Septin 7 is a centrosomal protein that ensures S phase entry and microtubule nucleation by maintaining the abundance of p150 glued

7-hydroxy-staurosporine, UCN-01, induces DNA damage response, and autophagy in human osteosarcoma U2-OS cells

(2018) Wei-Chih Lien et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chloroquine inhibits human retina pigmented epithelial cell growth and microtubule nucleation by downregulating p150glued

(2018) Ting-Yu Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells

(2017) Chia-Yih Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

SEPT12 phosphorylation results in loss of the septin ring/sperm annulus, defective sperm motility and poor male fertility

(2017) Yi-Ru Shen et al.   PLoS Genetics

SEPT7 overexpression inhibits glioma cell migration by targeting the actin cytoskeleton pathway

(2016) MINGSHAN HOU et al.   ONCOLOGY REPORTS

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis

(2016) Megha Abbey et al.   Scientific Reports

Hook2, a microtubule-binding protein, interacts with Par6α and controls centrosome orientation during polarized cell migration

(2016) Emilie Pallesi-Pocachard et al.   Scientific Reports

Cell Cycle-Dependent Localization of Dynactin Subunit p150gluedat Centrosome

(2015) Ting-Yu Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Centrosome and Its Duplication Cycle

(2015) Jingyan Fu et al.   Cold Spring Harbor Perspectives in Biology

Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells

(2015) T-Y Chen et al.   Oncogenesis

Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

(2014) Lee Dolat et al.   JOURNAL OF CELL BIOLOGY

HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes

(2014) K. Li et al.   JOURNAL OF CELL SCIENCE

PCP and Septins Compartmentalize Cortical Actomyosin to Direct Collective Cell Movement

(2014) A. Shindo et al.   SCIENCE

Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis

(2014) Manoj B. Menon et al.   PLoS Genetics

The human septin7 and the yeast CDC10 septin prevent Bax and copper mediated cell death in yeast

(2013) Avital Horowitz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length

(2013) R. Ghossoub et al.   JOURNAL OF CELL SCIENCE

Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome

(2013) Olga N. Zhapparova et al.   MOLECULAR BIOLOGY OF THE CELL

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

(2013) Natsumi Ageta-Ishihara et al.   Nature Communications

Septin-Driven Coordination of Actin and Microtubule Remodeling Regulates the Collateral Branching of Axons

(2012) Jianli Hu et al.   CURRENT BIOLOGY

Steroidogenic Factor 1 (NR5A1) Maintains Centrosome Homeostasis in Steroidogenic Cells by Restricting Centrosomal DNA-Dependent Protein Kinase Activation

(2012) Chia-Yih Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Septin roles in tumorigenesis

(2011) Diana Connolly et al.   BIOLOGICAL CHEMISTRY

Steroidogenic Factor 1 (NR5A1) resides in centrosomes and maintains genomic stability by controlling centrosome homeostasis

(2011) P-Y Lai et al.   CELL DEATH AND DIFFERENTIATION

Orientation and function of the nuclear–centrosomal axis during cell migration

(2011) GW Gant Luxton et al.   CURRENT OPINION IN CELL BIOLOGY

Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis

(2011) Lidia Hurtado et al.   JOURNAL OF CELL BIOLOGY

Centrosomal Localization of Cyclin E-Cdk2 Is Required for Initiation of DNA Synthesis

(2010) Rebecca L. Ferguson et al.   CURRENT BIOLOGY

The Dynactin Complex Maintains the Integrity of Metaphasic Centrosomes to Ensure Transition to Anaphase

(2010) Yuko Ozaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Septins: molecular partitioning and the generation of cellular asymmetry

(2009) Michael A McMurray et al.   Cell Division

The septin family of GTPases: architecture and dynamics

(2008) Christine S. Weirich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY