Article
Immunology
Magdalena Szmulik, Zuzanna Trzesniewska-Ofiara, Mariola Mendrycka, Agnieszka Wozniak-Kosek
Summary: Automated urine technology provides standard urinalysis data to support clinicians in screening and managing urinary tract infections. This study investigated two automated urinalysis systems and analyzed the chemical components and sediment results to determine their potential as indicators for UTIs. The results showed that the counts of bacteria and leukocytes in urine can be useful indicators for urinary tract infections. Accurate urinalysis can serve as a future tool to connect clinical and microbiology laboratories.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Angela Maione, Emilia Galdiero, Luigi Cirillo, Edvige Gambino, Maria Assunta Gallo, Francesca Paola Sasso, Arianna Petrillo, Marco Guida, Marilena Galdiero
Summary: Community-acquired urinary tract infections are the most common infectious diseases in the community setting. This study aimed to determine the incidence and resistance profiles of causative agents of UTIs. The majority of positive cases were found in elderly individuals, with Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis being the most isolated pathogens. The low resistance rates against certain antibiotics suggest them as potential appropriate therapies for CA-UTIs.
Article
Multidisciplinary Sciences
Lorette Victorine Yimgang, Rufin Marie Kouipou Toghueo, Ines Michele Kanko Mbekou, Darline Dize, Fabrice Fekam Boyom
Summary: This study explores the potential of crude metabolites from endophytic fungi isolated from Annona muricata as sources of antibiotic drugs to combat uropathogens and reduce oxidative stress. The active extracts from these fungi showed antibacterial activity, antioxidant properties, and cytotoxicity against Vero cell lines, emphasizing their potential as novel drug discoveries in treating urinary tract infections.
Article
Medicine, General & Internal
Xuhui Li, Hua Fan, Hao Zi, Hankun Hu, Binghui Li, Jiao Huang, Pengcheng Luo, Xiantao Zeng
Summary: This study aimed to estimate the global and regional burden of bacterial antimicrobial resistance (AMR) in urinary tract infections (UTI) in 2019. The results showed that globally, there were approximately 64.89 thousand deaths attributed to and 0.26 million deaths associated with bacterial AMR in UTI. Escherichia coli and Klebsiella pneumoniae had the highest resistance rates, including resistance to fluoroquinolones, carbapenems, and third-generation cephalosporins. Tailored strategies, such as enhanced surveillance and rational use of antibiotics, should be developed for different regions based on their specific pathogen-antibiotic situations and resources.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Huan-Cheng Lai, Shih-Ni Chang, Hsiao-Chuan Lin, Yu-Lung Hsu, Hsiu-Mei Wei, Chin-Chi Kuo, Kao-Pin Hwang, Hsiu-Yin Chiang
Summary: This study found an association between urine pH and specific uropathogens in pediatric patients, with the prevalence of P. mirabilis increasing significantly across higher pH categories. Age and urine pH are both associated with certain causative uropathogens in UTIs. Future studies should further investigate the role of urine pH in predicting uropathogens and UTI.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2021)
Article
Infectious Diseases
Muhammad Ajmal Khan, Atta Ur Rahman, Bakhtawar Khan, Samiah Hamad Al-Mijalli, Amal S. Alswat, Aftab Amin, Refaat A. Eid, Mohamed Samir A. Zaki, Sadia Butt, Jamshaid Ahmad, Eman Fayad, Amin Ullah
Summary: Urinary tract infections (UTIs) are common in the population of Khyber Pakhtunkhwa (KP), Pakistan, with Klebsiella pneumoniae being the most prevalent uropathogen. Imipenem was identified as the most effective antibiotic, while cefuroxime and ciprofloxacin showed the least effectiveness.
Review
Integrative & Complementary Medicine
Herman van Wietmarschen, Noortje van Steenbergen, Esther van der Werf, Erik Baars
Summary: Antimicrobial resistance is a global issue, and traditional herbal medicine has been found to be effective in controlling symptoms of urinary tract infections and reducing antibiotic use. Cranberry and traditional Chinese herbal formulas have been shown to be beneficial for UTIs, and Rosa canina may help prevent UTIs in women undergoing caesarean section.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Article
Infectious Diseases
Camilla Smoglica, Giulia Evangelisti, Caterina Fani, Fulvio Marsilio, Michele Trotta, Francesca Messina, Cristina Esmeralda Di Francesco
Summary: The available data on antimicrobial resistance in pets are limited compared to those collected for food-producing animals. In this study, laboratory investigations were conducted on dogs and cats with urinary tract infections in Central Italy to provide additional data on bacterial urinary pathogens and their antimicrobial resistance patterns. The study found a high prevalence of resistant bacteria and a significant proportion of isolates classified as multidrug-resistant.
Article
Veterinary Sciences
Fergus Allerton, Koen B. Pouwels, Julien Bazelle, Sarah Caddy, Andria Cauvin, Luisa De Risio, James Swann, James Warland, Andrew Kent
Summary: Current research on course lengths for common canine infections is limited. This prospective study aims to determine the shortest course duration for female dogs with lower urinary tract signs, providing guidelines for antimicrobial decision-making in clinical practice.
BMC VETERINARY RESEARCH
(2021)
Article
Infectious Diseases
Leesa Lin, Stephan Harbarth, James R. Hargreaves, Xudong Zhou, Leah Li
Summary: Inappropriate use of antibiotics for upper respiratory tract infections (URTIs) in Chinese children is common. Parents who perceive antibiotics as effective for treating the common cold and fever, have access to non-prescription antibiotics, and perceive the infection as more severe are more likely to use antibiotics. Multifaceted interventions are needed to address the issue of self-medication, over-prescription, and inappropriate demands for antibiotics.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2021)
Article
Infectious Diseases
Guadalupe Miranda-Novales, Karen Flores-Moreno, Yolanda Lopez-Vidal, Samuel Ponce de Leon-Rosales
Summary: This study evaluated the antimicrobial susceptibility patterns of Escherichia coli and Klebsiella pneumoniae, and found that multidrug-resistant bacteria represented 61% of all isolates.
Article
Engineering, Environmental
Jian Lu, Yuxuan Zhang, Jun Wu, Jianhua Wang
Summary: This study investigated the impact of antimicrobial peptide intervention on antimicrobial resistance in aquaculture by analyzing the abundance of antibiotic resistance genes (ARGs) in various samples. The results showed that cecropin treatment significantly reduced the absolute abundance of ARGs, while antibiotic treatment had the opposite effect. Network analysis revealed that cecropin treatment could decrease the occurrence of multi-drug resistant bacteria and the correlation between genera and ARGs.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Ileana Adela Vacaroiu, Elena Cuiban, Bogdan Florin Geavlete, Valeriu Gheorghita, Cristiana David, Cosmin Victor Ene, Catalin Bulai, Gabriela Elena Lupusoru, Mircea Lupusoru, Andra Elena Balcangiu-Stroescu, Larisa Florina Feier, Ioana Sorina Simion, Daniela Radulescu
Summary: CKD is a significant risk factor for antimicrobial resistance and multi-drug resistance.
Review
Biochemistry & Molecular Biology
Maria Maisto, Fortuna Iannuzzo, Ettore Novellino, Elisabetta Schiano, Vincenzo Piccolo, Gian Carlo Tenore
Summary: Urinary tract infections (UTIs) are a common bacterial infection, especially in women. The main etiological agents are E. coli, Pseudomonas aeruginosa, and Proteus mirabilis. Due to the increase in antimicrobial resistance, there is a need for natural alternatives for UTI treatment. This review summarizes the potential therapeutic effects of natural polyphenol-based nutraceuticals and foods through in vitro and in vivo studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Microbiology
Kayoko Hayakawa, Yasufumi Matsumura, Kohei Uemura, Shinya Tsuzuki, Aki Sakurai, Ryutaro Tanizaki, Koh Shinohara, Takehiro Hashimoto, Ryota Hase, Takashi Matono, Hideaki Kato, Momoko Mawatari, Hiroshi Hara, Yukihiro Hamada, Sho Saito, Norio Ohmagari, Yohei Doi
Summary: Cefmetazole showed clinical and bacteriological effectiveness comparable to meropenem against invasive urinary tract infection due to ESBLECs.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2023)
Article
Nursing
Wendy Swallow, Jill C. Roberts
JOURNAL OF SCHOOL NURSING
(2016)
Article
Microbiology
William Veguilla, K. Kealy Peak, Vicki A. Luna, Jill C. Roberts, Carisa R. Davis, Andrew C. Cannons, Philip Amuso, Jacqueline Cattani
JOURNAL OF CLINICAL MICROBIOLOGY
(2008)
Article
Biotechnology & Applied Microbiology
Aparna Tatavarthy, Kealy Peak, William Veguilla, Teresa Cutting, Valerie J. Harwood, Jill Roberts, Philip Amuso, Jacqueline Cattani, Andrew Cannons
JOURNAL OF FOOD PROTECTION
(2009)
Article
Biotechnology & Applied Microbiology
Jill C. Roberts
BIOMED RESEARCH INTERNATIONAL
(2014)
Article
Medicine, General & Internal
Jeffery L. Sumter, Jill Roberts, Adrienne Goodrich-Doctor, Thomas J. Mason
Article
Environmental Sciences
Jeremy A. Corrigan, Steven R. Butkus, Michael E. Ferris, Jill C. Roberts
Summary: The study investigated Clam Beach and its surrounding watershed in Northern California, using traditional FIB and MST methods to identify sources of contamination. It found that the beach was mainly impacted by birds, while the watershed was influenced by ruminants. Human impact was minimal, posing low health risks.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Denise Lopez, Jill Roberts, Marie Bourgeois, Joshua Kootstra, Sharon Minnick, Allison Black, Joshua Mauss, Nick Flores
Summary: The C29197T mutation causes N-gene target failure in SARS-CoV-2 testing. We identified a high local prevalence, partially due to a disproportionately large infection cluster of unknown origin. This study emphasizes the importance of sequencing at a local jurisdictional level and highlights the risk of point mutations in clinical test performance.
Article
Microbiology
Ronan K. Carroll, Whittney N. Burda, Jill C. Roberts, Kealy K. Peak, Andrew C. Cannons, Lindsey N. Shaw
GENOME ANNOUNCEMENTS
(2013)
Article
Biochemical Research Methods
Jill C. Roberts, Andrew C. Cannons, Philip T. Amuso, Jacqueline Cattani
JOURNAL OF MICROBIOLOGICAL METHODS
(2006)
Article
Microbiology
JC Roberts, KV Singh, PC Okhuysen, BE Murray
JOURNAL OF CLINICAL MICROBIOLOGY
(2004)