Nintedanib and a bi-specific anti-VEGF/Ang2 nanobody selectively prevent brain metastases of lung adenocarcinoma cells

Brain Metastasis Cell Lines Panel: a public resource of organotropic cell lines

(2020) Manuel Valiente et al.   CANCER RESEARCH

Nonspecific immunoglobulin G is effective in preventing and treating cancer in mice

(2019) Qian Xu et al.   Cancer Management and Research

Bevacizumab Reduces S100A9-Positive MDSCs Linked to Intracranial Control in Patients with EG FR -Mutant Lung Adenocarcinoma

(2018) Po-Hao Feng et al.   Journal of Thoracic Oncology

Preservation of cognitive function following whole brain radiotherapy in patients with brain metastases: Complications, treatments, and the emerging role of memantine

(2018) Meghan Lynch   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

A framework for the development of effective anti-metastatic agents

(2018) Robin L. Anderson et al.   Nature Reviews Clinical Oncology

Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

(2017) Solange Peters et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of VEGF and Angiopoietin-2 to Reduce Brain Metastases of Breast Cancer Burden

(2017) Kaci A. Bohn et al.   Frontiers in Pharmacology

Temporal and spatial discordance of programmed cell death-ligand 1 expression and lymphocyte tumor infiltration between paired primary lesions and brain metastases in lung cancer

(2016) A. S. Mansfield et al.   ANNALS OF ONCOLOGY

Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial

(2016) Sarah B Goldberg et al.   LANCET ONCOLOGY

Nintedanib plus pemetrexed versus placebo plus pemetrexed in patients with relapsed or refractory, advanced non-small cell lung cancer (LUME-Lung 2): A randomized, double-blind, phase III trial

(2016) Nasser H. Hanna et al.   LUNG CANCER

Bevacizumab Prevents Brain Metastases Formation in Lung Adenocarcinoma

(2016) A. Ilhan-Mutlu et al.   MOLECULAR CANCER THERAPEUTICS

Bevacizumab Preconditioning Followed by Etoposide and Cisplatin Is Highly Effective in Treating Brain Metastases of Breast Cancer Progressing from Whole-Brain Radiotherapy

(2015) Y.-S. Lu et al.   CLINICAL CANCER RESEARCH

Bevacizumab in Patients with Nonsquamous Non-Small Cell Lung Cancer and Asymptomatic, Untreated Brain Metastases (BRAIN): A Nonrandomized, Phase II Study

(2015) B. Besse et al.   CLINICAL CANCER RESEARCH

Unsanctifying the sanctuary: challenges and opportunities with brain metastases

(2015) S. Puhalla et al.   NEURO-ONCOLOGY

Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases

(2015) Anna S. Berghoff et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Alleviation of Brain Edema and Restoration of Functional Independence by Bevacizumab in Brain-Metastatic Breast Cancer: A Case Report

(2014) Anna S. Berghoff et al.   Breast Care

Intravenous Immunoglobulin Promotes Antitumor Responses by Modulating Macrophage Polarization

(2014) Angeles Domínguez-Soto et al.   JOURNAL OF IMMUNOLOGY

Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small-cell lung cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial

(2014) Martin Reck et al.   LANCET ONCOLOGY

CNS metastases in breast cancer patients: prognostic implications of tumor subtype

(2014) C. Bachmann et al.   MEDICAL ONCOLOGY

Prognostic significance of Ki67 proliferation index, HIF1 alpha index and microvascular density in patients with non-small cell lung cancer brain metastases

(2014) A. S. Berghoff et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Henoch–Schönlein purpura (HSP) and high-dose immunoglobulin treatment in patient with familiar prostatic adenocarcinoma

(2013) Małgorzata Sobieszczańska et al.   Human Vaccines & Immunotherapeutics

Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial

(2012) Kim Margolin et al.   LANCET ONCOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Epidemiology of Brain Metastases

(2011) Lakshmi Nayak et al.   Current Oncology Reports

Primary Analysis of a Phase II Randomized Trial Radiation Therapy Oncology Group (RTOG) 0212: Impact of Different Total Doses and Schedules of Prophylactic Cranial Irradiation on Chronic Neurotoxicity and Quality of Life for Patients With Limited-Disease Small-Cell Lung Cancer

(2010) Aaron H. Wolfson et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients With Locally Advanced Non–Small-Cell Lung Cancer: Primary Analysis of Radiation Therapy Oncology Group Study RTOG 0214

(2010) Elizabeth M. Gore et al.   JOURNAL OF CLINICAL ONCOLOGY

Efficacy and safety of bevacizumab in active brain metastases from non-small cell lung cancer

(2010) Kevin C. De Braganca et al.   JOURNAL OF NEURO-ONCOLOGY

Anti-vascular endothelial growth factor (VEGF) specific activity of intravenous immunoglobulin (IVIg)

(2009) M. Damianovich et al.   INTERNATIONAL IMMUNOLOGY

Phase III Trial of Cisplatin Plus Gemcitabine With Either Placebo or Bevacizumab As First-Line Therapy for Nonsquamous Non–Small-Cell Lung Cancer: AVAiL

(2009) Martin Reck et al.   JOURNAL OF CLINICAL ONCOLOGY

Real-time imaging reveals the single steps of brain metastasis formation

(2009) Yvonne Kienast et al.   NATURE MEDICINE

BIBF 1120: Triple Angiokinase Inhibitor with Sustained Receptor Blockade and Good Antitumor Efficacy

(2008) F. Hilberg et al.   CANCER RESEARCH

Improvement in Visual Fields in a Patient With Melanoma-Associated Retinopathy Treated With Intravenous Immunoglobulin

(2008) Chereddy Subhadra et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Metastasis: a therapeutic target for cancer

(2008) Patricia S Steeg et al.   Nature clinical practice. Oncology