Distinct TP53 Mutation Types Exhibit Increased Sensitivity to Ferroptosis Independently of Changes in Iron Regulatory Protein Activity

Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism

(2019) Stephen L. Clarke et al.   Nutrients

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells

(2018) Amy Tarangelo et al.   Cell Reports

The Role of Ferroptosis in Cancer Development and Treatment Response

(2018) Bin Lu et al.   Frontiers in Pharmacology

Iron and Cancer

(2018) Suzy V. Torti et al.   Annual Review of Nutrition

A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation

(2017) Nathan B. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate

(2017) Pranavi Koppula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

(2017) Samantha W. Alvarez et al.   NATURE

Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation

(2017) David S. Liu et al.   Nature Communications

Transferrin receptor 1 upregulation in primary tumor and downregulation in benign kidney is associated with progression and mortality in renal cell carcinoma patients

(2017) Christopher J. Greene et al.   Oncotarget

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

(2017) Yangchun Xie et al.   Cell Reports

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An African-specific polymorphism in theTP53gene impairs p53 tumor suppressor function in a mouse model

(2016) Matthew Jennis et al.   GENES & DEVELOPMENT

Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression

(2016) Fumiyasu Okazaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase

(2016) Hong Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression

(2016) Shang-Jui Wang et al.   Cell Reports

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis

(2016) Yue-Qi Wang et al.   Frontiers in Aging Neuroscience

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Targeting cancer by binding iron: Dissecting cellular signaling pathways

(2015) Goldie Y.L. Lui et al.   Oncotarget

Regulation of iron homeostasis by the p53-ISCU pathway

(2015) Yuki Funauchi et al.   Scientific Reports

Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function

(2014) Jia Shen et al.   Cell Reports

IRP2 Regulates Breast Tumor Growth

(2013) Wei Wang et al.   CANCER RESEARCH

Novel Chelators for Cancer Treatment: Where Are We Now?

(2012) Angelica M. Merlot et al.   ANTIOXIDANTS & REDOX SIGNALING

Mammalian iron metabolism and its control by iron regulatory proteins

(2012) Cole P. Anderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Dimebon activates autophagosome components in human neuroblastoma SH-SY5Y cells

(2012) I. V. Khritankova et al.   Doklady Biochemistry and Biophysics

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Heme Oxygenase-1 Protects Human Melanocytes from H2O2-Induced Oxidative Stress via the Nrf2-ARE Pathway

(2011) Zhe Jian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hypoxia Inducible Factor-2α Is Translationally Repressed in Response to Dietary Iron Deficiency in Sprague-Dawley Rats

(2011) McKale R. Davis et al.   JOURNAL OF NUTRITION

The Importance of the Stem Cell Marker Prominin-1/CD133 in the Uptake of Transferrin and in Iron Metabolism in Human Colon Cancer Caco-2 Cells

(2011) Erika Bourseau-Guilmain et al.   PLoS One

Mutant p53 R248Q but not R248W enhances in vitro invasiveness of human lung cancer NCI-H1299 cells

(2010) Kazuhito Yoshikawa et al.   BIOMEDICAL RESEARCH-TOKYO

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

(2010) Mark M. Pomerantz et al.   PLoS Genetics

Post-transcriptional Modulation of Iron Homeostasis during p53-dependent Growth Arrest

(2008) Fan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY