Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity

Published 2020 View Full Article

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Title
Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity
Authors
Keywords
long QT syndrome, induced pluripotent stem cells, drug development, high-throughput screening, medicinal chemistry, mexiletine, arrhythmia, cardiomyocyte, electrophysiology, disease modeling
Journal
Cell Stem Cell
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2020-09-14
DOI
10.1016/j.stem.2020.08.003

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