Design, synthesis, and Structure–Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors

Title
Design, synthesis, and Structure–Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors
Authors
Keywords
Tropomyosin receptor kinase (Trk), Neurotrophic receptor tyrosine kinase gene (NTRK), Fusion, Inhibitor, Resistance, Mutation
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 203, Issue -, Pages 112552
Publisher
Elsevier BV
Online
2020-07-13
DOI
10.1016/j.ejmech.2020.112552

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