Journal
JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
Volume 222, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jenvrad.2020.106357
Keywords
Depleted uranium; Aerosol; Biological effects; Treatments
Categories
Funding
- National Natural Science Fund [81972972, 19QNP006, 2019-JCJQ-JJ-019]
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Depleted uranium (DU) is primarily used for DU bombs and DU tanks in the military. Aerosol inhalation is considered the primary route of DU exposure. Although laboratory tests have confirmed that inhalation of DU aerosol can cause lung, kidney, and other organ damage, epidemiological studies have found no conclusive evidence that persons in areas with prolonged exposure to DU-containing bombs are affected. After the body inhaled DU aerosols, we first clear the insoluble DU through whole-lung lavage (WLL). Then we eliminate the soluble uranium by the chelating agent. Besides, reducing DU damage to tissues and cells through drugs is also an important treatment method. In future research, emphasis should be placed on the damage mechanism of DU aerosol, the laboratory and clinical research of DU chelating agents, the research on the combination of DU chelating agent and WLL, and the research and development of new drugs to prevent DU damage.
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