Article
Geriatrics & Gerontology
Daniela Renftle, Sara Becker, Kathrin Brockmann, Thomas Gasser, Katja Michaelis, Susanne Solbrig, Patricia Sulzer, Andreas Johnen, Inga Liepelt-Scarfone
Summary: This study evaluated the psychometric properties and validity of the Dementia Apraxia Test (DATE) in patients with Parkinson's disease. The results showed that DATE scores were associated with cognition and daily living function, but were confounded by motor impairment and age.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
(2022)
Article
Neurosciences
Jung E. Park, Mark Hallett, Hyung-Ryeol Jang, Lee-Uhn Kim, Keun-Jin Park, Seo-Kyung Kim, Jeong-Eun Bae, Ji-yi Hong, Jeong-Ho Park
Summary: Anodal transcranial direct current stimulation of the left posterior parietal cortex followed by motor practice appears to be effective in improving limb-kinetic apraxia in patients with Parkinson's disease, with immediate and sustained effects.
EXPERIMENTAL BRAIN RESEARCH
(2022)
Article
Clinical Neurology
Claudia C. Schmidt, Elisabeth I. S. Achilles, Katharina Bolte, Nina N. Kleineberg, Monika K. Richter, Natalie Schloss, Gereon R. Fink, Peter H. Weiss
Summary: The study investigated the association between subcortical gray matter lesions and apraxic deficits in LH stroke patients, finding that lesions in the caudate nucleus were significantly related to apraxic deficits, while lesions in the globus pallidus were associated with a lower likelihood of apraxia. Other subcortical structures did not show significant differences in lesion load between apraxic and nonapraxic patients.
Article
Behavioral Sciences
D. Romano, G. Tosi, V. Gobbetto, P. Pizzagalli, R. Avesani, V. Moro, A. Maravita
Summary: The study found that MB training improved apraxia compared to imitation and rest conditions, and this improvement was correlated with the impact of the mirror box on body representation. MB training shows promising effects in promoting recovery from apraxia.
Article
Clinical Neurology
Sungyang Jo, Jungsu S. Oh, E-Nae Cheong, Hyung Ji Kim, Sunju Lee, Minyoung Oh, Jae Seung Kim, Sun Ju Chung, Chong S. Lee, Miseon Kwon, Dongwha Kang, Jae-Hong Lee
Summary: This study used FDG-PET to reveal distinct glucose hypometabolism patterns in ideomotor and imitation apraxia subtypes in CBS patients. Patients with both ideomotor and imitation apraxia were more likely to exhibit the typical features of CBS and progressive supranuclear palsy compared to those with only one type of apraxia. These findings contribute to our understanding of the brain networks underlying apraxia in relation to the clinical features of CBS.
PARKINSONISM & RELATED DISORDERS
(2021)
Article
Medicine, General & Internal
Wookyung Park, Jongwook Kim, MinYoung Kim
Summary: This case report suggests the possible therapeutic efficacy of immersive virtual reality (VR) training for ideomotor apraxia in stroke patients, with significant improvement in symptoms observed within 3 months.
Article
Clinical Neurology
Christen M. O'Neal, Syed A. Ahsan, Nicholas B. Dadario, R. Dineth Fonseka, Isabella M. Young, Allan Parker, B. David Maxwell, Jacky T. Yeung, Robert G. Briggs, Charles Teo, Michael E. Sughrue
Summary: This study aimed to propose an anatomically concise network model for the neurophysiologic basis of IMA, utilizing intrinsic white matter connectivity. By utilizing meta-analytic software and deterministic tractography on healthy participants, six ROIs were identified as constituting the IMA network, primarily involving fronto-parietal connections and U-shaped association fibers. These findings support previous models of dual-stream motor processing and suggest the need for further clarification through voxel-based lesion studies.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Article
Medicine, General & Internal
Sung Ho Jang, Dong Hyun Byun
Summary: This paper reports on a case of delayed gait recovery in a chronic hemiparetic stroke patient due to resolution of limb-kinetic apraxia (LKA). The patient showed significant improvement in gait after receiving adequate doses of dopaminergic drugs to resolve the LKA. These results highlight the importance of identifying the neurological potential for gait ability and the underlying causes of gait inability in stroke patients.
Article
Neurosciences
Ewere Marie Ogbimi, Fatai Momodu Akemokwe, Olubunmi Ogunrin
Summary: This study aimed to determine the frequency, pattern, and predictors of cognitive impairments in patients with Parkinson's disease in Nigeria. The results showed that the frequency of cognitive impairment in Parkinson's disease patients was 50%, compared to 3.3% in the control group. The study also identified several factors, including recall deficiency, poor naming ability, and apraxia, as predictors of cognitive impairment in Parkinson's disease.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Neuroimaging
Jae Woo Chung, Abigail E. Bower, Ibrahim Malik, Justin P. Martello, Christopher A. Knight, John J. Jeka, Roxana G. Burciu
Summary: This study investigated the neural correlates of lower limb movements in individuals with and without Parkinson's disease (PD), and found extensive brain changes in PD related to lower limb symptoms, suggesting the involvement of both cortico-basal ganglia and cortico-cerebellar motor circuits in lower limb symptoms in PD.
NEUROIMAGE-CLINICAL
(2023)
Article
Neurosciences
Jae Woo Chung, Abigail E. Bower, Ibrahim Malik, Justin P. Martello, Christopher A. Knight, John J. Jeka, Roxana G. Burciu
Summary: This study examined the differences in brain activity during a task that involved the coordination of non-homologous limbs in individuals with and without Parkinson's disease (PD) using functional magnetic resonance imaging (fMRI).
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Elisabeth Rounis, Ferdinand Binkofski
Summary: Stroke is a major cause of disability worldwide, and limb apraxia is a group of motor disorders associated with greater disability and dependence after stroke. In this review, a hierarchical organization of limb apraxia is proposed, distinguishing several visuomotor pathways that lead to purposeful actions. Further studies are needed to stratify patients using modern neurophysiology and neuroimaging techniques to provide targeted and personalized therapies for these disorders in the future.
Article
Health Care Sciences & Services
Laura Sanchez-Bermejo, Pedro Jesus Milla-Ortega, Jose Manuel Perez-Marmol
Summary: This study examined the relationship between upper limb apraxia (ULA) and self-efficacy in post-stroke patients. The findings revealed that imitative movements and daily life performance associated with ULA are related to general self-efficacy and self-efficacy for managing symptoms among these patients.
Article
Multidisciplinary Sciences
Gloria Vergara-Diaz, Jean-Francois Daneault, Federico Parisi, Chen Admati, Christina Alfonso, Matilde Bertoli, Edoardo Bonizzoni, Gabriela Ferreira Carvalho, Gianluca Costante, Eric Eduardo Fabara, Naama Fixler, Fatemah Noushin Golabchi, John Growdon, Stefano Sapienza, Phil Snyder, Shahar Shpigelman, Lewis Sudarsky, Margaret Daeschler, Lauren Bataille, Solveig K. Sieberts, Larsson Omberg, Steven Moore, Paolo Bonato
Summary: The study aimed to evaluate if wearable sensor data can be used to accurately estimate limb-specific symptom severity in Parkinson's disease patients. Nineteen PD patients performed motor tasks during laboratory visits and used a smartphone app for periodic tasks at home.
Article
Neurosciences
Naomi P. Visanji, Mahdi Ghani, Eric Yu, Erfan Ghani Kakhki, Christine Sato, Danielle Moreno, Taline Naranian, Yu-Yan Poon, Maryam Abdollahi, Maryam Naghibzadeh, Rajasumi Rajalingam, Andres M. Lozano, Suneil K. Kalia, Mojgan Hodaie, Melanie Cohn, Marta Statucka, Alexandre Boutet, Gavin J. B. Elias, Jurgen Germann, Renato Munhoz, Anthony E. Lang, Ziv Gan-Or, Ekaterina Rogaeva, Alfonso Fasano
Summary: The study aimed to identify genetic variants associated with clinical heterogeneity in DBS outcome of PD patients, with the potential to improve patient selection for DBS surgery. The findings suggest a genetic underpinning to the response to surgical intervention, particularly with respect to axial motor improvement.
JOURNAL OF PARKINSONS DISEASE
(2022)
Article
Behavioral Sciences
Andrea Gajardo-Vidal, Maxime Montembeault, Diego L. Lorca-Puls, Abigail E. Licata, Rian Bogley, Sabrina Erlhoff, Buddhika Ratnasiri, Zoe Ezzes, Giovanni Battistella, Elena Tsoy, Christa Watson Pereira, Jessica Deleon, Boon Lead Tee, Maya L. Henry, Zachary A. Miller, Katherine P. Rankin, Maria Luisa Mandelli, Katherine L. Possin, Maria Luisa Gorno-Tempini
Summary: This study investigates the potential differences in processing speed and neural correlates among the three variants of Primary Progressive Aphasia (PPA). The findings reveal that non-verbal cognitive abilities, such as processing speed, are significantly impacted in nfvPPA and lvPPA patients compared to healthy controls and svPPA patients. Neuroimaging results confirm the importance of fronto-parietal regions associated with processing speed and executive control.
Article
Behavioral Sciences
Holger Wiese, Tsvetomila Popova, Maya Schipper, Deni Zakriev, Mike Burton, Andrew W. Young
Summary: Previous experiments have shown that brief exposure to unfamiliar individuals leads to the formation of new facial representations, which undergo changes and consolidation within the first day after learning.
Article
Behavioral Sciences
Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Paul Wendiggensen, Veit Roessner, Bernhard Hommel, Christian Beste
Summary: Individuals organize events in their environment by partitioning them into discrete units. This study reveals that the neural activity in the brain plays a critical role in this process, reflecting the key elements of event segmentation.
Article
Behavioral Sciences
Zhenzhen Huo, Zhiyi Chen, Rong Zhang, Junye Xu, Tingyong Feng
Summary: Procrastination has adverse effects on personal growth and social development. Reward sensitivity is positively correlated with procrastination. This study used VBM and RSFC analyses to investigate the neural substrates underlying the association between reward sensitivity and procrastination. The results showed that the functional connectivity of the right parahippocampal gyrus-precuneus mediated the relationship between reward sensitivity and procrastination.
Article
Behavioral Sciences
Stefano Lasaponara, Gabriele Scozia, Silvana Lozito, Mario Pinto, David Conversi, Marco Costanzi, Tim Vriens, Massimo Silvetti, Fabrizio Doricchi
Summary: Cholinergic (Ach), Noradrenergic (NE), and Dopaminergic (DA) pathways are crucial in regulating spatial attention and determining inter-individual differences in temperamental traits. This study found that temperamental traits predict individual differences in the ability to orient spatial attention based on the probabilistic association between cues and targets. These findings highlight the importance of considering temperamental and personality traits in social and professional environments where attention control is essential.
Article
Behavioral Sciences
Darren J. Yeo, Courtney Pollack, Benjamin N. Conrad, Gavin R. Price
Summary: The processing of numerals as visual objects is supported by an Inferior Temporal Numeral Area (ITNA) in the bilateral inferior temporal gyri (ITG). Extant findings suggest some degree of hemispheric asymmetry in how the bilateral ITNAs process numerals. The study found that digit sensitivity did not differ between ITNAs, and digit sensitivity in both left and right ITNAs was associated with calculation skills. The study also revealed a right lateralization in engagement in alphanumeric categorization, and that the right ITNA showed greater discriminability between digits and letters.
Review
Behavioral Sciences
Beste Gulsuna, Abuzer Gungor, Alp O. Borcer, Ugur Ture
Summary: The fiber dissection technique has been used to study the internal structures of the brain, with less focus on white matter. The sagittal stratum, a white matter structure, has not received enough attention and has been a subject of controversy. Recent studies suggest potential functions of the sagittal stratum, emphasizing the importance of understanding this structure accurately.
Article
Behavioral Sciences
Nora Geiser, Brigitte Charlotte Kaufmann, Samuel Elia Johannes Knobel, Dario Cazzoli, Tobias Nef, Thomas Nyffeler
Summary: This study compared the effects of auditory and visual motion stimulation on spatial neglect and found that both interventions were equally effective in improving neglect. Multimodal motion stimulation also improved neglect, but did not show greater improvement than unimodal auditory or visual motion stimulation alone.
Article
Behavioral Sciences
Anna E. Hughes, Anna Nowakowska, Alasdair D. F. Clarke
Summary: This study examines the relationship between search slopes and search efficiency in visual search tasks, introduces the Target Contrast Signal (TCS) Theory, and extends it to a Bayesian multi-level framework. The findings demonstrate that TCS can predict data well, but distinguishing between contrast combination models proves to be difficult.