Exploring substituent diversity of deoxynojirimycin–triazole hybrid iminosugars: Discovery of potent glucosidase inhibitors

Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition

(2019) Macarena Martínez-Bailén et al.   BIOORGANIC CHEMISTRY

Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes

(2019) Xhenti Ferhati et al.   BIOORGANIC CHEMISTRY

Chemical synthesis and preliminary biological evaluation of C-6-O-methyl-1-deoxynojirimycin as a potent α-glucosidase inhibitor

(2019) Lin Wang et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Cluster glycosides and heteroglycoclusters presented in alternative arrangements

(2018) Andreza S. Figueredo et al.   TETRAHEDRON LETTERS

Investigation of original multivalent iminosugars as pharmacological chaperones for the treatment of Gaucher disease

(2016) Eugénie Laigre et al.   CARBOHYDRATE RESEARCH

Cu-Catalyzed Click Reaction in Carbohydrate Chemistry

(2016) Vinod K. Tiwari et al.   CHEMICAL REVIEWS

Design, synthesis and biological evaluation of small molecules as potent glucosidase inhibitors

(2015) Santanu Hati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Review: Miglitol has potential as a therapeutic drug against obesity

(2015) Satoru Sugimoto et al.   Nutrition & Metabolism

Exploiting the Hydrophobic Terrain in Fucosidases with Aryl-Substituted Pyrrolidine Iminosugars

(2014) Audrey Hottin et al.   CHEMBIOCHEM

The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Valency, Peripheral Ligand Structure, and Topology with Cyclodextrin-Based Iminosugar Click Clusters

(2013) Camille Decroocq et al.   CHEMBIOCHEM

Development of α-glucosidase inhibitors by room temperature C–C cross couplings of quinazolinones

(2013) Ramesh Garlapati et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Mulberry Leaf Extract Reduces Postprandial Hyperglycemia with Few Side Effects by Inhibiting α-Glucosidase in Normal Rats

(2011) Gyo-Nam Kim et al.   JOURNAL OF MEDICINAL FOOD

Amphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher Cells

(2011) Jennifer D. Diot et al.   JOURNAL OF ORGANIC CHEMISTRY

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain

(2011) Nicolas Ardes-Guisot et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

(2010) Philippe Compain et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyperglycemic Crises in Adult Patients With Diabetes: Response to Kitabchi et al.

(2009) K. Yasuda et al.   DIABETES CARE

Validation of the Copper(I)-Catalyzed Azide−Alkyne Coupling in Ionic Liquids. Synthesis of a Triazole-LinkedC-Disaccharide as a Case Study

(2008) Alberto Marra et al.   JOURNAL OF ORGANIC CHEMISTRY

Multivalent iminosugars to modulate affinity and selectivity for glycosidases

(2008) Jennifer Diot et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Large-Scale Synthesis of the Glucosylceramide Synthase InhibitorN-[5-(Adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin

(2008) Tom Wennekes et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT