Article
Microbiology
Jiaqi Wang, Jiahuan Chen, Linquan Li, Huanyu Zhang, Daxin Pang, Hongsheng Ouyang, Xuemin Jim, Xiaochun Tang
Summary: Cardiac fibrosis is a fundamental process in cardiac remodeling and is associated with almost all types of cardiovascular diseases. This study explores the relationship between cardiac fibrosis and gut microbiota, finding that dysbiosis of the gut microbiota alone cannot cause cardiac fibrosis. However, healthy fecal microbiota transplantation can alleviate cardiac fibrosis. By targeting the gut microbiota and metabolites, such as probiotics, it is possible to develop new strategies for treating cardiovascular diseases.
MICROBIOLOGY SPECTRUM
(2022)
Article
Medicine, General & Internal
Anita Gasiorowska, Marek Romanowski, Ewa Walecka-Kapica, Aleksandra Kaczka, Cezary Chojnacki, Milena Padysz, Marta Siedlecka, Joanna B. Bierla, Robert E. Steinert, Bozena Cukrowska
Summary: This study aims to evaluate the effects of a product consisting of sodium butyrate, probiotics, and short-chain fructooligosaccharides on the severity of symptoms and quality of life in patients with irritable bowel syndrome (IBS). The study is a randomized double-blind placebo-controlled trial and will last for 12 weeks. The primary outcomes include changes in IBS symptoms and IBS-QOL, while the secondary outcomes include stool type, patient-recorded symptoms, adverse events, and inflammatory cytokine levels.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Nutrition & Dietetics
Sindusha Mysore Saiprasad, Olivia Grace Moreno, Dennis A. Savaiano
Summary: Supplementing with Bifidobacterium and galacto-oligosaccharides (GOS) can improve gut health and benefit lactose intolerant individuals. Most studies have reported positive effects of Bifidobacterium and GOS in managing lactose intolerance.
Article
Food Science & Technology
Jingjing Xu, Ruyue Wang, Hongtao Zhang, Jianrong Wu, Li Zhu, Xiaobei Zhan
Summary: Xanthan gum oligosaccharides, gellan gum oligosaccharides, pullulan oligosaccharides, and curdlan oligosaccharides have been identified as potential prebiotics, promoting bacterial growth and short-chain fatty acid production. Among them, xanthan gum oligosaccharides demonstrate the best prebiotic effects, enhancing the proliferation of beneficial bacteria and butyric acid-producing bacteria, leading to an increase in short-chain fatty acids level.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Masahiro Komeno, Yuki Yoshihara, Junya Kawasaki, Wataru Nabeshima, Koshi Maeda, Yuki Sasaki, Kiyotaka Fujita, Hisashi Ashida
Summary: In this study, the degradation pathways of AX and AXOs by Bifidobacterium longum subsp. longum were characterized, and the crucial roles of BlArafD and BlArafE in the assimilation of AX were identified.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Food Science & Technology
Nanami Hashikura, Ryuta Murakami, Takuma Sakurai, Ayako Horigome, Kazuya Toda, Jin-zhong Xiao, Toshitaka Odamaki
Summary: Probiotics and prebiotics have been found to have beneficial effects on host physiology through the metabolites produced by the gut microbiota. Using a pH-controlled single-batch fermenter as a model for the human gut microbiota, fecal fermentation was conducted with Bifidobacterium breve MCC1274 (probiotic), lactulose (prebiotic), or a combination of both (synbiotic) to assess their influence on the gut environment. The results showed significant differences in the composition of gut microbiota and the relative abundance of certain bacteria among the treatment groups. Metabolite analysis revealed that the synbiotic group had the highest number of detected metabolites, with some specific metabolites enriched in this group. The findings suggest that synbiotics can enhance the production of signaling molecules in the gut environment.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Aaron N. Colamarino, Thomas M. Johnson, Daniel M. Boudreaux, Joseph M. Dutner, Brian W. Stancoven, Adam R. Lincicum, Joshua A. Akers
Summary: This study evaluated the influence of probiotic bacteria supplementation, along with prebiotic inulin, on biofilm composition using an ex vivo model. The results showed that inulin supplementation increased the relative abundances of Lactobacillus and Bifidobacterium species, while decreasing the abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species. Inoculation with L. reuteri or B. animalis subsp. lactis only increased the relative abundance of the supplemented probiotic genera. Additionally, inulin supplementation led to decreased biofilm diversity.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Microbiology
Marco Calvigioni, Andrea Bertolini, Simone Codini, Diletta Mazzantini, Adelaide Panattoni, Mariacristina Massimino, Francesco Celandroni, Riccardo Zucchi, Alessandro Saba, Emilia Ghelardi
Summary: In this study, nine common probiotic strains were tested for their ability to secrete short-chain fatty acids (SCFAs) using a sensitive and specific HPLC-MS-MS method. All tested microorganisms were shown to secrete acetic acid, with only B. clausii and S. boulardii additionally able to produce propionic and butyric acids. This experimental approach contributes to the characterization of probiotics as SCFA-producing organisms and has implications for addressing SCFA deficiency.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Allergy
Sukyung Kim, Song-Yi Han, Jinyoung Lee, Na-Rae Kim, Bo Ra Lee, Hyunmi Kim, Mijeoung Kwon, Kangmo Ahn, Youngbae Noh, Sang Jong Kim, Phyrim Lee, Dongki Kim, Byung Eui Kim, Jihyun Kim
Summary: The combination therapy using Bifidobacterium longum and galactooligosaccharide (GOS) has been found to improve atopic dermatitis (AD) and increase the expression of epidermal barrier proteins.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2022)
Article
Food Science & Technology
Lei Pan, Lin Wang, Fan Zhang, Yi Zhang, Baodong Zheng
Summary: Polysaccharide fractions were extracted from Dictyophora indusiata, and their structure and bifidogenic activity were investigated. It was found that DIP0 promoted the growth of Bifidobacterium longum and its metabolic synthesis of acetic acid during fermentation.
Article
Biotechnology & Applied Microbiology
Gaoya Sun, Lingkai Jin, Guangxue Wang, Xiaoge Wang, Jin Huang
Summary: In this study, heterologous expression and homologous overexpression of ABC transporter proteins AatA and MdlB were found to improve butyric acid production in C. tyrobutyricum. The overexpression of these proteins upregulated the expression levels of key enzymes in the acetate synthesis pathway and promoted the synthesis and secretion of acetic acid. Additionally, the increase in ATPase activity facilitated sugar utilization, induced extracellular secretion of acetate, and shortened fermentation periods.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Nutrition & Dietetics
Turki S. Abujamel, Norah M. Al-Otaibi, Sameera Abuaish, Rahaf H. AlHarbi, Mushref B. Assas, Saleha Ahmad Alzahrani, Sohailah Masoud Alotaibi, Afaf El-Ansary, Kawther Aabed
Summary: This study evaluated the effect of Bifidobacterium (BF) treatment and fecal microbiota transplantation (FT) on gut microbiota in a propionic acid (PPA) rat model of autism using 16S rRNA sequencing. The results demonstrated that BF and FT treatments have the ability to regulate gut microbiota and restore dysbiosis caused by autism.
Review
Food Science & Technology
Dharmendra Kumar, Milan Kumar Lal, Som Dutt, Pinky Raigond, Sushil Sudhakar Changan, Rahul Kumar Tiwari, Kumar Nishant Chourasia, Vikas Mangal, Brajesh Singh
Summary: The current trend of health-conscious consumers and healthy food habits has led researchers to explore the development of food products with synbiotic benefits. This review article explores the alternative sources of probiotics and highlights various methods for making non-dairy synbiotics based on dietary fibers.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Article
Thermodynamics
Marco Lubrano Lavadera, Alexander A. Konnov
Summary: The laminar burning velocities of propionic acid + air flames were determined experimentally and through kinetic modeling, revealing inconsistencies in some datasets.
COMBUSTION AND FLAME
(2021)
Article
Food Science & Technology
Min Joo Kang, Huijin Jeong, Suin Kim, Jaein Shin, Youngbo Song, Byung-Hoo Lee, Hyoung-Geun Park, Tae-Ho Lee, Hai-Hua Jiang, Young-Sun Han, Bong-Gyeong Lee, Ho-Jin Lee, Min-Ju Park, Young-Seo Park
Summary: Exopolysaccharide (EPS)-producing Bifidobacterium bifidum EPS DA-LAIM was isolated from healthy human feces, and its purified EPS was analyzed for structure and evaluated for prebiotic activity. The EPS from B. bifidum EPS DA-LAIM is a glucomannan-type heteropolysaccharide with a molecular weight of 407-1007 kDa, comprising 2-mannosyl, 6-mannosyl, and 2,6-mannosyl residues. The purified EPS showed promotion in the growth of lactic acid bacteria and bifidobacterial strains, immunostimulatory activity, gastrointestinal tract tolerance, gut adhesion ability, and antioxidant activity. These findings indicate the potential of B. bifidum EPS DA-LAIM as a useful prebiotic material and probiotic candidate.
FOOD SCIENCE AND BIOTECHNOLOGY
(2023)
Article
Food Science & Technology
Lutfiye Yilmaz-Ersan, Tulay Ozcan, Arzu Akpinar-Bayizit, Murat Ali Turan, Mehmet Burak Taskin
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2017)
Article
Food Science & Technology
Tulay Ozcan, Lutfiye Yilmaz-Ersan, Arzu Akpinar-Bayizit, Berrak Delikanli
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2017)
Article
Agriculture, Dairy & Animal Science
Lutfiye Yilmaz-Ersan, Tulay Ozcan, Arzu Akpinar-Bayizit, Saliha Sahin
JOURNAL OF DAIRY SCIENCE
(2018)
Article
Food Science & Technology
Tulay Ozcan, Saliha Sahin, Arzu Akpinar-Bayizit, Lutfiye Yilmaz-Ersan
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY
(2019)
Article
Food Science & Technology
Lutfiye Yilmaz-Ersan, Murat Ali Turan
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2012)
Article
Food Science & Technology
Lutfiye Yilmaz-Ersan, Tulay Ozcan, Arzu Akpinar-Bayizit
FOOD SCIENCE AND HUMAN WELLNESS
(2020)
Article
Food Science & Technology
Esra Topcuoglu, Lutfiye Yilmaz-Ersan
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2020)
Article
Environmental Sciences
Tulay Ozcan, Lutfiye Yilmaz-Ersan, Arzu Akpinar-Bayizit, Ozge Ozcan, Berrak Delikanli-Kiyak, Merve Begum Ozyurek, Sengul Teksoy
FRESENIUS ENVIRONMENTAL BULLETIN
(2020)
Article
Agriculture, Dairy & Animal Science
Arzu Akpinar-Bayizit, Tulay Ozcan, Lutfiye Yilmaz-Ersan, Fikri Basoglu
Article
Agriculture, Dairy & Animal Science
Lutfiye Yilmaz-Ersan
Review
Agriculture, Dairy & Animal Science
Tulay Ozcan, Arzu Akpinar-Bayizit, Oya Irmak Sahin, Lutfiye Yilmaz-Ersan
Article
Microbiology
Lutfiye Yilmaz-Ersan, Arzu Akpinar-Bayizit, Tulay Ozcan, Oya Irmak Sahin, Pinar Aydinol
AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH
(2011)
Article
Environmental Sciences
Lutfiye Yilmaz-Ersan, Tulay Ozcan, Arzu Akpinar-Bayizit, Buse Usta, Mervenur Kandil, Ezgi Eroglu
FRESENIUS ENVIRONMENTAL BULLETIN
(2018)
Article
Environmental Sciences
Buse Usta, Lutfiye Yilmaz-Ersan
FRESENIUS ENVIRONMENTAL BULLETIN
(2017)