Infliximab in young paediatric IBD patients: it is all about the dosing

Development of Infliximab Target Concentrations during Induction in Pediatric Crohnʼs Disease Patients

(2019) Kathryn Clarkston et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

(2019) Nicholas A Kennedy et al.   Lancet Gastroenterology & Hepatology

Clinical Pharmacokinetics and Pharmacodynamics of Infliximab in the Treatment of Inflammatory Bowel Disease

(2018) Amy Hemperly et al.   CLINICAL PHARMACOKINETICS

Higher Infliximab Levels Are Not Associated With an Increase in Adverse Events in Inflammatory Bowel Disease

(2018) Tomer Greener et al.   INFLAMMATORY BOWEL DISEASES

Association Between Infliximab Drug and Antibody Levels and Therapy Outcome in Pediatric Inflammatory Bowel Diseases

(2018) Bella Ungar et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Long-term Outcomes of Infliximab Use for Pediatric Crohn Disease

(2018) Jennifer C. deBruyn et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Success and safety of high infliximab trough levels in inflammatory bowel disease

(2018) David Drobne et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Higher Infliximab Trough Levels Are Associated With Better Outcome in Paediatric Patients With Inflammatory Bowel Disease

(2018) Karen van Hoeve et al.   Journal of Crohns & Colitis

Therapeutic drug monitoring of anti-TNF therapy in children with inflammatory bowel disease

(2017) Karen van Hoeve et al.   Expert Opinion On Drug Safety

Clinical Use of Infliximab Trough Levels and Antibodies to Infliximab in Pediatric Patients With Inflammatory Bowel Disease

(2017) Laura Merras-Salmio et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Application of Population Pharmacokinetic Modeling for Individualized Infliximab Dosing Strategies in Crohn Disease

(2017) Adam Frymoyer et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Serum trough infliximab levels: A comparison of three different immunoassays for the monitoring of CT-P13 (infliximab) treatment in patients with inflammatory bowel disease

(2016) Karin Malíčková et al.   BIOLOGICALS

Optimizing Anti-TNF-α Therapy: Serum Levels of Infliximab and Adalimumab Are Associated With Mucosal Healing in Patients With Inflammatory Bowel Diseases

(2016) Bella Ungar et al.   Clinical Gastroenterology and Hepatology

Infliximab Dosing Strategies and Predicted Trough Exposure in Children With Crohn Disease

(2016) Adam Frymoyer et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Detection of anti-infliximab antibodies is impacted by antibody titer, infliximab level and IgG4 antibodies: a systematic comparison of three different assays

(2016) Joana Afonso et al.   Therapeutic Advances in Gastroenterology

Trough Concentrations of Infliximab Guide Dosing for Patients With Inflammatory Bowel Disease

(2015) Niels Vande Casteele et al.   GASTROENTEROLOGY

Antibodies to Infliximab Are Associated with Lower Infliximab Levels and Increased Likelihood of Surgery in Pediatric IBD

(2015) Naamah L. Zitomersky et al.   INFLAMMATORY BOWEL DISEASES

Changes in Serum Trough Levels of Infliximab During Treatment Intensification but not in Anti-infliximab Antibody Detection are Associated with Clinical Outcomes after Therapeutic Failure in Crohn's Disease

(2015) C. Steenholdt et al.   Journal of Crohns & Colitis

Patient Factors That Increase Infliximab Clearance and Shorten Half-life in Inflammatory Bowel Disease

(2014) Iris Dotan et al.   INFLAMMATORY BOWEL DISEASES

Early Infliximab Trough Levels Are Associated with Persistent Remission in Pediatric Patients with Inflammatory Bowel Disease

(2014) Namita Singh et al.   INFLAMMATORY BOWEL DISEASES

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease

(2014) F.M. Ruemmele et al.   Journal of Crohns & Colitis

Infliximab Therapy in Pediatric Patients 7 Years of Age and Younger

(2014) Judith R. Kelsen et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Detection of infliximab levels and anti-infliximab antibodies: a comparison of three different assays

(2012) N. Vande Casteele et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Infliximab trough levels may predict sustained response to infliximab in patients with Crohn's disease

(2012) Martin Bortlik et al.   Journal of Crohns & Colitis

Rational development and utilization of antibody-based therapeutic proteins in pediatrics

(2012) Zhenhua Xu et al.   PHARMACOLOGY & THERAPEUTICS

Assessing Response and Loss of Response to Biological Therapies in IBD

(2011) Henit Yanai et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Pharmacokinetic Properties of Infliximab in Children and Adults with Crohn's Disease: A Retrospective Analysis of Data from 2 Phase III Clinical Trials

(2011) Adedigbo A. Fasanmade et al.   CLINICAL THERAPEUTICS

Health-related quality of life in paediatric patients with inflammatory bowel disease related to disease activity

(2011) Johanna Haapamäki et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Pediatric modification of the Montreal classification for inflammatory bowel disease

(2010) Arie Levine et al.   INFLAMMATORY BOWEL DISEASES

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

(2010) Jean Frédéric Colombel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis

(2009) Adedigbo A. Fasanmade et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY