NOX4‐dependent regulation of ENaC in hypertension and diabetic kidney disease

NOX inhibition: Pre-clinical and clinical studies in diabetic complications

(2020) Sofia Urner et al.   ANTIOXIDANTS & REDOX SIGNALING

Interplay between RNA-Binding Protein HuR and Nox4 As a Novel Therapeutic Target in Diabetic Kidney Disease

(2020) Qian Shi et al.   Molecular Metabolism

The WNK signaling pathway and salt-sensitive hypertension

(2020) Taisuke Furusho et al.   HYPERTENSION RESEARCH

Targeting the progression of chronic kidney disease

(2020) Marta Ruiz-Ortega et al.   Nature Reviews Nephrology

NOX4/H 2 O 2 /mTORC1 Pathway in Salt-Induced Hypertension and Kidney Injury

(2020) Vikash Kumar et al.   HYPERTENSION

NADPH oxidases: Current aspects and tools

(2020) Katrin Schröder   Redox Biology

Increased ENaC activity during kidney preservation in Wisconsin solution

(2019) Sherif Khedr et al.   BMC Nephrology

Hypertension as a Metabolic Disorder and the Novel Role of the Gut

(2019) Masami Tanaka et al.   CURRENT HYPERTENSION REPORTS

Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome

(2019) Justine M. Abais-Battad et al.   HYPERTENSION

Nox4 genetic inhibition in experimental hypertension and metabolic syndrome

(2018) Ghina Bouabout et al.   Archives of Cardiovascular Diseases

Nox4 in Renal Diseases: An Update

(2018) Qin Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease

(2018) Daria V. Ilatovskaya et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Potential benefits and harms of NADPH oxidase type 4 in the kidneys and cardiovascular system

(2018) Renuga D Rajaram et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Physiological and pathophysiological role of reactive oxygen species and reactive nitrogen species in the kidney

(2018) Yu Ishimoto et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes

(2018) Jay C. Jha et al.   CLINICAL SCIENCE

Impaired pressure natriuresis and non‐dipping blood pressure in Rats with early type 1 diabetes mellitus

(2018) Geoffrey J. Culshaw et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hypertension and Diabetes Mellitus

(2017) Alexander Staruschenko   HYPERTENSION

Synergistic Interaction of Hypertension and Diabetes in Promoting Kidney Injury and the Role of Endoplasmic Reticulum StressNovelty and Significance

(2017) Zhen Wang et al.   HYPERTENSION

Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure

(2017) Oleg Palygin et al.   Journal of the American Heart Association

Renal sodium transport in renin-deficient Dahl salt-sensitive rats

(2016) T. S. Pavlov et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Sodium Retention and Volume Expansion in Nephrotic Syndrome: Implications for Hypertension

(2015) Evan C. Ray et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Nox-4 and progressive kidney disease

(2015) Vicki Thallas-Bonke et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats

(2015) Allen W. Cowley et al.   HYPERTENSION

Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels

(2015) Daria V. Ilatovskaya et al.   Scientific Reports

Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy

(2014) J. C. Jha et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH Oxidase 4 Deficiency Reduces Aquaporin-2 mRNA Expression in Cultured Renal Collecting Duct Principal Cells via Increased PDE3 and PDE4 Activity

(2014) Eric Féraille et al.   PLoS One

Characterization of the development of renal injury in Type-1 diabetic Dahl salt-sensitive rats

(2013) Tiffani N. Slaughter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Deficiency of Renal Cortical EGF Increases ENaC Activity and Contributes to Salt-Sensitive Hypertension

(2013) T. S. Pavlov et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH Oxidases, Reactive Oxygen Species, and the Kidney: Friend and Foe

(2013) M. Sedeek et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1

(2012) Daria V. Ilatovskaya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The role of the epithelial Na+ channel (ENaC) in high AVP but low aldosterone states

(2012) James D. Stockand   Frontiers in Physiology

Hydrogen Peroxide Stimulates the Epithelial Sodium Channel through a Phosphatidylinositide 3-Kinase-dependent Pathway

(2011) He-Ping Ma   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyperglycemia and Renin-Dependent Hypertension Synergize to Model Diabetic Nephropathy

(2011) B. R. Conway et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Modulation of Pressure-Natriuresis by Renal Medullary Reactive Oxygen Species and Nitric Oxide

(2010) Paul M. O’Connor et al.   CURRENT HYPERTENSION REPORTS

Effects of Renal Perfusion Pressure on Renal Medullary Hydrogen Peroxide and Nitric Oxide Production

(2009) Chunhua Jin et al.   HYPERTENSION

Aberrant ENaC activation in Dahl salt-sensitive rats

(2009) Yutaka Kakizoe et al.   JOURNAL OF HYPERTENSION

NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension

(2008) Niu Tian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

p66shcInhibits Pro-survival Epidermal Growth Factor Receptor/ERK Signaling during Severe Oxidative Stress in Mouse Renal Proximal Tubule Cells

(2008) Istvan Arany et al.   JOURNAL OF BIOLOGICAL CHEMISTRY