Article
Obstetrics & Gynecology
Simona Anzhel, Sirpa Makinen, Helena Tinkanen, Tiina Mikkila, Anni Haltia, Antti Perheentupa, Candido Tomas, Hannu Martikainen, Aila Tiitinen, Juha S. Tapanainen, Zdravka Veleva
Summary: The quality of embryos transferred and the presence of tubal factor infertility affect the risk of ectopic pregnancy after IVF/ICSI. Transfer of top-quality embryos is associated with a lower rate of ectopic pregnancy. To reduce the risk of ectopic pregnancy, the number of embryos transferred should be minimized.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Environmental Sciences
Fei Liu, Ying Zhang, Fan Wang
Summary: This study exposed zebrafish embryos to TCS and evaluated its developmental toxicity. The results showed that TCS can induce oxidative stress and apoptosis, potentially through the ROS-p53-caspase dependent pathway.
ENVIRONMENTAL TOXICOLOGY
(2022)
Article
Environmental Sciences
Monike Felipe Gomes, Vinicius de Carvalho Soares de Paula, Lucia Regina Rocha Martins, Juan Ramon Esquivel Garcia, Flavia Yoshie Yamamoto, Adriane Martins de Freitas
Summary: The study assessed the toxicity of triclosan, triclocarban, and their binary mixture on catfish embryos at environmentally relevant concentrations. The results showed potential toxicity of these chemicals even at low concentrations and short exposure periods.
Review
Public, Environmental & Occupational Health
Jiani Liu, Danrong Chen, Yanqiu Huang, Francis Manyori Bigambo, Ting Chen, Xu Wang
Summary: The meta-analysis results indicated that maternal exposure to TCS during pregnancy was not significantly associated with neonatal birth weight, and children's urinary TCS level was also unrelated to children's BMI.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Raiza Paul, Alejandro Romero, Julia Molto, Nuria Ortuno, Jon Aizpurua, Maria Jose Gomez-Torres
Summary: This study examines the relationship between paternal exposure to dioxin-like polychlorinated biphenyls (DL-PCBs) and in vitro fertilization (IVF) outcomes. The findings suggest that serum DL-PCB concentrations are associated with embryo quality, implantation rates, clinical pregnancy likelihood, and live birth rates.
ENVIRONMENTAL RESEARCH
(2022)
Article
Obstetrics & Gynecology
Michael S. Awadalla, Nicole L. Vestal, Lynda K. McGinnis, Ali Ahmady, Richard J. Paulson
Summary: The study found that for women of all ages, the sustained implantation rates for day 5 good quality blastocysts were higher than for day 5 fair, day 5 poor, and day 6 blastocysts. There were also higher sustained implantation rates for younger patients compared to older patients when controlling for morphology and day of biopsy, showing that age plays a significant role in the success of implantation.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Review
Endocrinology & Metabolism
Ruxin Wang, Haixia Huang, Yong Tan, Guicheng Xia
Summary: This study aimed to explore the efficacy of atosiban on pregnancy outcomes in patients with repeated embryo implantation failure who underwent in vitro fertilization-embryo transfer (IVF-ET). A systematic search of English and Chinese databases found that atosiban was associated with a higher clinical pregnancy rate in patients with repeated implantation failure. However, more thorough and larger prospective randomized controlled studies are needed to confirm this conclusion.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Environmental Sciences
Xueqian Ma, Long Cui, Lin Chen, Jun Zhang, Xiaohui Zhang, Quanmin Kang, Fan Jin, Yinghui Ye
Summary: This study found that maternal plasma concentrations of perfluorooctanoic acid (PFOA) were negatively associated with the numbers of retrieved oocytes, mature oocytes, 2 PN zygotes, and good-quality embryos, while higher paternal plasma PFOA concentrations were significantly associated with reduced numbers of 2 PN zygotes. However, none of the maternal or paternal PFAS were significantly associated with the probability of implantation, clinical pregnancy, or live birth.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Caitlin R. Sacha, Irene Souter, Paige L. Williams, Jorge E. Chavarro, Jennifer Ford, Shruthi Mahalingaiah, Patricia K. Donahoe, Russ Hauser, David Pepin, Lidia Minguez-Alarcon
Summary: This study found a negative association between urinary concentrations of certain phthalate metabolites and follicular fluid anti-Mullerian hormone concentrations in women undergoing fertility treatment, which may have implications for antral follicle recruitment and fertility treatment outcomes.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Biochemistry & Molecular Biology
Manizha Shekibi, Sophea Heng, Guiying Nie
Summary: The development of endometrial receptivity is crucial for successful embryo implantation and pregnancy initiation. Recent studies have focused on the role of microRNAs (miRNAs) in the regulation of endometrial receptivity. This review provides an up-to-date knowledge of the miRNAs identified in humans and mice that may play a functional role in the establishment of receptivity. The findings suggest that miRNAs could be potential biomarkers and therapeutic targets for improving endometrial receptivity in human fertility treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Dongfeng Yang, Sifang Kong, Feng Wang, Lap Ah Tse, Zhi Tang, Yang Zhao, Chun Li, Minhui Li, Zihan Li, Shaoyou Lu
Summary: Urinary concentrations of TCS in a general adult population in South China were relatively low, with most individuals having a low health risk. There were no significant differences in TCS concentrations between sexes and education levels, but marital status and age may have a positive influence. After adjusting for BMI, age was found to be positively associated with TCS concentrations, particularly in the age group from 31 to 51 years old. This study provides baseline data on urinary TCS exposure in South China.
ENVIRONMENTAL POLLUTION
(2021)
Article
Obstetrics & Gynecology
He Li, Xiaoxi Sun, Junyi Yang, Lu Li, Wenbi Zhang, Xiang Lu, Junling Chen, Hua Chen, Min Yu, Wei Fu, Xiandong Peng, Jiazhou Chen, Ernest Hung Yu Ng
Summary: The study compared immediate and delayed frozen embryo transfers following a stimulated IVF cycle and found that immediate FET resulted in significantly higher ongoing pregnancy and live birth rates. This suggests that immediate FET may be more effective after a stimulated IVF cycle.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Sophea Heng, Nirukshi Samarajeewa, Asma Aberkane, Wafaa Essahib, Hilde Van de Velde, Maxine Scelwyn, M. Louise Hull, Beverley Vollenhoven, Luk J. Rombauts, Guiying Nie
Summary: This study found that PCX inhibits embryo implantation in vitro and in IVF patients. High levels of PCX significantly inhibited blastocyst attachment and penetration. The presence of PCX in the luminal epithelium was negatively associated with the success rate of clinical pregnancy.
FERTILITY AND STERILITY
(2021)
Article
Medicine, General & Internal
Yun Sun, Linlin Cui, Yao Lu, Jichun Tan, Xi Dong, Tianxiang Ni, Junhao Yan, Yichun Guan, Guimin Hao, Jia-Yin Liu, Bo Zhang, Daimin Wei, Yan Hong, Yaqiong He, Jia Qi, Bing Xu, Juanjuan Lu, Qian Zhang, Shanshan Zhao, Xiaowei Ji, Xiaofang Du, Jie Zhang, Jinyong Liu, Jing Wang, Yingqin Huang, Dongmei Huang, Yanzhi Du, Hugo Vankelecom, Heping Zhang, Zi-jiang Chen
Summary: Prednisone treatment does not improve live birth rate in patients with recurrent implantation failure compared to placebo. The use of prednisone may increase the risk of preterm delivery and biochemical pregnancy loss. These findings challenge the value of prednisone use in clinical practice for the treatment of recurrent implantation failure.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Environmental Sciences
Sara E. Gallego R, Gustavo A. Penuela, Emma Martinez-Lopez
Summary: The study found that ibuprofen and triclosan at concentrations of 25 and 50 μg/L can affect P. magdaleniatum, interfering with the activity of certain enzymes. The quantification of ibuprofen and triclosan concentrations in P. magdaleniatum muscle samples from different markets along the main rivers of Colombia revealed that triclosan levels in some sampling points during the dry season may lead to enzyme-level alterations in this species.
Review
Environmental Sciences
Malgorzata Waclawik, Wojciech Rodzaj, Bartosz Wielgomas
Summary: Researchers have shown an increasing interest in tracking personal exposure to multiple chemicals over time. Silicone wristbands have emerged as a valuable tool for assessing chemical risks in various environments. However, there is a lack of detailed information on the methods and a comprehensive comparison with other approaches. This review summarizes the current research using silicone wristbands as passive samplers, discusses the steps involved in obtaining exposure data, compares the characteristics of wristbands with other matrices for exposure assessment, and highlights the future research needs.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Aleksandra Stec, Joanna Jonca, Krzysztof Waleron, Malgorzata Waleron, Agata Ploska, Leszek Kalinowski, Bartosz Wielgomas, Szymon Dziomba
Summary: This study isolated EVs from Pectobacterium zantedeschiae culture media using different ultracentrifugation techniques and characterized them using BCA, NTA, and CE. The results showed that there was a satisfactory correlation between quantitative results obtained with BCA, NTA, and CE only for isolates obtained with the IDGUC. Moreover, NTA was found to be unable to provide reliable information on EVs quantity in samples isolated with UC and ICUC.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Environmental Sciences
Dorota Szczesna, Katarzyna Wieczorek, Joanna Jurewicz
Summary: Widespread exposure to persistent pollutants such as metals, pesticides, and chemicals can increase the risk of endometriosis. A review of relevant studies from the past 10 years found consistent evidence linking exposure to endocrine-disrupting chemicals (EDCs) like PCBs and OCPs with the development of endometriosis. The findings suggest that certain EDCs, including PCBs, OCPs, PBDEs, PFAS, and lead, contribute to the increased risk of endometriosis.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Agnieszka Wojtecka, Olga Kalinowska-Beszczynska, Anna Tyranska-Fobke, Dorota Kaleta, Malgorzata Wojnarowska, Marlena Robakowska, Lukasz Balwicki
Summary: Scholars and policymakers agree that more efforts should be made to reduce smoking and prevent nicotine use, especially among vulnerable adolescents. Surprisingly, in Poland, about 51% of children had their first contact with smoking at the age of 15 and older, despite the well-known health consequences. This research aims to investigate motivations, usage patterns, perceptions, and attitudes towards smoking/vaping and nicotine addiction among Polish youth. Through qualitative focus-group interviews with smokers and non-smokers aged 16-18, the study uncovers strategies used by adolescents to overcome financial barriers and avoid anti-smoking messages on packaging, providing new insights.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Biochemical Research Methods
Anna Klimowska, Evelien Wynendaele, Bartosz Wielgomas
Summary: The aim of this study was to develop an analytical method for quantifying and assessing the stability of 26 phenolic and acidic biomarkers of environmental pollutants in human urine. The method involved solid-phase extraction coupled with gas chromatography and tandem mass spectrometry (SPE-GC/MS/MS). The results showed satisfactory accuracy, precision, and limits of quantification for the biomarkers, and the method was successfully used for quantification in 38 urine samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Pharmacology & Pharmacy
Anna Hering, Justyna Stefanowicz-Hajduk, Magdalena Gucwa, Bartosz Wielgomas, Jadwiga Renata Ochocka
Summary: This study investigated the biological effects of fermented honeybush extracts, which are derived from an African shrub known for its high polyphenol content. The extracts were found to inhibit certain enzymes responsible for skin malfunction and aging, such as collagenase, elastase, tyrosinase, and hyaluronidase. The extracts also demonstrated potential for wound healing and sun protection, as well as strong antioxidant properties. These findings highlight the potential of honeybush extracts as anti-aging, anti-inflammatory, and skin-protective agents.
Article
Chemistry, Multidisciplinary
Hannah Hirmz, Frederick Verbeke, Bartosz Wielgomas, Christophe Furman, Emmanuelle Lipka, Bart De Spiegeleer, Evelien Wynendaele
Summary: Green chemistry initially focused on organic synthetic approaches, and now green analytics is also seeking ways to reduce volumes, cost, and ecotoxicity of analytically used chemicals and lower energy usage. The current emphasis is on techniques like miniaturization, on-line spectroscopy, and chemicals used in the analytical process. However, little attention has been given to the production and use of analytical reagents in greening analytics.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Engineering, Environmental
Ivan Liakh, Darya Harshkova, Pavel Hrouzek, Katerina Bisova, Anna Aksmann, Bartosz Wielgomas
Summary: The use of unicellular algae for removing xenobiotics from wastewaters is a rapidly developing field in environmental protection. Efficient phycoremediation requires biosorption, bioaccumulation, and biotransformation. However, the potential toxicity of biotransformation products and the resistance of analyzed algae strains to the mixture of compounds need to be considered. In this study, Chlamydomonas reinhardtii showed promise in removing diclofenac, a non-steroidal anti-inflammatory drug, through biosorption, bioaccumulation, and biotransformation processes.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Anna Merecz-Sadowska, Przemyslaw Sitarek, Tomasz Kowalczyk, Marcin Palusiak, Marta Hoelm, Karolina Zajdel, Radoslaw Zajdel
Summary: This study assessed the antioxidant and anti-inflammatory properties of Leonurus sibiricus L. transgenic roots extracts. The results showed that these extracts contain active components with potential antioxidant and anti-inflammatory effects. In particular, the extract containing AtPAP1 transcriptional factor demonstrated superior activities.
Review
Nutrition & Dietetics
Anna Merecz-Sadowska, Przemyslaw Sitarek, Tomasz Kowalczyk, Karolina Zajdel, Mariusz Jecek, Pawel Nowak, Radoslaw Zajdel
Summary: Anthocyanins are flavonoid compounds found in fruits and vegetables, which contribute to their color and offer various health benefits due to their biological properties. Malvidin, one of the most well-known anthocyanidins, and its glycosides have been shown in multiple studies to possess anti-carcinogenic, diabetes-control, cardiovascular-disease-prevention, and brain-function-improvement properties. These health benefits are primarily attributed to their antioxidant and anti-inflammatory effects, which are influenced by the modulation of critical genes. This article reviews the biological activity of malvidin and its glycosides and their role in promoting health.
Article
Multidisciplinary Sciences
Adam Darago, Michal Klimczak, Joanna Jurewicz, Malgorzata Kucharska, Anna Kilanowicz
Summary: There is a steady increase in shooting practices worldwide and lead exposure at shooting ranges poses a risk to employees and users, particularly in Poland where it is not widely reported. This study aimed to assess lead exposure in selected indoor shooting ranges in central Poland and found that airborne lead concentrations exceeded the occupational exposure limit. Those participating in shooting, even for a few hours per week, showed elevated blood and urine lead levels and decreased ALA-D activity. This indicates an elevated risk for adverse health effects and suggests the need for information on health consequences and biomonitoring at these sites.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Pawel Mroczkowski, Lukasz Dziki, Tereza Vosikova, Ronny Otto, Anna Merecz-Sadowska, Radoslaw Zajdel, Karolina Zajdel, Hans Lippert, Olof Jannasch
Summary: This study examines the number of lymph nodes removed during rectal cancer surgery and the validity of the commonly recommended minimum of 12 nodes. Factors such as age, gender, and pre-therapeutic stage can affect the number of nodes removed. The study found that the probability of finding a positive lymph node increased with the number of nodes examined.
Article
Environmental Sciences
Pawel Radwan, Bartosz Wielgomas, Michal Radwan, Rafal Krasinski, Stella Bujak-Pietrek, Kinga Polanska, Anna Kilanowicz, Joanna Jurewicz
Summary: This study investigates the relationship between exposure to parabens and benzophenones, commonly found in cosmetics, and female reproductive health. It found that increased exposure to butyl paraben was associated with a significant decrease in MII oocyte count, while exposure to high levels of benzophenone-3 also decreased MII oocyte count. However, exposure to other parabens and benzophenone-3 were not related to any of the examined reproductive outcomes.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Meeting Abstract
Public, Environmental & Occupational Health
A. Tyranska-Fobke, L. Balwicki, D. Kaleta, M. Goniewicz, G. Juszczyk
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2022)
