Review: Pathogenesis of Helicobacter pylori infection

CagA–ASPP2 complex mediates loss of cell polarity and favors H. pylori colonization of human gastric organoids

(2020) Ludovico Buti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils

(2020) Ina-Kristin Behrens et al.   mBio

Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

(2020) Jennifer A Taylor et al.   eLife

Helicobacter pylori Dampens HLA-II Expression on Macrophages via the Up-Regulation of miRNAs Targeting CIITA

(2020) Gaia Codolo et al.   Frontiers in Immunology

DNA Hypermethylation Downregulates Telomerase Reverse Transcriptase (TERT) during H. pylori-Induced Chronic Inflammation

(2020) Françoise I. Bussière et al.   Journal of Oncology

Identification of Pathogenicity Island Genes Associated with Loss of Type IV Secretion Function during Murine Infection with Helicobacter pylori

(2020) Lori M. Hansen et al.   INFECTION AND IMMUNITY

Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells

(2020) Manikandan Palrasu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution

(2019) Kaiming Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori

(2019) Lennart Pfannkuch et al.   FASEB JOURNAL

Non-helical Helicobacter pylori show altered gland colonization and elicit less gastric pathology during chronic infection

(2019) Laura E. Martínez et al.   INFECTION AND IMMUNITY

A genome-wide Helicobacter pylori morphology screen uncovers a membrane spanning helical cell shape complex

(2019) Desirée C. Yang et al.   JOURNAL OF BACTERIOLOGY

Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization

(2019) Min Su et al.   JOURNAL OF MOLECULAR BIOLOGY

Modification of the Gastric Mucosal Microbiota by a Strain-Specific Helicobacter pylori Oncoprotein and Carcinogenic Histologic Phenotype

(2019) Jennifer M. Noto et al.   mBio

High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach

(2019) Connie Fung et al.   PLOS BIOLOGY

VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1

(2019) Mariana I. Capurro et al.   Nature Microbiology

Agent-Based Modeling Demonstrates How Local Chemotactic Behavior Can Shape Biofilm Architecture

(2019) Emily G. Sweeney et al.   mSphere

Helicobacter pylori infection promotes epithelial-to-mesenchymal transition of gastric cells by upregulating LAPTM4B

(2019) Shengfei Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Helicobacter pylori use TlpB receptor to sense sites of gastric injury

(2019) Hikaru Hanyu et al.   INFECTION AND IMMUNITY

The Cyclopropane Fatty Acid Synthase Mediates Antibiotic Resistance and Gastric Colonization of Helicobacter pylori

(2019) Xueqing Jiang et al.   JOURNAL OF BACTERIOLOGY

Helicobacter pylori CagA promotes the malignant transformation of gastric mucosal epithelial cells through the dysregulation of the miR‐155/KLF4 signaling pathway

(2019) Yang Ou et al.   MOLECULAR CARCINOGENESIS

Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

(2019) Florent Ailloud et al.   Nature Communications

Excision and transfer of an integrating and conjugative element in a bacterial species with high recombination efficiency

(2019) Evelyn Weiss et al.   Scientific Reports

Structure of the Helicobacter pylori Cag type IV secretion system

(2019) Jeong Min Chung et al.   eLife

Deregulation of miRNA in Helicobacter pylori-Induced Gastric MALT Lymphoma: From Mice to Human

(2019) Alice Blosse et al.   Journal of Clinical Medicine

Targeted mobilization of Lrig1+ gastric epithelial stem cell populations by a carcinogenic Helicobacter pylori type IV secretion system

(2019) Lydia E. Wroblewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori senses bleach (HOCl) as a chemoattractant using a cytosolic chemoreceptor

(2019) Arden Perkins et al.   PLOS BIOLOGY

HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach

(2019) Elise Gasiorowski et al.   PLoS Pathogens

Upexpression of BHLHE40 in gastric epithelial cells increases CXCL12 production through interaction with p‐STAT3 inHelicobacter pylori‐associated gastritis

(2019) Yong‐Sheng Teng et al.   FASEB JOURNAL

Tetramerization at Low pH Licenses DNA Methylation Activity of M.HpyAXI in the Presence of Acid Stress

(2019) Naveen Narayanan et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of the periplasmic DNA receptor for natural transformation of Helicobacter pylori

(2019) Prashant P. Damke et al.   Nature Communications

East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide

(2019) Hong Li et al.   PLoS Genetics

Helicobacter pylori Stress-Response: Definition of the HrcA Regulon

(2019) Davide Roncarati et al.   Microorganisms

Epigenetic silencing of microRNA-204 by Helicobacter pylori augments the NF-κB signaling pathway in gastric cancer development and progression

(2019) Peizhan Chen et al.   CARCINOGENESIS

T4SS-dependent TLR5 activation by Helicobacter pylori infection

(2019) Suneesh Kumar Pachathundikandi et al.   Nature Communications

Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori

(2019) Satoshi Yamashita et al.   Clinical Epigenetics

Cell injury triggers actin polymerization to initiate epithelial restitution

(2018) Eitaro Aihara et al.   JOURNAL OF CELL SCIENCE