Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study

Computational Study of Drugs Targeting Nuclear Receptors

(2020) Maša Kenda et al.   MOLECULES

ANALYSIS OF TRANSCRIPTIONAL RESPONSE IN ZEBRAFISH ELEUTHEROEMBRYOS EXPOSED TO CLIMBAZOLE: SIGNALING PATHWAYS AND POTENTIAL BIOMARKERS

(2019) Hui Zhang et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

P38/TRHr-Dependent Regulation of TPO in Thyroid Cells Contributes to the Hypothyroidism of Triclosan-Treated Rats

(2018) Pei Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effects of triclosan (TCS) on hormonal balance and genes of hypothalamus-pituitary- gonad axis of juvenile male Yellow River carp ( Cyprinus carpio )

(2018) Fan Wang et al.   CHEMOSPHERE

Triclosan Lacks (Anti-)Estrogenic Effects in Zebrafish Cells but Modulates Estrogen Response in Zebrafish Embryos

(2018) Hélène Serra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Evaluation of triclosan in the Hershberger and H295R steroidogenesis assays

(2018) W.T. Farmer et al.   TOXICOLOGY LETTERS

Impact of Triclosan on Female Reproduction through Reducing Thyroid Hormones to Suppress Hypothalamic Kisspeptin Neurons in Mice

(2018) Xin-Yuan Cao et al.   Frontiers in Molecular Neuroscience

The Florence Statement on Triclosan and Triclocarban

(2017) Rolf U. Halden et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Triclosan exposure, transformation, and human health effects

(2017) Lisa M. Weatherly et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Investigation of the presence and endocrine activities of pesticides found in wastewater effluent using yeast-based bioassays

(2017) Paul Westlund et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Improving the reliability of aquatic toxicity testing of hydrophobic chemicals via equilibrium passive dosing – A multiple trophic level case study on bromochlorophene

(2017) Felix Stibany et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effects of triclosan on hormones and reproductive axis in female Yellow River carp ( Cyprinus carpio ): Potential mechanisms underlying estrogen effect

(2017) Fan Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Downscaling procedures reduce chemical use in androgen receptor reporter gene assay

(2016) Carolina Di Paolo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Endocrine Disrupting Effects of Triclosan on the Placenta in Pregnant Rats

(2016) Yixing Feng et al.   PLoS One

VirtualToxLab™ - In silico prediction of the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. Two years and 2,000 compounds of experience: a progress report

(2016) Angelo Vedani   ALTEX-Alternatives to Animal Experimentation

Environmental chemicals active as human antiandrogens do not activate a stickleback androgen receptor but enhance a feminising effect of oestrogen in roach

(2015) Anke Lange et al.   AQUATIC TOXICOLOGY

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

(2015) A. C. Gore et al.   ENDOCRINE REVIEWS

Use of pooled samples to assess human exposure to parabens, benzophenone-3 and triclosan in Queensland, Australia

(2015) A.L. Heffernan et al.   ENVIRONMENT INTERNATIONAL

Chinese population exposure to triclosan and triclocarban as measured via human urine and nails

(2015) Jie Yin et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

Growth and migration of LNCaP prostate cancer cells are promoted by triclosan and benzophenone-1 via an androgen receptor signaling pathway

(2015) Seung-Hee Kim et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities

(2015) Katra Kolšek et al.   TOXICOLOGY IN VITRO

OpenVirtualToxLab—A platform for generating and exchanging in silico toxicity data

(2015) Angelo Vedani et al.   TOXICOLOGY LETTERS

Distribution of selected antiandrogens and pharmaceuticals in a highly impacted watershed

(2015) M.J. Arlos et al.   WATER RESEARCH

Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors

(2015) Marina Grimaldi et al.   Frontiers in Endocrinology

Methoxychlor and triclosan stimulates ovarian cancer growth by regulating cell cycle- and apoptosis-related genes via an estrogen receptor-dependent pathway

(2014) Joo-Young Kim et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Endocrine Disruptome—An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding

(2014) Katra Kolšek et al.   Journal of Chemical Information and Modeling

Determination of bisphenol A, triclosan and their metabolites in human urine using isotope-dilution liquid chromatography–tandem mass spectrometry

(2014) Gilles Provencher et al.   JOURNAL OF CHROMATOGRAPHY A

Are In Vitro Methods for the Detection of Endocrine Potentials in the Aquatic Environment Predictive for In Vivo Effects? Outcomes of the Projects SchussenAktiv and SchussenAktivplus in the Lake Constance Area, Germany

(2014) Anja Henneberg et al.   PLoS One

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway

(2014) Ruili Huang et al.   Scientific Reports

Prenatal Exposure to Environmental Phenols: Concentrations in Amniotic Fluid and Variability in Urinary Concentrations during Pregnancy

(2013) Claire Philippat et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effects of triclocarban,N,N-diethyl-meta-toluamide, and a mixture of pharmaceuticals and personal care products on fathead minnows (Pimephales promelas)

(2013) Jenny E. Zenobio et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Distinct Properties of Cell-Type-Specific and Shared Transcription Factor Binding Sites

(2013) Jason Gertz et al.   MOLECULAR CELL

Effects of triclocarban on the transcription of estrogen, androgen and aryl hydrocarbon receptor responsive genes in human breast cancer cells

(2013) Patrick Tarnow et al.   TOXICOLOGY IN VITRO

Hair Relaxer Use and Risk of Uterine Leiomyomata in African-American Women

(2012) L. A. Wise et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter

(2012) Natasha Thorne et al.   CHEMISTRY & BIOLOGY

Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels

(2012) Nils Helge Schebb et al.   CHEMOSPHERE

Effect directed analysis and mixture effects of estrogenic compounds in a sediment of the river Elbe

(2012) Sebastian Schmitt et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha

(2012) Mei-Fei Yueh et al.   PLoS One

VirtualToxLab — A platform for estimating the toxic potential of drugs, chemicals and natural products

(2012) Angelo Vedani et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Photolysis of model emerging contaminants in ultra-pure water: Kinetics, by-products formation and degradation pathways

(2012) F. Javier Benitez et al.   WATER RESEARCH

Childhood Hair Product Use and Earlier Age at Menarche in a Racially Diverse Study Population: A Pilot Study

(2011) Tamarra James-Todd et al.   ANNALS OF EPIDEMIOLOGY

Triclosan in individual human milk samples from Australia

(2011) Leisa-Maree L. Toms et al.   CHEMOSPHERE

Bioassay-Directed Identification of Novel Antiandrogenic Compounds in Bile of Fish Exposed to Wastewater Effluents

(2011) Pawel Rostkowski et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of bisphenol A and triclocarban on brain-specific expression of aromatase in early zebrafish embryos

(2011) E. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triclosan and Thyroid-Mediated Metamorphosis in Anurans: Differentiating Growth Effects from Thyroid-Driven Metamorphosis in Xenopus laevis

(2011) Douglas J. Fort et al.   TOXICOLOGICAL SCIENCES

Use of chemical mixtures to differentiate mechanisms of endocrine action in a small fish model

(2010) Gerald T. Ankley et al.   AQUATIC TOXICOLOGY

Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology

(2010) Natasha Thorne et al.   CHEMISTRY & BIOLOGY

Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro

(2010) Verena Christen et al.   CHEMOSPHERE

Characterization of the androgen-sensitive MDA-kb2 cell line for assessing complex environmental mixtures

(2010) Lindsey S. Blake et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Effects of Triclocarban on Intact Immature Male Rat

(2010) Antoni J. Duleba et al.   Reproductive Sciences

Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay

(2010) Jaime Freitas et al.   TOXICOLOGY IN VITRO

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Triclosan and Anuran Metamorphosis: No Effect on Thyroid-Mediated Metamorphosis in Xenopus laevis

(2009) Douglas J. Fort et al.   TOXICOLOGICAL SCIENCES

Short-term Exposure to Triclosan Decreases Thyroxine In Vivo via Upregulation of Hepatic Catabolism in Young Long-Evans Rats

(2009) Katie B. Paul et al.   TOXICOLOGICAL SCIENCES

Mixed-Model QSAR at the Glucocorticoid Receptor: Predicting the Binding Mode and Affinity of Psychotropic Drugs

(2008) Morena Spreafico et al.   ChemMedChem

In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens

(2008) Ki Chang Ahn et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Characterization of Chemical Libraries for Luciferase Inhibitory Activity

(2008) Douglas S. Auld et al.   JOURNAL OF MEDICINAL CHEMISTRY

Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan

(2008) Vikas Kumar et al.   REPRODUCTIVE TOXICOLOGY

The influence of age and gender on triclosan concentrations in Australian human blood serum

(2008) Mats Allmyr et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Triclocarban Enhances Testosterone Action: A New Type of Endocrine Disruptor?

(2007) Jiangang Chen et al.   ENDOCRINOLOGY