Development of a High-Efficacy Reprogramming Method for Generating Human Induced Pluripotent Stem (iPS) Cells from Pathologic and Senescent Somatic Cells

Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts

(2019) Massoud Vosough et al.   PLoS One

Metabolomic and Transcriptional Analyses Reveal Atmospheric Oxygen During Human Induced Pluripotent Stem Cell Generation Impairs Metabolic Reprogramming

(2019) James Spyrou et al.   STEM CELLS

Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux

(2019) Jarmon G. Lees et al.   Stem Cells International

Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis

(2019) Yuuri Yasuoka et al.   MOLECULAR BIOLOGY AND EVOLUTION

GLIS1–3 transcription factors: critical roles in the regulation of multiple physiological processes and diseases

(2018) Anton M. Jetten   CELLULAR AND MOLECULAR LIFE SCIENCES

Biomarkers for the identification of cardiac fibroblast and myofibroblast cells

(2018) Emiri Tarbit et al.   HEART FAILURE REVIEWS

Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells

(2018) Alexandra J. Harvey et al.   PLoS One

Mechanism of human somatic reprogramming to iPS cell

(2017) Rika Teshigawara et al.   LABORATORY INVESTIGATION

Enhanced generation of iPSCs from older adult human cells by a synthetic five-factor self-replicative RNA

(2017) Naohisa Yoshioka et al.   PLoS One

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

(2017) Carmel M. O'Brien et al.   STEM CELLS

Biological Significance of the Suppression of Oxidative Phosphorylation in Induced Pluripotent Stem Cells

(2017) Cheng Zhang et al.   Cell Reports

Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts

(2016) Yo Seph Park et al.   BIOLOGICAL CHEMISTRY

Myofibroblasts

(2016) Boris Hinz   EXPERIMENTAL EYE RESEARCH

Nanog, Oct4 and Tet1 interplay in establishing pluripotency

(2016) Victor Olariu et al.   Scientific Reports

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

(2015) Davide Cacchiarelli et al.   CELL

Current advances in the generation of human iPS cells: implications in cell-based regenerative medicine

(2015) Ana Revilla et al.   Journal of Tissue Engineering and Regenerative Medicine

Inhibition of Transforming Growth Factor β (TGF-β) Signaling can Substitute for Oct4 Protein in Reprogramming and Maintain Pluripotency

(2014) Fangzhi Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A comparison of non-integrating reprogramming methods

(2014) Thorsten M Schlaeger et al.   NATURE BIOTECHNOLOGY

Generation of Human Induced Pluripotent Stem (iPS) Cells in Serum- and Feeder-Free Defined Culture and TGF-β1 Regulation of Pluripotency

(2014) Sachiko Yamasaki et al.   PLoS One

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA

(2013) Naohisa Yoshioka et al.   Cell Stem Cell

Technological Overview of iPS Induction from Human Adult Somatic Cells

(2013) Emilie Bayart et al.   CURRENT GENE THERAPY

Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts

(2013) K. Tanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Sendai Virus Vectors and their Potential Applications in Gene Therapy and Regenerative Medicine

(2012) Mahito Nakanishi et al.   CURRENT GENE THERAPY

Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

(2011) L. Lapasset et al.   GENES & DEVELOPMENT

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

(2011) H. Ban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

A chemical platform for improved induction of human iPSCs

(2009) Tongxiang Lin et al.   NATURE METHODS

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

The coming acceleration of global population ageing

(2008) Wolfgang Lutz et al.   NATURE