ROR agonist hampers the proliferation and survival of postactivated CD8 + T cells through the downregulation of cholesterol synthesis‐related genes
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
ROR agonist hampers the proliferation and survival of postactivated CD8
+
T cells through the downregulation of cholesterol synthesis‐related genes
Authors
Keywords
-
Journal
IMMUNOLOGY AND CELL BIOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-09-18
DOI
10.1111/imcb.12406
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation
- (2018) Yao Chen et al. Frontiers in Immunology
- Cholesterol Metabolism in T Cells
- (2017) Andreas Bietz et al. Frontiers in Immunology
- SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression
- (2015) Laurent Vergnes et al. JOURNAL OF LIPID RESEARCH
- Discrete functions of nuclear receptor Rev-erb couple metabolism to the clock
- (2015) Y. Zhang et al. SCIENCE
- The Therapeutic Potential of Nuclear Receptor Modulators for Treatment of Metabolic Disorders: PPARγ, RORs, and Rev-erbs
- (2014) David P. Marciano et al. Cell Metabolism
- REV-ERB and ROR nuclear receptors as drug targets
- (2014) Douglas J. Kojetin et al. NATURE REVIEWS DRUG DISCOVERY
- Metabolic Regulation of T Lymphocytes
- (2013) Nancie J. MacIver et al. Annual Review of Immunology
- Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
- (2013) Yoko Kidani et al. NATURE IMMUNOLOGY
- Multiple Regulatory Layers of SREBP1/2 by SIRT6
- (2013) Sivan Elhanati et al. Cell Reports
- Pharmacologic Repression of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γ Is Therapeutic in the Collagen-Induced Arthritis Experimental Model
- (2013) Mi Ra Chang et al. Arthritis & Rheumatology
- Type-I IFN drives the differentiation of short-lived effector CD8+T cells in vivo
- (2011) Melanie Wiesel et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Identification of SR1078, a Synthetic Agonist for the Orphan Nuclear Receptors RORα and RORγ
- (2010) Yongjun Wang et al. ACS Chemical Biology
- A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)
- (2010) Yongjun Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Metabolism in T cell activation and differentiation
- (2010) Erika L Pearce CURRENT OPINION IN IMMUNOLOGY
- T Cell Receptor-Dependent Regulation of Lipid Rafts Controls Naive CD8+ T Cell Homeostasis
- (2010) Jae-Ho Cho et al. IMMUNITY
- The metabolic life and times of a T-cell
- (2010) Ryan D. Michalek et al. IMMUNOLOGICAL REVIEWS
- Characterization of the Human Insulin-induced Gene 2 (INSIG2) Promoter
- (2010) Ana Fernández-Alvarez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity
- (2009) Jihong Xu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response
- (2008) Steven J. Bensinger et al. CELL
- T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
- (2008) Xuexian O. Yang et al. IMMUNITY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started