-sleep arousal in adults with sleep disturbance, and has a positive impact on improving sleep quality.
Article
Clinical Neurology
Gavin Brupbacher, Thea Zander-Schellenberg, Doris Straus, Hildburg Porschke, Denis Infanger, Markus Gerber, Roland von Kanel, Arno Schmidt-Trucksaess
Summary: This study investigated the effects of a single bout of aerobic exercise performed after 2:00 pm on subsequent night's sleep in patients with depression. While the exercise did not affect sleep efficiency, it had a strong beneficial effect on mood states, including depressiveness.
Article
Clinical Neurology
Gavin Brupbacher, Thea Zander-Schellenberg, Doris Straus, Hildburg Porschke, Denis Infangerl, Markus Gerber, Roland von Kaenel, Arno Schmidt-Trucksaess
Summary: The study aimed to investigate the effects of a single bout of aerobic exercise on sleep in patients with depression. The results showed that aerobic exercise had no effect on sleep efficiency but had a strong beneficial effect on mood and did not increase adverse outcomes. These findings suggest that exercise after 02:00 pm is not detrimental for sleep, contrary to sleep hygiene recommendations.
Article
Nursing
Xiaole He, Marques Shek Nam Ng, Kai Chow Choi, Winnie Kwok Wei So
Summary: This study examined the effects of a culturally specific dance intervention on reducing the symptoms of fatigue, sleep disturbance, and depression in Chinese women with breast cancer receiving adjuvant chemotherapy. The results showed that the dance intervention group reported less severe symptoms, a lower incidence of the symptom cluster, and improved quality of life compared to the control group. These findings suggest that dance intervention may be a promising method for managing the fatigue-sleep disturbance-depression symptom cluster and promoting the quality of life in Chinese women with breast cancer undergoing adjuvant chemotherapy.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Medicine, General & Internal
Afnan Essam Masoud, Afaf Ahmed Mohamed Shaheen, Maha Fahad Algabbani, Enas AlEisa, Amani AlKofide
Summary: The study aims to examine the effectiveness of exergaming in reducing Cancer Related Fatigue (CRF) and improving functional capacity/endurance and promote physical activity (PA) in children with acute lymphoblastic leukemia. The results show that exergaming effectively reduces CRF and promotes functional capacity/endurance and PA in children undergoing chemotherapy, providing an alternative treatment modality to decrease the healthcare load.
ANNALS OF MEDICINE
(2023)
Article
Oncology
Melanie P. J. Schellekens, Fieke Z. Bruggeman-Everts, Marije D. J. Wolvers, Miriam M. R. Vollenbroek-Hutten, Marije L. van der Lee
Summary: This study explored whether baseline characteristics moderated the effect of web-based mindfulness-based cognitive therapy (eMBCT) on fatigue in patients suffering from chronic cancer-related fatigue (CCRF). The findings indicate that baseline fatigue severity and fatigue catastrophizing can influence the intervention effect, highlighting the potential benefit of personalized treatment.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Adam Yan, Kaitlyn Howden, Alyson L. Mahar, Ian Scott, Camille Glidden, Julie Deleemans, Karine Chalifour, Geoff Eaton, Abha Gupta, James M. Bolton, Sheila N. Garland, Sapna Oberoi
Summary: This study evaluated the impact of the COVID-19 pandemic on adolescent and young adult cancer survivors. The findings showed that survivors reported high levels of psychological distress, insomnia, and loneliness. Factors such as income, employment status, and the pandemic's influence on finances were associated with these adverse effects. Additionally, the pandemic negatively affected employment, finances, physical activity, cancer care, and substance use for a significant portion of the survivors.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Clinical Neurology
Cassian J. Duthie, Claire Cameron, Kelby Smith-Han, Lutz Beckert, Shenyll Delpachitra, Sheila N. Garland, Bryn Sparks, Erik Wibowo
Summary: This study aims to investigate factors affecting the sleep of medical students and how they currently manage their sleep. The results show that depressive symptoms and sleep hygiene are associated with insomnia symptoms. Commonly endorsed strategies for sleep management include regular exercise, consistent sleep-wake time, and limiting caffeine intake. However, few students are willing to seek medical help or take medication for sleep issues.
BEHAVIORAL SLEEP MEDICINE
(2023)
Article
Oncology
Xiaotong Li, Ting Bao, Sheila N. Garland, Susan Q. Li, Jennifer Yu, Yuelin Li, Jun J. Mao
Summary: This study found that pre-treatment outcome expectancy was positively associated with insomnia improvement in cancer survivors receiving acupuncture, but not in those receiving CBT-I.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Oncology
Dhasni Muthumuni, Ian Scott, Harvey Max Chochinov, Alyson L. Mahar, Sheila N. Garland, Fiona Schulte, Pascal Lambert, Lisa Lix, Allan Garland, Sapna Oberoi
Summary: This study aimed to determine the feasibility and acceptability of a virtual Coping with Brain Fog intervention among young adults with cancer and explore its effects on cognitive functioning and psychological distress. The results showed that the intervention was feasible and well-accepted, and participants experienced improvements in cognitive functioning and psychological distress.
JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY
(2023)
Article
Oncology
Athina Spiropoulos, Julie Deleemans, Sara Beattie, Linda E. Carlson
Summary: Mothers with cancer struggle to balance their roles as parents and patients, leading to feelings of shame and guilt. This study explores how these mothers cope with multiple role demands and how their identities as women and individuals with disabilities influence their coping strategies. The Role Coping as a Mother with Cancer (RCMC) model is developed to understand the complex nature of motherhood and provide insights for further research and clinical care.
Article
Clinical Neurology
Samlau Kutana, Jun J. Mao, Sheila. N. Garland
SLEEP MEDICINE CLINICS
(2023)
Article
Clinical Neurology
Samlau Kutana, Sheila N. Garland, Eric S. Zhou
Summary: This article discusses the existing research on internet-delivered cognitive behavioral therapy for insomnia (iCBT-I) and identifies three critical gaps in the next wave of clinical trials. It focuses on iCBT-I interventions with automated delivery of clinical content, rather than CBT-I-based telemedicine interventions involving synchronous clinician participation.
CURRENT SLEEP MEDICINE REPORTS
(2023)
Article
Oncology
Linda E. Carlson, Nofisat Ismaila, Elizabeth L. Addington, Gary N. Asher, Chloe Atreya, Lynda G. Balneaves, Joke Bradt, Nina Fuller-Shavel, Joseph Goodman, Caroline J. Hoffman, Alissa Huston, Ashwin Mehta, Channing J. Paller, Kimberly Richardson, Dugald Seely, Chelsea J. Siwik, Jennifer S. Temel, Julia H. Rowland
Summary: This article aims to provide evidence-based recommendations to healthcare providers on integrative approaches to managing anxiety and depression symptoms in adults living with cancer.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Health Care Sciences & Services
Joshua Tulk, Amanda Wurz, Sharon H. J. Hou, Jacqueline Bender, Fiona S. M. Schulte, Geoff Eaton, Karine Chalifour, Sheila N. Garland
Summary: This study explores the impact of rurality and social support on distress and quality of life in young adults with cancer in Canada. It finds that rural YA cancer survivors experience higher distress and poorer physical health-related quality of life compared to urban survivors, but similar levels of mental-health-related quality of life. Different types of social support have varying levels of association with distress depending on a participant's geography.
JOURNAL OF RURAL HEALTH
(2023)
Article
Clinical Neurology
Sheila N. Garland, Joshua Tulk, Riley Cotter, Eric S. Zhou, Lauren C. Daniel, Fiona S. M. Schulte, Jacqueline L. Bender, Karine Chalifour, Geoff Eaton
Summary: This study describes sleep issues in young adults and analyzes potential demographic and clinical characteristics related to sleep quality. The results show that psychological distress is associated with worse sleep quality and sleep medication use in young adult cancer survivors. This may be a possible target for future research and intervention to promote long-term function and recovery.
Article
Oncology
Rachel Lee, Jennifer Donnan, Nick Harris, Sheila Garland
Summary: This study investigated the use and perceived effects of cannabis as a sleep aid in Canadian cancer survivors. The findings suggest that cannabis can help cancer survivors relax, reduce the time it takes to fall asleep, decrease nocturnal awakenings, and improve sleep quality. Further research is needed to examine the actual efficacy of cannabis as a sleep aid.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Oncology
Fiona S. M. Schulte, Sharon H. J. Hou, Jacqueline L. Bender, Joshua Tulk, Amanda Wurz, Anika Petrella, Catherine M. Sabiston, Norma D'Agostino, Karine Chalifour, Geoff Eaton, Sheila N. Garland
Summary: Adolescents and young adults diagnosed with cancer face challenges in achieving employment and independent living compared to the general population. These challenges may have significant implications for their long-term financial and quality of life outcomes.
Article
Oncology
Linda E. Carlson, Nofisat Ismaila, Elizabeth L. Addington, Gary N. Asher, Joke Bradt, Ashwin Mehta, Julia H. Rowland, SIO ASCO Expert Panel
JCO ONCOLOGY PRACTICE
(2023)
Article
Health Care Sciences & Services
Michaela Patton, Linda E. Carlson, Melanie Noel, Tonya Palermo, Victoria Forster, Sara Cho, Fiona Schulte
Summary: This study aims to test the feasibility and acceptability of a web-based cognitive behavioral treatment for chronic pain (WebMAP) in childhood cancer survivors and their parents. It also aims to assess the effects of WebMAP on activity limitations, pain intensity, depression and anxiety symptoms, and sleep disturbances. The study will further evaluate the impact of WebMAP on parental responses to their child's pain and parent pain catastrophizing.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Cardiac & Cardiovascular Systems
Kaitlyn Paltzat, Sara Scott, Kirnvir K. Dhaliwal, Terry Saunders-Smith, Braden J. Manns, Tavis Campbell, Noah Ivers, Raj Pannu, David J. T. Campbell
Summary: This study qualitatively explored participants' perspectives on a self-management education support program and found positive impacts in terms of empowerment, acceptability, and suggestions for improvement. The study highlighted key strategies to promote patient engagement and self-management behaviors.
Article
Medicine, Research & Experimental
Hongjin Li, Judith M. Schlaeger, Crystal L. Patil, Oana Danciu, Zhengjia Chen, Natalie Lif, Shuang Gao, Ardith Z. Doorenbos
Summary: Nearly 94% of breast cancer survivors experience symptoms or side effects during or after endocrine therapy, and acupuncture offers a comprehensive solution to address these issues. However, medically underserved breast cancer survivors often lack access to acupuncture. To promote equal access and evidence-based treatment, a randomized controlled trial is being conducted to investigate the effectiveness of acupuncture for symptom management among this population.
CONTEMPORARY CLINICAL TRIALS
(2024)
Article
Medicine, Research & Experimental
JoAnn M. Sperl-Hillen, Jacob L. Haapala, Steven P. Dehmer, Lilian N. Chumba, Heidi L. Ekstrom, Anjali R. Truitt, Stephen E. Asche, Ann M. Werner, Dan J. Rehrauer, Melissa A. Pankonin, Pamala A. Pawloski, Patrick J. O'Connor
Summary: This article describes the original and adapted protocols of a randomized trial to improve medication adherence for cardiometabolic conditions. Protocol adaptation became imperative in response to major implementation challenges.
CONTEMPORARY CLINICAL TRIALS
(2024)
Article
Medicine, Research & Experimental
Connor Celum, Bethany Jablonski Horton, Mark Conaway
Summary: This paper proposes a phase-I clinical trial design that uses ordinal toxicity to locate group-specific doses. The proposed method avoids dose-reversals and is compared with two other methods through simulations.
CONTEMPORARY CLINICAL TRIALS
(2024)
Article
Medicine, Research & Experimental
Tanya Knutzen, Eileen Bulger, Matt Iles-Shih, Alexandra Hernandez, Allison Engstrom, Lauren Whiteside, Navneet Birk, Khadija Abu, Jake Shoyer, Cristina Conde, Paige Ryan, Jin Wang, Joan Russo, Patrick Heagerty, Larry Palinkas, Douglas Zatzick
Summary: This study aims to investigate how trauma centers in the US can effectively conduct mental health screening, intervention, and referral services to help injured patients recover. The study will randomly assign patients to different intervention groups and compare the impact of different interventions on PTSD symptoms and emergency department/inpatient utilization.
CONTEMPORARY CLINICAL TRIALS
(2024)