Vaccination against SARS-CoV-2 and disease enhancement – knowns and unknowns

Data sharing for novel coronavirus (COVID-19)

(2020) Vasee Moorthy et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The Challenges of Vaccine Development against a New Virus during a Pandemic

(2020) Michael S. Diamond et al.   Cell Host & Microbe

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

SARS-CoV-2: a storm is raging

(2020) Savannah F. Pedersen et al.   JOURNAL OF CLINICAL INVESTIGATION

Hyperinflammatory shock in children during COVID-19 pandemic

(2020) Shelley Riphagen et al.   LANCET

Don’t rush to deploy COVID-19 vaccines and drugs without sufficient safety guarantees

(2020) Shibo Jiang   NATURE

Labs rush to study coronavirus in transgenic animals — some are in short supply

(2020) Ewen Callaway   NATURE

Rapid COVID-19 vaccine development

(2020) Barney S. Graham   SCIENCE

Development of an inactivated vaccine candidate for SARS-CoV-2

(2020) Qiang Gao et al.   SCIENCE

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

(2020) Jingyou Yu et al.   SCIENCE

Covid-19: risk factors for severe disease and death

(2020) Rachel E Jordan et al.   BMJ-British Medical Journal

A highly immunogenic, protective and safe adenovirus-based vaccine expressing MERS-CoV S1-CD40L fusion protein in transgenic human DPP4 mouse model

(2019) Anwar M Hashem et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

(2019) Tracy J. Ruckwardt et al.   IMMUNITY

A review of Dengvaxia®: development to deployment

(2019) Stephen J. Thomas et al.   Human Vaccines & Immunotherapeutics

Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy

(2018) Saranya Sridhar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines

(2018) Giuseppe Del Giudice et al.   SEMINARS IN IMMUNOLOGY

New Vaccine Technologies to Combat Outbreak Situations

(2018) Susanne Rauch et al.   Frontiers in Immunology

Vaccine confidence plummets in the Philippines following dengue vaccine scare: why it matters to pandemic preparedness

(2018) Heidi J Larson et al.   Human Vaccines & Immunotherapeutics

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus

(2016) Anurodh Shankar Agrawal et al.   Human Vaccines & Immunotherapeutics

A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates

(2015) Karuppiah Muthumani et al.   Science Translational Medicine

Advax™, a novel microcrystalline polysaccharide particle engineered from delta inulin, provides robust adjuvant potency together with tolerability and safety

(2015) Nikolai Petrovsky et al.   VACCINE

Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus

(2015) Troy C. Sutton et al.   VIROLOGY

Evaluation of candidate vaccine approaches for MERS-CoV

(2015) Lingshu Wang et al.   Nature Communications

Animal models for SARS and MERS coronaviruses

(2015) Lisa M Gretebeck et al.   Current Opinion in Virology

Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoV

(2014) F. Yasui et al.   JOURNAL OF IMMUNOLOGY

T Cell Responses to Whole SARS Coronavirus in Humans

(2014) C. K.-f. Li et al.   JOURNAL OF IMMUNOLOGY

Effects of Toll-Like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c Mice Immunized with UV-Inactivated Severe Acute Respiratory Syndrome-Related Coronavirus Vaccine

(2014) N. Iwata-Yoshikawa et al.   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome-Associated Coronavirus Vaccines Formulated with Delta Inulin Adjuvants Provide Enhanced Protection while Ameliorating Lung Eosinophilic Immunopathology

(2014) Yoshikazu Honda-Okubo et al.   JOURNAL OF VIROLOGY

Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus Infection

(2014) R. Channappanavar et al.   JOURNAL OF VIROLOGY

Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection

(2013) Maria G. Guzman et al.   ARCHIVES OF VIROLOGY

Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

(2012) Chien-Te Tseng et al.   PLoS One

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

(2011) M. Bolles et al.   JOURNAL OF VIROLOGY

T Cell Responses Are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice

(2010) J. Zhao et al.   JOURNAL OF VIROLOGY

Immunogenicity and Protective Efficacy in Mice and Hamsters of a β-Propiolactone Inactivated Whole Virus SARS-CoV Vaccine

(2010) Anjeanette Roberts et al.   VIRAL IMMUNOLOGY

Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines

(2008) R. H. See et al.   JOURNAL OF GENERAL VIROLOGY

A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters

(2008) E. W. Lamirande et al.   JOURNAL OF VIROLOGY

Vaccine-induced enhancement of viral infections

(2008) W. Huisman et al.   VACCINE