The impact of single nucleotide polymorphisms in ADORA2A and ADORA3 genes on the early response to methotrexate and presence of therapy side effects in children with juvenile idiopathic arthritis: Results of a preliminary study

Baseline adenosine receptor mRNA expression in blood as predictor of response to methotrexate therapy in patients with rheumatoid arthritis

(2019) Ankita Singh et al.   RHEUMATOLOGY INTERNATIONAL

Methotrexate in juvenile idiopathic arthritis: advice and recommendations from the MARAJIA expert consensus meeting

(2018) Giovanna Ferrara et al.   Pediatric Rheumatology

Associations between gene polymorphisms and treatment outcomes of methotrexate in patients with juvenile idiopathic arthritis

(2018) Yuehong Chen et al.   PHARMACOGENOMICS

In the Pursuit of Methotrexate Treatment Response Biomarker in Juvenile Idiopathic Arthritis—Are We Getting Closer to Personalised Medicine?

(2017) Justyna Roszkiewicz et al.   Current Rheumatology Reports

A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier

(2016) Do-Geun Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanism of action of methotrexate in rheumatoid arthritis and the search for biomarkers

(2016) Philip M. Brown et al.   Nature Reviews Rheumatology

Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases

(2016) Bruce N. Cronstein et al.   Nature Reviews Rheumatology

Influence ofADORA2Agene polymorphism on leukoencephalopathy risk in MTX-treated pediatric patients affected by hematological malignancies

(2016) Shin-ichi Tsujimoto et al.   PEDIATRIC BLOOD & CANCER

Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome

(2016) Aurea Lima et al.   PHARMACOGENOMICS

Association of the ATIC 347 C/G polymorphism with responsiveness to and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis

(2016) Young Ho Lee et al.   RHEUMATOLOGY INTERNATIONAL

Mechanosensory Signaling in Enterochromaffin Cells and 5-HT Release: Potential Implications for Gut Inflammation

(2016) Andromeda Linan-Rico et al.   Frontiers in Neuroscience

Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action

(2012) Lisa K Stamp et al.   ARTHRITIS RESEARCH & THERAPY

High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: Development and validation of a methotrexate intolerance severity score

(2011) Maja Bulatović et al.   ARTHRITIS AND RHEUMATISM

A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release

(2011) Katia Varani et al.   ARTHRITIS RESEARCH & THERAPY

Rotavirus Stimulates Release of Serotonin (5-HT) from Human Enterochromaffin Cells and Activates Brain Structures Involved in Nausea and Vomiting

(2011) Marie Hagbom et al.   PLoS Pathogens

Much Ado about Adenosine: Adenosine Synthesis and Function in Regulatory T Cell Biology

(2010) P. B. Ernst et al.   JOURNAL OF IMMUNOLOGY

Methotrexate—how does it really work?

(2010) Edwin S. L. Chan et al.   Nature Reviews Rheumatology

Development and validation of a composite disease activity score for juvenile idiopathic arthritis

(2009) Alessandro Consolaro et al.   ARTHRITIS AND RHEUMATISM

The anti-inflammatory target A3 adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease

(2009) A. Ochaion et al.   CELLULAR IMMUNOLOGY

Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX

(2008) S. L. Hider et al.   RHEUMATOLOGY