A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ‐aminobutyric acidergic anticonvulsant

Functional analysis of epilepsy‐associated variants in STXBP1/Munc18‐1 using humanized Caenorhabditis elegans

(2020) Bangfu Zhu et al.   EPILEPSIA

Validated animal models for antiseizure drug (ASD) discovery: Advantages and potential pitfalls in ASD screening

(2019) Melissa Barker-Haliski et al.   NEUROPHARMACOLOGY

Pharmacoresistance – Epidemiology, mechanisms, and impact on epilepsy treatment

(2019) Mubeen Janmohamed et al.   NEUROPHARMACOLOGY

Rare coding variants in genes encoding GABA A receptors in genetic generalised epilepsies: an exome-based case-control study

(2018) Patrick May et al.   LANCET NEUROLOGY

α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

(2018) Shi Quan Wong et al.   NEUROBIOLOGY OF DISEASE

A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action

(2018) Shi Quan Wong et al.   JOURNAL OF NEUROSCIENCE METHODS

The epidemiology of drug-resistant epilepsy: A systematic review and meta-analysis

(2018) Linda Kalilani et al.   EPILEPSIA

Neuroprotective effects of gabaergic phenols correlated with their pharmacological and antioxidant properties

(2017) Leticia Delgado-Marín et al.   LIFE SCIENCES

Animal Models of Seizures and Epilepsy: Past, Present, and Future Role for the Discovery of Antiseizure Drugs

(2017) Wolfgang Löscher   NEUROCHEMICAL RESEARCH

Timelines of translational science: From technology initiation to FDA approval

(2017) Laura M. McNamee et al.   PLoS One

A cellular and regulatory map of the GABAergic nervous system of C. elegans

(2016) Marie Gendrel et al.   eLife

Modulating Behavior in C. elegans Using Electroshock and Antiepileptic Drugs

(2016) Monica G. Risley et al.   PLoS One

Status epilepticus in adults

(2015) John P Betjemann et al.   LANCET NEUROLOGY

Epilepsy research methods update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms

(2015) Vincent T. Cunliffe et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

On the nature of seizure dynamics

(2014) Viktor K. Jirsa et al.   BRAIN

Zebrafish models for translational neuroscience research: from tank to bedside

(2014) Adam Michael Stewart et al.   TRENDS IN NEUROSCIENCES

Gabaergic Pharmacological Activity of Propofol Related Compounds as Possible Enhancers of General Anesthetics and Interaction with Membranes

(2013) G. N. Reiner et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

(2012) S. Baxendale et al.   Disease Models & Mechanisms

Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models

(2010) Nicole M. Rowley et al.   EPILEPSY RESEARCH

ARRIVE: new guidelines for reporting animal research

(2010) Gordon B. Drummond et al.   JOURNAL OF PHYSIOLOGY-LONDON

A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans

(2010) Andrew R Burns et al.   Nature Chemical Biology

Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans

(2010) Rakesh Pandey et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for δ-GABAAreceptors

(2009) Murray B. Herd et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Lipophilicity of some GABAergic phenols and related compounds determined by HPLC and partition coefficients in different systems

(2009) Gabriela N. Reiner et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A Neuronal Acetylcholine Receptor Regulates the Balance of Muscle Excitation and Inhibition in Caenorhabditis elegans

(2009) Maelle Jospin et al.   PLOS BIOLOGY

Developmental maturation of synaptic and extrasynaptic GABAAreceptors in mouse thalamic ventrobasal neurones

(2007) Dianne R. Peden et al.   JOURNAL OF PHYSIOLOGY-LONDON

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols