Placental Epigenome-Wide Association Study Identified Loci Associated with Childhood Adiposity at 3 Years of Age

Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity

(2019) Shouneng Peng et al.   PLoS Genetics

Placental DNA Methylation Adaptation to Maternal Glycemic Response in Pregnancy

(2018) Andres Cardenas et al.   DIABETES

FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes

(2018) Xiaoyan Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Preconception Micronutrient Supplementation Reduced Circulating Branched Chain Amino Acids at 12 Weeks Gestation in an Open Trial of Guatemalan Women Who Are Overweight or Obese

(2018) Sarah Borengasser et al.   Nutrients

Placental lipoprotein lipase DNA methylation alterations are associated with gestational diabetes and body composition at 5 years of age

(2017) Valérie Gagné-Ouellet et al.   Epigenetics

DNA methylation in blood from neonatal screening cards and the association with BMI and insulin sensitivity in early childhood

(2017) S J van Dijk et al.   INTERNATIONAL JOURNAL OF OBESITY

Skap2 is required for β 2 integrin–mediated neutrophil recruitment and functions

(2017) Mark Boras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The correlation of methylation levels measured using Illumina 450K and EPIC BeadChips in blood samples

(2017) Mark W Logue et al.   Epigenomics

Cord blood DNA methylation and adiposity measures in early and mid-childhood

(2017) Jacob K. Kresovich et al.   Clinical Epigenetics

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

(2017) Karen Lillycrop et al.   EBioMedicine

Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation

(2017) Kohzoh Mitsuya et al.   PLoS One

DNA-Methylation and Body Composition in Preschool Children: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study

(2017) Peter Rzehak et al.   Scientific Reports

Hypomethylation within gene promoter regions and type 1 diabetes in discordant monozygotic twins

(2016) Emon Elboudwarej et al.   JOURNAL OF AUTOIMMUNITY

Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies

(2016) Elior Rahmani et al.   NATURE METHODS

3D Cohort Study: The Integrated Research Network in Perinatology of Quebec and Eastern Ontario

(2016) William D. Fraser et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

“Gap hunting” to characterize clustered probe signals in Illumina methylation array data

(2016) Shan V. Andrews et al.   Epigenetics & Chromatin

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

(2016) Sebastian Moran et al.   Epigenomics

Genetics of Glucose regulation in Gestation and Growth (Gen3G): a prospective prebirth cohort of mother–child pairs in Sherbrooke, Canada

(2016) Laetitia Guillemette et al.   BMJ Open

Childhood overweight and obesity trends in Canada

(2016) Deepa P. Rao et al.   Health Promotion and Chronic Disease Prevention in Canada-Research Policy and Practice

Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood

(2015) R C Huang et al.   Epigenetics

Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation

(2015) Christiana A. Demetriou et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children

(2015) Gemma C Sharp et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development

(2015) Stephan Niebler et al.   ARTHRITIS RESEARCH & THERAPY

HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT

(2015) Shuo Wang et al.   PLoS One

Epigenetic Mechanisms Affecting Regulation of Energy Balance: Many Questions, Few Answers

(2014) Robert A. Waterland   Annual Review of Nutrition

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Formin 1 and Filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate

(2014) J. Hu et al.   HUMAN MOLECULAR GENETICS

Nutrition in early life and the programming of adult disease: a review

(2014) S. C. Langley-Evans   JOURNAL OF HUMAN NUTRITION AND DIETETICS

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Incidence of Childhood Obesity in the United States

(2014) Solveig A. Cunningham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?

(2014) M. A. Hanson et al.   PHYSIOLOGICAL REVIEWS

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2014) Cecilia M. Lindgren et al.   PLoS Genetics

Correlations among adiposity measures in school-aged children

(2013) Caroline E Boeke et al.   BMC Pediatrics

Degree of methylation ofZAC1(PLAGL1) is associated with prenatal and post-natal growth in healthy infants of the EDEN mother child cohort

(2013) Salah Azzi et al.   Epigenetics

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

A Prospective Study of LINE-1DNA Methylation and Development of Adiposity in School-Age Children

(2013) Wei Perng et al.   PLoS One

Epigenetic Influences That Modulate Infant Growth, Development, and Disease

(2012) Naveed Hussain   ANTIOXIDANTS & REDOX SIGNALING

Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values

(2012) B. S. Pedersen et al.   BIOINFORMATICS

Revisiting the housekeeping genes of human placental development and insufficiency syndromes

(2012) S. Drewlo et al.   PLACENTA

DNA Methylation Patterns in Cord Blood DNA and Body Size in Childhood

(2012) Caroline L. Relton et al.   PLoS One

An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity

(2012) Peter Kuehnen et al.   PLoS Genetics

Programming towards Childhood Obesity

(2011) Patrick Tounian   ANNALS OF NUTRITION AND METABOLISM

Initial- and Processive-Cut Products Reveal Cellobiohydrolase Rate Limitations and the Role of Companion Enzymes

(2011) Jerome M. Fox et al.   BIOCHEMISTRY

Postnatal Growth and DNA Methylation Are Associated With Differential Gene Expression of the TACSTD2 Gene and Childhood Fat Mass

(2011) A. Groom et al.   DIABETES

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

The global obesity pandemic: shaped by global drivers and local environments

(2011) Boyd A Swinburn et al.   LANCET

Nutrition, Epigenetics, and Developmental Plasticity: Implications for Understanding Human Disease

(2010) Graham C. Burdge et al.   Annual Review of Nutrition

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory network

(2010) N. de Croze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cartilage-specific transcription factor Sox9 regulates AP-2ε expression in chondrocytes

(2009) Ann-Kathrin Wenke et al.   FEBS Journal

Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development

(2009) Ann-Kathrin Wenke et al.   FEBS Journal

BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

(2009) H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetics at the Epicenter of Modern Medicine

(2008) Andrew P. Feinberg   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

GAPDH, 18S rRNA and YWHAZ are Suitable Endogenous Reference Genes for Relative Gene Expression Studies in Placental Tissues from Human Idiopathic Fetal Growth Restriction

(2008) P. Murthi et al.   PLACENTA