4.5 Article

Plasticity in olfactory bulb circuits

Journal

CURRENT OPINION IN NEUROBIOLOGY
Volume 64, Issue -, Pages 17-23

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2020.01.007

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Funding

  1. N.I.H. [R01 DC014690, R01 NS091010A, R01 EY025349, P30EY022589]
  2. David and Lucile Packard Foundation
  3. NSF [1734940]
  4. Div Of Electrical, Commun & Cyber Sys
  5. Directorate For Engineering [1734940] Funding Source: National Science Foundation

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Olfaction is crucial for animal survival and human well-being. The olfactory bulb is the obligatory input station for olfactory information. In contrast to the traditional view as a static relay station, recent evidence indicates that the olfactory bulb dynamically processes olfactory information in an experience-dependent and context-dependent manner. Here, we review recent studies on experience-dependent plasticity of the main circuit components within the olfactory bulb of rodents. We argue that the olfactory bulb plasticity allows optimal representations of behaviorally-relevant odors in the continuously changing olfactory environment.

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