Article
Environmental Sciences
Zhuang Wang, Fan Zhang, De-Gao Wang
Summary: A new method for predicting the joint toxicity of chemical pollutants was proposed, which integrated a mixture descriptor with an established mixture toxicology method. The results showed that this method provided more accurate predictions compared to traditional models.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Engineering, Environmental
Xianglin Liu, Xiaowei Zheng, Liangliang Zhang, Jue Li, Yanyao Li, Honghui Huang, Zhengqiu Fan
Summary: This study investigated the toxicity mechanisms of emerging PFAS mixtures to aquatic organisms. The results showed that PFAS mixture had a significant growth inhibitory effect on algae at environmental concentration, and the toxicity was stronger than that of individual PFAS, demonstrating a synergistic effect. The joint toxicity mechanisms involved damage to the photosynthetic system, obstruction of ROS metabolism, and inhibition of DNA replication.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Toxicology
Sanjeeva J. Wijeyesakere, Tyler Auernhammer, Amanda Parks, Dan Wilson
Summary: We developed a mechanistic machine-learning model to predict mammalian acute oral toxicity. The model was trained using a rat toxicity database and accurately predicted the oral LD50 of compounds. It showed high sensitivity and has potential applications in assessing highly toxic substances.
TOXICOLOGICAL SCIENCES
(2023)
Article
Environmental Sciences
Simon Hansul, Andreas Fettweis, Erik Smolders, Karel De Schamphelaere
Summary: The study tested the prediction of Cu-Ni-Zn mixture toxicity to Daphnia magna populations using the DEB-IBM model, finding that mixture effects were concentration and endpoint dependent. The DEB-IBM accurately predicted effects on 6-week density, including antagonistic effects at high concentrations, while initial population growth rate effects were more challenging to predict.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2021)
Article
Environmental Sciences
Giovanna J. Lavado, Diego Baderna, Domenico Gadaleta, Marta Ultre, Kunal Roy, Emilio Benfenati
Summary: Research interest in environmental toxicity assessment using T. platyurus has increased, but there are currently no computational models to predict acute toxicity in this organism. This study developed QSAR models for predicting acute toxicity in T. platyurus, following OECD principles and using advanced machine learning techniques to achieve promising statistical quality in the dataset.
Article
Environmental Sciences
Lu Lv, Wenhong Li, Xinfang Li, Dou Wang, Hongbiao Weng, Yu-Cheng Zhu, Yanhua Wang
Summary: Pesticide exposure remains a significant factor in the decline of insect pollinators. It is necessary to assess the effects of mixtures on pollinator risk assessments due to their frequent exposure to multiple agrochemicals. This study explored the toxic effects of a mixture of thiacloprid and cyproconazole on honey bees and found that the combination exhibited acute synergistic effects and disrupted the physiological homeostasis of honey bees.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Yanhua Wang, Lu Lv, Chao Xu, Dou Wang, Guiling Yang, Xinquan Wang, Hongbiao Weng, Qiang Wang
Summary: The study found that the mixture of thiophanate-methyl and fenvalerate showed higher toxicity to zebrafish embryos compared to individual chemicals, and had a greater impact on the expression of related genes in zebrafish. Therefore, future environmental risk assessments need to consider the effects of pesticide mixtures on aquatic ecosystems.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Management
Gianluca Biggi, Elisa Giuliani, Arianna Martinelli, Emilio Benfenati
Summary: Researchers propose a method that combines patent analysis with computational toxicology to measure the chemical toxicity components within patents. By analyzing the toxicity of ten hazardous chemicals and comparing them with other groups of chemical patents, they suggest that this method could have significant policy implications for future research.
Article
Environmental Sciences
Tao Cang, Yancen Lou, Yu-Cheng Zhu, Wenhong Li, Hongbiao Weng, Lu Lv, Yanhua Wang
Summary: The extensive use of pesticides negatively affects insect pollinators' health, yet few studies have examined the toxic impacts of pesticide combinations on them. This study aimed to investigate the combined effects of tetrachlorantraniliprole (TET) and tebuconazole (TEB) on honey bees. The results showed that TET had higher toxicity to honey bees compared to TEB. The mixture of TET and TEB exhibited acute synergistic toxicity to the pollinators, affecting their immune response and detoxification metabolism. These findings provide insights into the complex toxic mechanisms of pesticide mixtures on honey bees and can inform pesticide regulation strategies to protect honey bee populations.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Yanhua Wang, Zhongwen Gao, Chuande Liu, Liangang Mao, Xinju Liu, Jindong Ren, Zeqi Lu, Jie Yao, Xuan Liu
Summary: The present study aimed to clarify the combined toxic impacts of pyraclostrobine (PYR) and metiram (MET) on zebrafish. Results showed that the LC50 values of MET and PYR for fish embryos were 0.0025 mg a.i. L-1 and 0.019 mg a.i. L-1, respectively. The combination of PYR and MET had a synergistic impact on fish embryos, leading to increased levels of POD, CYP450, and VTG. The frequent application of these pesticides may pose a potential ecotoxicological hazard to aquatic ecosystems.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Nicole M. Dennis, Seenivasan Subbiah, Adcharee Karnjanapiboonwong, Michael L. Dennis, Chris McCarthy, Christopher J. Salice, Todd A. Anderson
Summary: This study established species- and tissue-specific PFAS chronic toxicity values and compared them with previously reported toxicity reference values, revealing higher bioaccumulation factors in birds exposed via water and suggesting a comprehensive examination of all probable sources of oral exposure for accurate derivation of toxicity reference values for ecological risk assessment in the future.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2021)
Article
Engineering, Environmental
Mainak Chatterjee, Kunal Roy
Summary: This study developed three different mixture-Quantitative Structure-Activity Relationship (mixture-QSAR) models for three different bacterial species. Interspecies modeling was explored to find inter-correlation among the toxicity of the studied organisms, and quantitative structure activity-activity relationship (QSAAR) models were developed. All the models were validated using internal and external validation tests as suggested in the OECD guidelines.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Food Science & Technology
T. Tralau, M. Oelgeschlager, J. Kugler, D. Bloch, A. Braeuning, T. Burgdorf, P. Marx-Stoelting, V Ritz, S. Schmeisser, A. Trubiroha, S. Zellmer, A. Luch, G. Schoenfelder, R. Solecki, A. Hensel
Summary: Current legislation mainly focuses on the toxicological evaluation of single substances, lacking measures for the regulation of chemical mixtures. Researchers propose a proactive approach using the exposome concept and large-scale hazard screens to identify chemicals in mixtures and predict potential health risks. They suggest generating co-exposure patterns for specific consumer groups to assess the risk of identified mixtures, especially those from food, medicine, and cleaning products.
Article
Marine & Freshwater Biology
Lauren Zink, Steve Wiseman, Gregory G. Pyle
Summary: This study found that microplastics and metals are commonly found contaminants in freshwater systems worldwide. The interaction between microplastics and cadmium poses potential threats to the health of Nephelopsis obscura, a predatory leech species. The study revealed that sediment can protect against cadmium uptake and that cadmium is more readily accumulated from waterborne sources. After exposure to cadmium, microplastics, and their mixture, leeches showed decreased concentrations of serotonin and impaired feeding behaviors. While leeches were able to recover from microplastic toxicity within a week, cadmium toxicity persisted.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Mainak Chatterjee, Kunal Roy
Summary: This study developed a quantitative structure-activity relationship (QSAR) model to assess the environmental risk of pharmaceutical and pesticide mixtures. The developed partial least squares (PLS) model was rigorously validated and proved to be reliable and highly predictive.
Review
Chemistry, Multidisciplinary
M. Sigurnjak Bures, M. Cvetnic, M. Miloloza, D. Kucic Grgic, M. Markic, H. Kusic, T. Bolanca, M. Rogosic, S. Ukic
Summary: The presence of contaminants in natural waters poses a potential threat to the environment, especially in multi-component systems where interactions can lead to varying levels of toxicity. While experimental determination of toxicity in multi-component systems is possible, utilizing predictive models is faster, more environmentally friendly, and cost-effective. Conventional models like concentration addition and independent action models are still widely used, but integrated models offer greater accuracy despite requiring more data. Advanced numerical methods like genetic algorithms, neural networks, and fuzzy set theory are providing new perspectives on toxicity prediction, although a universal tool for toxicity assessment has not yet been developed.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Article
Spectroscopy
L. Mikac, E. Kovacevic, S. Ukic, M. Raic, T. Jurkin, I. Maric, M. Gotic, M. Ivanda
Summary: Excessive use of pesticides disrupts the natural balance in the environment, leading to water and food contamination. Fast, robust, and cost effective monitoring techniques are necessary for the detection of pesticides. In this study, surface-enhanced Raman spectroscopy (SERS) was used successfully to detect four common pesticides, demonstrating its potential for detecting analytes at low concentrations.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biotechnology & Applied Microbiology
D. Kucic Grgic, M. Miloloza, E. Lovrincic, A. Kovacevic, M. Cvetnic, V. Ocelic Bulatovic, V Prevaric, K. Bule, S. Ukic, M. Markic, T. Bolanca
Summary: The study demonstrated that mixed bacterial cultures were more effective in degrading LDPE and PS microplastics compared to pure bacterial strains, with higher biodegradation efficiency observed for MP-LDPE than for MP-PS.
CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY
(2021)
Review
Chemistry, Multidisciplinary
Martina Miloloza, Matija Cvetnic, Dajana Kucic Grgic, Vesna Ocelic Bulatovic, Sime Ukic, Marko Rogosic, Dionysios Dion Dionysiou, Hrvoje Kusic, Tomislav Bolanca
Summary: Recent research has shown that microplastics, tiny plastic particles, are present everywhere and they have detrimental effects on organisms due to their tendency to bioaccumulate, hazardous additives, and the presence of other contaminants and pathogens on their surface. Biodegradation, though most plastics are not readily biodegradable, is a popular and cost-effective remediation technique that is environmentally friendly. Various bio-cultures such as bacteria, mold, yeast, and algae can be used for biodegradation, and there are analytical and microbiological methods available for monitoring the process. However, currently, no microbial method can completely remove microplastics from the environment within a reasonable time frame, leading to the combination of biodegradation with other methods such as membrane filtration.
ENVIRONMENTAL CHEMISTRY LETTERS
(2022)
Article
Polymer Science
Martina Miloloza, Kristina Bule, Viktorija Prevaric, Matija Cvetnic, Sime Ukic, Tomislav Bolanca, Dajana Kucic Grgic
Summary: This study tested the harmful effects of different types of microplastics on three different microorganisms. The results showed that all three microorganisms were potentially harmed by microplastics, and the harmfulness increased with higher concentrations of microplastics. The particle size of microplastics had varying effects on different microorganisms, with Saccharomyces cerevisiae being the most sensitive to microplastics.
Review
Chemistry, Analytical
Sime Ukic, Danijela Asperger, Tomislav Bolanca
Summary: This paper provides an overview of the development of chromatography in the Republic of Croatia and the role played by three institutions.
Article
Polymer Science
Martina Miloloza, Sime Ukic, Matija Cvetnic, Tomislav Bolanca, Dajana Kucic Grgic
Summary: Microplastics are a global environmental problem, and their biodegradation is an effective solution. This study investigates the optimal conditions for the biodegradation of microplastics by two bacteria and analyzes the process in detail.
Article
Chemistry, Analytical
Dajana Kucic Grgic, Martina Miloloza, Vesna Ocelic Bulatovic, Sime Ukic, Miroslav Slouf, Veronika Gajdosova
Summary: In this study, a microbial consortium was screened for its efficacy in degrading LDPE/TPS. The consortium was composed of bacteria and fungi isolated from activated sludge, river sediment, and compost. The experiments showed that the microorganisms were able to degrade polymeric materials, with the mixed culture completely degrading TPS. The weight loss and analysis results demonstrated that degradation was more intense in the experiment using microorganisms from compost.
Review
Chemistry, Analytical
Kristina Bule Mozar, Martina Miloloza, Viktorija Martinjak, Matija Cvetnic, Hrvoje Kusic, Tomislav Bolanca, Dajana Kucic Grgic, Sime Ukic
Summary: Microplastics have become recognized as an emerging environmental pollutant in the past two decades. Their small size allows them to enter the food chain easily, leading to adverse effects on organisms and the environment. Biodegradation is the most environmentally friendly and economically acceptable method, but it has drawbacks such as low removal rate and efficiency. Therefore, pretreatment with advanced oxidation processes (AOPs) can enhance the biodegradation of microplastics.
Review
Chemistry, Multidisciplinary
A. Tutic, M. Miloloza, M. Cvetnic, V. Martinjak, L. Furac, M. Markic, S. Ukic, T. Bolanca, D. Kucic Grgic
Summary: Coke production generates large amounts of complex wastewater, containing priority pollutants such as phenols, cyanides, and thiocyanates. Single treatment processes are insufficient, and a combination of physicochemical and biological treatment methods, with special emphasis on biological treatment, should be applied. This article provides a literature review of coking wastewater characteristics and treatment technologies, aiming to summarize the current knowledge and optimize existing solutions.
KEMIJA U INDUSTRIJI-JOURNAL OF CHEMISTS AND CHEMICAL ENGINEERS
(2023)
Article
Chemistry, Multidisciplinary
I Radic, M. Runje, M. Cvetnic, M. Haluzan, M-L Jelicic, M. Miloloza, D. Kucic Grgic, V Prevaric, S. Ukic, T. Bolanca
Summary: This study monitored and analyzed trace elements in Fosamprenavir calcium using ICP-MS and appropriate sample preparation method. By adding thiourea, the loss of osmium was successfully reduced, leading to improved accuracy and precision in the method.
KEMIJA U INDUSTRIJI-JOURNAL OF CHEMISTS AND CHEMICAL ENGINEERS
(2021)
Review
Environmental Sciences
Attila Csaba Kondor, Anna Viktoria Vancsik, Laszlo Bauer, Lili Szabo, Zoltan Szalai, Gergely Jakab, Gabor Maasz, Marta Pedrosa, Maria Jose Sampaio, Ana Rita Lado Ribeiro
Summary: This review provides a critical overview of research on the removal efficiency of priority substances and compounds of emerging concern through bank filtration, discussing influencing factors and future challenges. The findings show that the efficiency of bank filtration is influenced by multiple factors and varies for different substances.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinyan Wang, Shuai Zhang, Huihui Yan, Zhao Ma, Yunshan Zhang, Haining Luo, Xueli Yang
Summary: This study investigated the association between ambient PM2.5, O3 pollution, and ovarian reserve in reproductive-aged Chinese women. The results showed that increased exposure to PM2.5 and O3 was associated with decreased AMH levels, indicating reduced ovarian reserve. Notably, the effects of O3 exposure on ovarian reserve were different from those of PM2.5 exposure.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Tingting Ma, Yanjuan Ding, Fengjiao Xu, Chen Zhang, Min Zhou, Ya Tang, Yanrong Chen, Yating Wen, Rufei Chen, Bin Tang, Shigui Wang
Summary: The dragonfly species Orthetrum albistylum can accumulate heavy metals, and its heat shock protein genes have the potential to serve as biomarkers for monitoring environmental pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Naoto Ishiwaka, Koya Hashimoto, Masayoshi K. Hiraiwa, Francisco Sanchez-Bayo, Taku Kadoya, Daisuke Hayasaka
Summary: Systemic insecticides and rising temperatures have combined effects on the abundance of Odonata nymphs in paddy fields. The standalone effect of insecticide exposure decreased the Odonata community, while nymphs decreased synergistically with temperature rise in paddy water. However, the impacts of each stressor alone varied among species.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Marco Vecchiato, Carlo Barbante, Elena Barbaro, Francois Burgay, Warren R. L. Cairns, Alice Callegaro, David Cappelletti, Federico Dallo, Marianna D'Amico, Matteo Feltracco, Jean-Charles Gallet, Andrea Gambaro, Catherine Larose, Niccolo Maffezzoli, Mauro Mazzola, Ivan Sartorato, Federico Scoto, Clara Turetta, Massimiliano Varde, Zhiyong Xie, Andrea Spolaor
Summary: The Arctic region is facing contamination from long-range pollution and local human activities. Polycyclic Aromatic Hydrocarbons (PAHs) are used as environmental indicators for emission, transport, and deposition processes. Research conducted in the Arctic surface snow in Ny-Ålesund, Svalbard from October 2018 to May 2019 shows that long-range inputs of PAHs mainly occur in winter, while the most abundant analyte retene exhibits opposite seasonal trends.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Maoshui Zhuo, Zhijie Chen, Xiaoqing Liu, Wei Wei, Yansong Shen, Bing-Jie Ni
Summary: This paper discusses the application of three catalytic processes (photocatalysis, electrocatalysis, and biocatalysis) in the management of microplastic pollution, and introduces the efficiency and catalytic mechanisms of different catalysts. It also proposes the development prospects for sustainable management of microplastic pollution.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Shiyu Chen, Zhenzhen Shi, Qiang Zhang
Summary: In this study, a human physiologically based pharmacokinetic (PBPK) model of diethyl phthalate (DEP) was developed to assess its toxicity. The model considers the distribution and metabolism of DEP and its active metabolite monoethyl phthalate (MEP) in different tissue compartments. Sensitivity analysis and Bayesian Markov chain Monte Carlo (MCMC) simulations were performed to evaluate the uncertainty and variability of the model parameters. The results suggest that dermal absorption is an important route of exposure to DEP in the environment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Bangguo Wang, Lijing Wang, Wenxi Cen, Tao Lyu, Peter Jarvis, Yang Zhang, Yuanxun Zhang, Yinghui Han, Lei Wang, Gang Pan, Kaili Zhang, Wei Fan
Summary: This study investigates the feasibility and mechanisms of a chemical-free nanobubble-based AOP for treating organic micropollutants in water. The results show that the oxygen nanobubble AOP has a significantly higher removal efficiency compared to air and nitrogen nanobubbles. The treatment performance is not affected by pH and the presence of ions. Higher initial concentrations of the micropollutant lead to slower treatment processes, but similar removal performance is achieved in the end. The presence of organic matter reduces the removal rate of the micropollutant. The results have practical feasibility for water and wastewater treatment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yingmei Huang, Jicai Yi, Yao Huang, Songxiong Zhong, Bin Zhao, Jing Zhou, Yuxuan Wang, Yiwen Zhu, Yanhong Du, Fangbai Li
Summary: This study investigates the impact of biochar on methylmercury (MeHg) accumulation in rice. The results show that biochar reduces MeHg levels in paddy soils by decreasing bioavailable Hg and microbial Hg methylation. Additionally, biochar decreases the uptake and translocation of MeHg in rice plants, resulting in a reduction of MeHg accumulation in rice grains.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Nengde Zeng, Fei Huang, Jiani Du, Chenghao Huang, Qian Yang, Xinhua Zhan, Baoshan Xing
Summary: This study investigates the protein targets and protein-ligand interactions related to PAH contamination in crop xylem sap using computational tools. The results show that phenanthrene has a more pronounced effect on the xylem sap proteins of maize and wheat, with maize DEPs associated with lipid biosynthesis and wheat DEPs exhibiting an increase in ABC transporters. This study provides insights into the regulation and movement of PAHs within plant xylem.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinwei Chen, Hao Ma, Run Wang, Man Wang, Binbin Zhu, Yanqing Cong, Xiayue Zhu, Guoqin Wang, Yi Zhang
Summary: Co3O4/TiO2-NRs electrodes with excellent photoresponse were prepared via plasma-assisted modification of Co3O4 on TiO2. The combination of Co3O4 and TiO2 improved the light utilization efficiency and showed potential for degradation of pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Wenjing Ji, Liying Song, Jing Wang, Hongqing Song
Summary: This study conducted a life-cycle assessment to examine the correlation between natural gas consumption and carbon emissions in different end uses in China. The results showed that both natural gas consumption and life-cycle carbon emissions have been increasing since 2017. Significant variations in NG life-cycle carbon emissions were found across different provinces and sectors, highlighting the need for targeted efforts to reduce carbon emissions.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Youyi Chen, Boxuan Zhang, Pojun Zhang, Guogui Shi, Hao Liang, Wu Cai, Jingyu Gao, Sumin Zhuang, Kaiyin Luo, Jiaqi Zhu, Chaoxiang Chen, Kunyu Ma, Jinrong Chen, Chun Hu, Xueci Xing
Summary: The synergistic effects of trace sulfadiazine and cast-iron corrosion scales on the formation of disinfection by-products in drinking water distribution systems were investigated. The presence of magnetite resulted in increased concentrations of DBPs due to the higher microbial activity and enhanced microbial extracellular electron transport pathway. The study highlights the importance of considering trace antibiotics pollution and corrosion scales in water sources for DBP control.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Bishwa Raj Pokharel, Vijay Sheri, Manoj Kumar, Zhiyong Zhang, Baohong Zhang
Summary: This review summarizes the interactions, uptake, and transport of aluminum nanoparticles (Al-NPs) in plants, highlighting their negative effects on plant growth and development, as well as their potential to alter plant defense systems and gene expression.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yonglu Wang, Fengsong Zhang, Xiaoyong Liao, Xiao Yang, Guixiang Zhang, Liyun Zhang, Chaojun Wei, Pengge Shi, Jiongxin Wen, Xiaorong Ju, Can Xu, Yang Liu, Ying Lan
Summary: This study aims to explore the effects of thiencarbazone-methyl center dot isoxaflutole on soil microflora and the potential mitigation mechanisms to bacterial communities. It was found that increasing the application of thiencarbazone-methyl center dot isoxaflutole resulted in increased stress on soil bacterial community structure and diversity. Increasing soil pH was recognized as a key factor in improving the diversity and structure of soil microflora. Supplemental use of nitrapyrin or modified attapulgite can increase soil pH and improve bacterial diversity.
ENVIRONMENTAL POLLUTION
(2024)