Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

(2019) Elisa Vergari et al.   Nature Communications

Glucose controls glucagon secretion by directly modulating cAMP in alpha cells

(2019) Qian Yu et al.   DIABETOLOGIA

Somatostatin is Only Partly Required for the Glucagonostatic Effect of Glucose but is Necessary for the Glucagonostatic Effect of KATPChannel Blockers

(2018) Bao-Khanh Lai et al.   DIABETES

Insulin Secretion Depends on Intra-islet Glucagon Signaling

(2018) Berit Svendsen et al.   Cell Reports

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

(2016) Alice E. Adriaenssens et al.   DIABETOLOGIA

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

(2016) Michael R. DiGruccio et al.   Molecular Metabolism

Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counterregulation in Biobreeding Diabetic Rats

(2013) Negar Karimian et al.   DIABETES

Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats

(2013) J. T. Y. Yue et al.   DIABETES

Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

(2012) J Pedersen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin

(2012) A. C. Hauge-Evans et al.   DIABETOLOGIA

Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats

(2011) J. T. Y. Yue et al.   DIABETES

The role of dysregulated glucagon secretion in type 2 diabetes

(2011) D. D'Alessio   DIABETES OBESITY & METABOLISM

Paracrinology of islets and the paracrinopathy of diabetes

(2010) R. H. Unger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel high-affinity peptide antagonist to the insulin receptor

(2008) Lauge Schäffer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Somatostatin Secreted by Islet  -Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

(2008) A. C. Hauge-Evans et al.   DIABETES

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

(2008) J. de Heer et al.   DIABETOLOGIA