Genome mining for natural product biosynthetic gene clusters in the Subsection V cyanobacteria

Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria

(2014) Alexandra Calteau et al.   BMC GENOMICS

Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria

(2014) Melinda L Micallef et al.   BMC MICROBIOLOGY

Identification and Characterization of a Welwitindolinone Alkaloid Biosynthetic Gene Cluster in the Stigonematalean CyanobacteriumHapalosiphon welwitschii

(2014) Matthew L. Hillwig et al.   CHEMBIOCHEM

Production of Squalene in Synechocystis sp. PCC 6803

(2014) Elias Englund et al.   PLoS One

Characterization of Cyanobacterial Hydrocarbon Composition and Distribution of Biosynthetic Pathways

(2014) R. Cameron Coates et al.   PLoS One

First report of microcystin-producing Fischerella sp. (Stigonematales, Cyanobacteria) in tropical Australia

(2014) Samuel Cirés et al.   TOXICON

High-Titer Heterologous Production in E. coli of Lyngbyatoxin, a Protein Kinase C Activator from an Uncultured Marine Cyanobacterium

(2013) Sarah E. Ongley et al.   ACS Chemical Biology

Biosynthesis of Ambiguine Indole Alkaloids in Cyanobacterium Fischerella ambigua

(2013) Matthew L. Hillwig et al.   ACS Chemical Biology

Aestuaramides, a Natural Library of Cyanobactin Cyclic Peptides Resulting from Isoprene-Derived Claisen Rearrangements

(2013) John A. McIntosh et al.   ACS Chemical Biology

Genome Mining Expands the Chemical Diversity of the Cyanobactin Family to Include Highly Modified Linear Peptides

(2013) Niina Leikoski et al.   CHEMISTRY & BIOLOGY

UV radiation-induced biosynthesis, stability and antioxidant activity of mycosporine-like amino acids (MAAs) in a unicellular cyanobacterium Gloeocapsa sp. CU2556

(2013) Rajesh P. Rastogi et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

(2013) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing

(2013) P. M. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules

(2013) R. D. Kersten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers

(2012) Stefan H. Knauer et al.   FEBS Journal

Genomes of Stigonematalean Cyanobacteria (Subsection V) and the Evolution of Oxygenic Photosynthesis from Prokaryotes to Plastids

(2012) Tal Dagan et al.   Genome Biology and Evolution

Stigonemapeptin, an Ahp-Containing Depsipeptide with Elastase Inhibitory Activity from the Bloom-Forming Freshwater Cyanobacterium Stigonema sp.

(2012) Hahk-Soo Kang et al.   JOURNAL OF NATURAL PRODUCTS

Evolution of Saxitoxin Synthesis in Cyanobacteria and Dinoflagellates

(2012) Jeremiah D. Hackett et al.   MOLECULAR BIOLOGY AND EVOLUTION

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

(2012) Jesko Koehnke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Heterologous Production of 4-O-Demethylbarbamide, a Marine Cyanobacterial Natural Product

(2012) Eun Ji Kim et al.   ORGANIC LETTERS

The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity

(2012) Nadine Ziemert et al.   PLoS One

Analysis of an Inactive Cyanobactin Biosynthetic Gene Cluster Leads to Discovery of New Natural Products from Strains of the Genus Microcystis

(2012) Niina Leikoski et al.   PLoS One

Nitrile-containing fischerindoles from the cultured cyanobacterium Fischerella sp.

(2012) Hyunjung Kim et al.   TETRAHEDRON

Nostophycin Biosynthesis Is Directed by a Hybrid Polyketide Synthase-Nonribosomal Peptide Synthetase in the Toxic Cyanobacterium Nostoc sp. Strain 152

(2011) David P. Fewer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Natural product biosyntheses in cyanobacteria: A treasure trove of unique enzymes

(2011) Jan-Christoph Kehr et al.   Beilstein Journal of Organic Chemistry

An ATP-Grasp Ligase Involved in the Last Biosynthetic Step of the Iminomycosporine Shinorine in Nostoc punctiforme ATCC 29133

(2011) Q. Gao et al.   JOURNAL OF BACTERIOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

Hapalocyclamide: a novel phytotoxic hexapeptide of the cyanobacterium Hapalosiphon sp.

(2011) Intira Koodkaew et al.   TETRAHEDRON LETTERS

Cyanobactins—ribosomal cyclic peptides produced by cyanobacteria

(2010) Kaarina Sivonen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family

(2010) Daniel H Haft et al.   BMC BIOLOGY

Natural Products Version 2.0: Connecting Genes to Molecules

(2010) Christopher T. Walsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural glycoconjugates with antitumor activity

(2010) Barbara La Ferla et al.   NATURAL PRODUCT REPORTS

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

The Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria

(2010) E. P. Balskus et al.   SCIENCE

Microbial Biosynthesis of Alkanes

(2010) A. Schirmer et al.   SCIENCE

Discovery of Unique Lanthionine Synthetases Reveals New Mechanistic and Evolutionary Insights

(2010) Yuki Goto et al.   PLOS BIOLOGY

Substrate Specificity and Scope of MvdD, a GRASP-like Ligase from the Microviridin Biosynthetic Gene Cluster

(2009) Benjamin Philmus et al.   ACS Chemical Biology

Organization, Evolution, and Expression Analysis of the Biosynthetic Gene Cluster for Scytonemin, a Cyanobacterial UV-Absorbing Pigment

(2009) C. M. Sorrels et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Gene Expression Patterns Associated with the Biosynthesis of the Sunscreen Scytonemin in Nostoc punctiforme ATCC 29133 in Response to UVA Radiation

(2009) T. Soule et al.   JOURNAL OF BACTERIOLOGY

An efficient DNA isolation protocol for filamentous cyanobacteria of the genus Arthrospira

(2009) Nicolas Morin et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Follow the leader: the use of leader peptides to guide natural product biosynthesis

(2009) Trent J Oman et al.   Nature Chemical Biology

Microcystin production by a freshwater spring cyanobacterium of the genus Fischerella

(2009) Marli Fátima Fiore et al.   TOXICON

Ribosomal Synthesis of Tricyclic Depsipeptides in Bloom-Forming Cyanobacteria

(2008) Nadine Ziemert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microcyclamide Biosynthesis in Two Strains of Microcystis aeruginosa: from Structure to Genes and Vice Versa

(2008) N. Ziemert et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Post-translational Modification in Microviridin Biosynthesis

(2008) Benjamin Philmus et al.   CHEMBIOCHEM

Isolation and Characterization of the Gene Associated with Geosmin Production in Cyanobacteria

(2008) Jiaoyang Jiang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Identification of Sesquiterpene Synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. Strain PCC 7120

(2008) S. A. Agger et al.   JOURNAL OF BACTERIOLOGY

A global assembly line for cyanobactins

(2008) Mohamed S Donia et al.   Nature Chemical Biology