Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum

Published 2020 View Full Article

Authors

Keywords

malaria parasite, Plasmodium falciparum, antimalarial, structure-facilitated drug discovery, glucose transporter, hexose transporter, PfHT1, crystal structure, inhibitor-binding-induced pocket, orthosteric and allosteric dual inhibition

Journal

CELL

Volume 183, Issue 1, Pages 258-268.e12

Publisher

Elsevier BV

Online

2020-08-28

DOI

10.1016/j.cell.2020.08.015

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