Loss of PTEN expression is associated with PI3K pathway-dependent metabolic reprogramming in hepatocellular carcinoma

Artemisiae Iwayomogii Herba Inhibits Growth, Motility, and the PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma Cells

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Genetic alterations and expression of PTEN and its relationship with cancer stem cell markers to investigate pathogenesis and to evaluate prognosis in hepatocellular carcinoma

(2019) Dingbao Chen et al.   JOURNAL OF CLINICAL PATHOLOGY

Hepatocellular Carcinoma

(2019) Augusto Villanueva   NEW ENGLAND JOURNAL OF MEDICINE

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The Warburg Effect, Lactate, and Nearly a Century of Trying to Cure Cancer

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The Clinical Spectrum of PTEN Mutations

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The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition

(2019) Qiqi Li et al.   Cell Reports

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MiR-494-3p promotes PI3K/AKT pathway hyperactivation and human hepatocellular carcinoma progression by targeting PTEN

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STAT3-induced upregulation of lncRNA CASC11 promotes the cell migration, invasion and epithelial-mesenchymal transition in hepatocellular carcinoma by epigenetically silencing PTEN and activating PI3K/AKT signaling pathway

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(2018) Laura Kulik et al.   GASTROENTEROLOGY

Lipid Metabolic Reprogramming in Hepatocellular Carcinoma

(2018) Hayato Nakagawa et al.   Cancers

Long Noncoding RNA lncARSR Promotes Doxorubicin Resistance in Hepatocellular Carcinoma via Modulating PTEN-PI3K/Akt Pathway

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PTEN: A potential prognostic marker in virus-induced hepatocellular carcinoma

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The Warburg Effect: How Does it Benefit Cancer Cells?

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Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects

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Tumor suppressor p53 and its mutants in cancer metabolism

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Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice

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Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1α signaling pathway

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Increased Concentrations of Fructose 2,6-Bisphosphate Contribute to the Warburg Effect in Phosphatase and Tensin Homolog (PTEN)-deficient Cells

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Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Signaling Regulates Mitochondrial Biogenesis and Respiration via Estrogen-related Receptor α (ERRα)

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The metabolomic window into hepatobiliary disease

(2013) Diren Beyoğlu et al.   JOURNAL OF HEPATOLOGY

Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State

(2012) Isabel Garcia-Cao et al.   CELL

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

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