Article
Biotechnology & Applied Microbiology
K. Jena, S. Ananta, J. Akthar, A. Patnaik, S. Das, J. Singh, K. Sathyanarayana, P. K. Kar, B. K. Das, Md. Abul Hassan, Falguni Panda, B. Paital
Summary: This study characterized the chitin and chitosan obtained from tasar silkworm spent pupae and evaluated their physical characteristics and properties. The results showed that the obtained chitosan had similar properties to other chitosan samples and exhibited antioxidant and antimicrobial activity. Moreover, the application of chitosan coating extended the shelf-life of bananas.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Article
Food Science & Technology
Abdul Sadat, Trishanjan Biswas, Marlon H. Cardoso, Rittick Mondal, Ashmita Ghosh, Paulami Dam, Jannatun Nesa, Joydeep Chakraborty, Debjoy Bhattacharjya, Octavio L. Franco, Debnirmalya Gangopadhyay, Amit K. Mandal
Summary: Silkworm pupae (SWP), a by-product of the silk reeling industry, have high nutritional and therapeutic value, making them a potential dietary supplement, pharmaceutical, and healthcare product. SWP contains a variety of nutrients and exhibits diverse biological properties, including antioxidant, antimicrobial, and anti-inflammatory effects.
CURRENT OPINION IN FOOD SCIENCE
(2022)
Review
Engineering, Marine
Manikandan Muthu, Suraj Shiv Charan Pushparaj, Judy Gopal, Iyyakkannu Sivanesan
Summary: Chitosan, a natural biodegradable polymer extracted from marine shell wastes, has been widely used in biomedical applications due to its exceptional qualities. This review focuses on the biomedical highlights of chitosan-based microspheres (MS), particularly its antimicrobial properties against bacteria, fungi, and viruses. The gaps in its usage for antimicrobial investigations are addressed and future recommendations and expansion opportunities are suggested.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Zhicun Sheng, Ainan Guo, Jing Wang, Xiaolan Chen
Summary: This study performed chitosan extraction from fly pupae using a traditional chemical method with modifications, and investigated its physicochemical properties and antimicrobial activity. The results showed that the improved method can produce valuable chitosan antimicrobial agent from this alternative natural source.
Article
Polymer Science
Majid Pakizeh, Ali Moradi, Toktam Ghassemi
Summary: Chitin-based materials are promising in biomedical applications. Waste shrimp shells can be chemically extracted to produce high-value chitosan products. Future research should focus on improving extraction and production techniques for chitin.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Behiye Taser, Hakan Ozkan, Ahmet Adiguzel, Tugba Orak, Mustafa Ozkan Baltaci, Mesut Taskin
Summary: This study investigated the extraction of chitin from shrimp shell powder using P.jamilae, the preparation of chitosan with high deacetylation degree, and the antimicrobial and antioxidant activity of the prepared chitosan. The results showed that P.jamilae has high protease activity and protein removal potential, leading to successful deproteinization and chitin extraction. The prepared chitosan displayed higher DPPH scavenging activity and antimicrobial activity compared to commercial chitosan.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Maria Cermeno, Carmen Bascon, Miryam Amigo-Benavent, Manuel Felix, Richard J. FitzGerald
Summary: Silkworm pupae hydrolysates exhibited significant antioxidant activity, with Alcalase and Prolyve hydrolysates having the highest scavenging activities, and Flavourzyme and Brewers Clarex hydrolysates showing enhanced ferric reducing antioxidant power. Peptides SWFVTPF and NDVLFF demonstrated the highest antioxidant activity in HepG2 cells.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Biochemistry & Molecular Biology
Isabel Rodriguez-Veiga, Niuris Acosta, Inmaculada Aranaz, Aldona Dobrzycka-Krahel
Summary: The demand for chitin and chitosan is increasing rapidly in various industries. This paper evaluates Saduria entomon as a source for chitin and chitosan isolation and finds that it has promising antimicrobial and antioxidant properties, making it a potential source for biomedical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Anton R. Egorov, Omar Khubiev, Vasili V. Rubanik, Vasili V. Rubanik Jr, Nikolai N. Lobanov, Serguei V. Savilov, Anatoly A. Kirichuk, Ilya S. Kritchenkov, Alexander G. Tskhovrebov, Andreii S. Kritchenkov
Summary: An ultrasonic approach has been developed for the synthesis of selenium-containing derivatives of chitin and chitosan. The synthetic procedure is simple, efficient, and environmentally friendly. The derivatives show high antibacterial and antifungal activity, surpassing the effect of classic antibiotics. Furthermore, they exhibit promising transfection activity and act as efficient catalysts for alcohol oxidation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Medicinal
Luciana C. Gomes, Sara Faria, Jesus Valcarcel, Jose A. Vazquez, Miguel A. Cerqueira, Lorenzo Pastrana, Ana Bourbon, Filipe J. Mergulhao
Summary: This study focused on developing poly(lactic acid) surfaces coated with beta-chitosan and beta-chitooligosaccharides from marine waste, which showed strong antimicrobial properties against Escherichia coli and Pseudomonas putida. Chitosan films with higher molecular weight demonstrated increased antibiofilm activity under simulated food storage conditions, contributing to the reuse of marine waste.
Review
Biochemistry & Molecular Biology
Pawel Poznanski, Amir Hameed, Waclaw Orczyk
Summary: Chitosan, derived from chitin, has strong antifungal activity and is biodegradable, biocompatible, and non-toxic. Chitosan nanoparticles can enhance its antifungal activity. Various parameters, such as molecular weight, degree of deacetylation, acetylation pattern, concentration, and protonation of chitosan, affect its antifungal activity and nanoparticle properties. Understanding these parameters is important for designing environmentally friendly plant protection strategies.
Article
Multidisciplinary Sciences
Gengxin Hao, Yanyu Hu, Linfan Shi, Jun Chen, Aixiu Cui, Wuyin Weng, Kazufumi Osako
Summary: Chitosan obtained from swimming crab shells via subcritical water pretreatment had lower yield and molecular weight compared to those prepared via sodium hydroxide pretreatment, but exhibited similar molecular structures and better thermal stability. Subcritical water pretreatment showed potential for crustacean shell pretreatment and chitosan preparation.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Mevin Kiprotich Lagat, Samuel Were, Francis Ndwigah, Violah Jepkogei Kemboi, Carolyne Kipkoech, Chrysantus Mbi Tanga
Summary: This study conducted a comparative analysis of chemical and biological extraction of chitin and chitosan from black soldier fly pupal exuviae for the first time, revealing the promising antimicrobial properties of chitosan derived from black soldier fly pupal exuviae against various strains of bacteria.
Article
Microbiology
Yanina S. Rizzi, Petra Happel, Sandra Lenz, Mounashree J. Urs, Martin Bonin, Stefan Cord-Landwehr, Ratna Singh, Bruno M. Moerschbacher, Regine Kahmann
Summary: The basidiomycete Ustilago maydis, a biotrophic fungus, possesses a family of chitin deacetylases (CDAs) with seven genes that play discrete and redundant roles in virulence and cell wall integrity. The study shows that different CDAs have specific functions in evading plant immune recognition and modifying chitin to chitosan. Surprisingly, the simultaneous inactivation of all seven genes is not tolerated, indicating the essential role of chitosan for the fungus's viability.
Article
Chemistry, Applied
Zhiwen Ding, Sibtain Ahmed, Jiahao Hang, Haoyu Mi, Xiaoyue Hou, Guang Yang, Zhifa Huang, Xiaoyue Lu, Wei Zhang, Shu Liu, Yaowei Fang
Summary: The study enhanced the deacetylation activity of chitin deacetylases from Arthrobacter through site-directed mutagenesis, leading to improved deacetylation efficiency on crystalline chitin. The mutant Mut-2-8 was found to have potential applications in the chitosan industry.
CARBOHYDRATE POLYMERS
(2021)
Article
Construction & Building Technology
Vijaykumar Guna, Manikandan Ilangovan, Muzamil Hassan Rather, B. Giridharan, B. Prajwal, K. Vamshi Krishna, Krishna Venkatesh, Narendra Reddy
JOURNAL OF BUILDING ENGINEERING
(2020)
Article
Chemistry, Applied
Manikandan Ilangovan, Vijaykumar Guna, B. Prajwal, Qiuran Jiang, Narendra Reddy
CARBOHYDRATE POLYMERS
(2020)
Article
Biotechnology & Applied Microbiology
Divya Nataraj, Vijaykumar Guna, Prajwal Battampara, Nagananda Govinahalli Shivashankara, Paola Rizzarelli, Narendra Reddy
Summary: Proteins extracted from Pongamia pinnata oil meal were converted into films and packaging products with excellent antioxidant properties and antimicrobial activity.
JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
(2021)
Article
Environmental Sciences
Prajwal Battampara, Deepak Ingale, Vijaykumar Guna, Uma Ullas Pradhan, Narendra Reddy
Summary: The study demonstrated that discarded wool and fish scales can be used as electrolytes in a biochemical fuel cell, generating up to 418 mV of energy. By adjusting parameters and using specific materials, the performance and output of the cells can be maximized. Due to ease of preparation and reusability, this technology has the potential to be a feasible solution for generating small amounts of energy.
WASTE AND BIOMASS VALORIZATION
(2021)
Article
Materials Science, Textiles
Chunyan Hu, Prajwal Battampara, Vijaykumar Guna, Narendra Reddy
Summary: Cellulose fibers with high cellulose and lignin content were extracted from Areca nut shells and subjected to alkali treatment, resulting in increased tensile strength and elongation. Morphological changes and improved thermal stability make these fibers suitable for composite and other applications, potentially adding substantial value and promoting sustainable use of the shells.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Materials Science, Multidisciplinary
Aayush Rai, Seemesh Bhaskar, Prajwal Battampara, Narendra Reddy, Sai Sathish Ramamurthy
Summary: Silver nanoparticles with anisotropic geometries were synthesized using proteins extracted from sesame oil seed cakes and UV-exposure methodology, showing potential applications in different functional nanointerfaces. The obtained AgNPs were evaluated in surface plasmon-coupled emission (SPCE) platform, demonstrating enhanced emission for femtomolar sensing of SPCE reporter molecule rhodamine B (RhB) using cellphones.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)