Older adult participation in cancer clinical trials: A systematic review of barriers and interventions
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Older adult participation in cancer clinical trials: A systematic review of barriers and interventions
Authors
Keywords
-
Journal
CA-A CANCER JOURNAL FOR CLINICIANS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-10-02
DOI
10.3322/caac.21638
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A geriatric assessment (GA) intervention to reduce treatment toxicity in older patients with advanced cancer: A University of Rochester Cancer Center NCI community oncology research program cluster randomized clinical trial (CRCT).
- (2020) Supriya Gupta Mohile et al. JOURNAL OF CLINICAL ONCOLOGY
- Development of a telehealth geriatric assessment model in response to the COVID-19 pandemic
- (2020) Grace DiGiovanni et al. Journal of Geriatric Oncology
- AGS Report on Engagement Related to the NIH Inclusion Across the Lifespan Policy
- (2019) Camille P. Vaughan et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Generating Real-World Tumor Burden Endpoints from Electronic Health Record Data: Comparison of RECIST, Radiology-Anchored, and Clinician-Anchored Approaches for Abstracting Real-World Progression in Non-Small Cell Lung Cancer
- (2019) Sandra D. Griffith et al. ADVANCES IN THERAPY
- Optimizing chemotherapy for frail and elderly patients (pts) with advanced gastroesophageal cancer (aGOAC): The GO2 phase III trial.
- (2019) Peter S Hall et al. JOURNAL OF CLINICAL ONCOLOGY
- Barriers to clinical trial enrollment of older adults with cancer: A qualitative study of the perceptions of community and academic oncologists
- (2019) Mina S. Sedrak et al. Journal of Geriatric Oncology
- Development of a strategic plan for the dissemination and communication of aging research through the Cancer and Aging Research Group (CARG) infrastructure grant
- (2019) Ishwaria M. Subbiah et al. Journal of Geriatric Oncology
- Geriatric oncology health services research: Cancer and Aging Research Group Infrastructure Core
- (2019) Melisa L. Wong et al. Journal of Geriatric Oncology
- Cores for geriatric oncology infrastructure in the cancer and aging research group: Biostatistics, epidemiology, and research design (the analytics core)
- (2019) Mina S. Sedrak et al. Journal of Geriatric Oncology
- Factors Associated With Age Disparities Among Cancer Clinical Trial Participants
- (2019) Ethan B. Ludmir et al. JAMA Oncology
- Behavioral, psychological, and supportive care interventions in geriatric oncology: The cancer and aging group infrastructure core
- (2019) Rawad Elias et al. Journal of Geriatric Oncology
- Developing a clinical and biological measures of aging core: Cancer and aging research group infrastructure
- (2019) Thuy T. Koll et al. Journal of Geriatric Oncology
- Developing sustainable national infrastructure supporting high-impact research to improve the care of older adults with cancer: A Delphi investigation of geriatric oncology experts
- (2019) Maya Anand et al. Journal of Geriatric Oncology
- Decreasing incidence of upper age restriction enrollment criteria among cancer clinical trials
- (2019) Ethan B. Ludmir et al. Journal of Geriatric Oncology
- Symptom burden among older breast cancer survivors: The Thinking and Living With Cancer (TLC) study
- (2019) Jeanne S. Mandelblatt et al. CANCER
- Evolution of Cancer Care Delivery Research in the NCI Community Oncology Research Program
- (2019) Ann M Geiger et al. JNCI-Journal of the National Cancer Institute
- The Women's Health Initiative (WHI) Life and Longevity After Cancer (LILAC) Study: Description and Baseline Characteristics of Participants
- (2018) Electra D. Paskett et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Using oncology real-world evidence for quality improvement and discovery: the case for ASCO's CancerLinQ
- (2018) Robert S Miller et al. Future Oncology
- Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology
- (2018) Supriya G. Mohile et al. JOURNAL OF CLINICAL ONCOLOGY
- Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer
- (2018) Enrique Soto-Perez-de-Celis et al. LANCET ONCOLOGY
- Promoting Accrual of Older Patients with Cancer to Clinical Trials: An Alliance for Clinical Trials in Oncology Member Survey (A171602)
- (2018) Rachel A. Freedman et al. ONCOLOGIST
- Challenges of conducting a prospective clinical trial for older patients: Lessons learned from NCCTG N0949 (alliance)
- (2018) Nadine J. McCleary et al. Journal of Geriatric Oncology
- What Every Oncologist Should Know About Geriatric Assessment for Older Patients With Cancer: Young International Society of Geriatric Oncology Position Paper
- (2018) Kah Poh Loh et al. Journal of Oncology Practice
- Participation of elderly gynecological cancer patients in clinical trials
- (2018) Katharina Prieske et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- OUP accepted manuscript
- (2018) JNCI-Journal of the National Cancer Institute
- Community Oncologists' Decision-Making for Treatment of Older Patients With Cancer
- (2018) Supriya G. Mohile et al. Journal of the National Comprehensive Cancer Network
- A Phase II Trial of Older Adults With Metastatic Breast Cancer Receiving nab-Paclitaxel: Melding the Fields of Geriatrics and Oncology
- (2018) Arti Hurria et al. Clinical Breast Cancer
- Inclusion Across the Lifespan
- (2018) Marie A. Bernard et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL
- (2018) Jennifer A. Woyach et al. NEW ENGLAND JOURNAL OF MEDICINE
- Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement
- (2017) Edward S. Kim et al. JOURNAL OF CLINICAL ONCOLOGY
- Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology–Friends of Cancer Research Organ Dysfunction, Prior or Concurrent Malignancy, and Comorbidities Working Group
- (2017) Stuart M. Lichtman et al. JOURNAL OF CLINICAL ONCOLOGY
- Enrollment of older adults on oncology trials: An FDA perspective
- (2017) Harpreet Singh et al. Journal of Geriatric Oncology
- Research Priorities in Geriatric Oncology: Addressing the Needs of an Aging Population
- (2017) Arti Hurria et al. Journal of the National Comprehensive Cancer Network
- Senior Adult Oncology, Version 2.2014
- (2017) Arti Hurria et al. Journal of the National Comprehensive Cancer Network
- Participation of the Elderly Population in Clinical Trials: Barriers and Solutions
- (2017) Aaron C. Denson et al. Cancer Control
- The association of financial difficulties with clinical outcomes in cancer patients: secondary analysis of 16 academic prospective clinical trials conducted in Italy
- (2016) F. Perrone et al. ANNALS OF ONCOLOGY
- Improving the quality of survivorship for older adults with cancer
- (2016) Supriya G. Mohile et al. CANCER
- Validation of a Prediction Tool for Chemotherapy Toxicity in Older Adults With Cancer
- (2016) Arti Hurria et al. JOURNAL OF CLINICAL ONCOLOGY
- Use of a Comprehensive Geriatric Assessment for the Management of Elderly Patients With Advanced Non–Small-Cell Lung Cancer: The Phase III Randomized ESOGIA-GFPC-GECP 08-02 Study
- (2016) Romain Corre et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical trial accrual in older cancer patients: The most important steps are the first ones
- (2016) Gretchen Kimmick Journal of Geriatric Oncology
- Comparing attitudes of younger and older patients towards cancer clinical trials
- (2016) Olubukola Ayodele et al. Journal of Geriatric Oncology
- Educational initiatives in geriatric oncology – Who, why, and how?
- (2016) Tina Hsu Journal of Geriatric Oncology
- Geriatric assessment with management in cancer care: Current evidence and potential mechanisms for future research
- (2016) Allison Magnuson et al. Journal of Geriatric Oncology
- Treatment-related toxicities in older adults with head and neck cancer: A population-based analysis
- (2015) Caitriona B. O'Neill et al. CANCER
- Improving the Evidence Base for Treating Older Adults With Cancer: American Society of Clinical Oncology Statement
- (2015) Arti Hurria et al. JOURNAL OF CLINICAL ONCOLOGY
- Validity and Reliability of the US National Cancer Institute’s Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)
- (2015) Amylou C. Dueck et al. JAMA Oncology
- NCI launches program for community-based clinical research: NCORP replaces 2 previous programs
- (2014) Carrie Printz CANCER
- Designing Therapeutic Clinical Trials for Older and Frail Adults With Cancer: U13 Conference Recommendations
- (2014) Arti Hurria et al. JOURNAL OF CLINICAL ONCOLOGY
- International Society of Geriatric Oncology Consensus on Geriatric Assessment in Older Patients With Cancer
- (2014) Hans Wildiers et al. JOURNAL OF CLINICAL ONCOLOGY
- Slow accrual of elderly patients with metastatic breast cancer in the Dutch multicentre OMEGA study
- (2013) M.E. Hamaker et al. BREAST
- Barriers to inclusion of older adults in randomised controlled clinical trials on Non-Hodgkin’s lymphoma: A systematic review
- (2013) Carine Bellera et al. CANCER TREATMENT REVIEWS
- Lumpectomy Plus Tamoxifen With or Without Irradiation in Women Age 70 Years or Older With Early Breast Cancer: Long-Term Follow-Up of CALGB 9343
- (2013) Kevin S. Hughes et al. JOURNAL OF CLINICAL ONCOLOGY
- End Points and Trial Design in Geriatric Oncology Research: A Joint European Organisation for Research and Treatment of Cancer–Alliance for Clinical Trials in Oncology–International Society of Geriatric Oncology Position Article
- (2013) Hans Wildiers et al. JOURNAL OF CLINICAL ONCOLOGY
- Variability in the Treatment of Elderly Patients with Stage IIIA (N2) Non–Small-Cell Lung Cancer
- (2013) Mark F. Berry et al. Journal of Thoracic Oncology
- Heterogeneity in Healthy Aging
- (2013) D. J. Lowsky et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Overall treatment utility: A novel outcome measure to convey the balance of benefits and harms from cancer treatment
- (2013) C. Handforth et al. Journal of Geriatric Oncology
- Adjuvant chemotherapy and differential invasive breast cancer specific survival in elderly women
- (2013) Henry G. Kaplan et al. Journal of Geriatric Oncology
- The National Cancer Institute–American Society of Clinical Oncology Cancer Trial Accrual Symposium: Summary and Recommendations
- (2013) Andrea M. Denicoff et al. Journal of Oncology Practice
- Barriers to therapeutic clinical trials enrollment: Differences between African-American and white cancer patients identified at the time of eligibility assessment
- (2012) Lynne Penberthy et al. Clinical Trials
- Patient and Physician Decision Styles and Breast Cancer Chemotherapy Use in Older Women: Cancer and Leukemia Group B Protocol 369901
- (2012) Jeanne S. Mandelblatt et al. JOURNAL OF CLINICAL ONCOLOGY
- Under-Representation of Older Adults in Cancer Registration Trials: Known Problem, Little Progress
- (2012) Kevin S. Scher et al. JOURNAL OF CLINICAL ONCOLOGY
- A Prospective Analysis of the Influence of Older Age on Physician and Patient Decision-Making When Considering Enrollment in Breast Cancer Clinical Trials (SWOG S0316)
- (2012) S. H. Javid et al. ONCOLOGIST
- Predicting the risk of chemotherapy toxicity in older patients: The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score
- (2011) Martine Extermann et al. CANCER
- Predicting Chemotherapy Toxicity in Older Adults With Cancer: A Prospective Multicenter Study
- (2011) Arti Hurria et al. JOURNAL OF CLINICAL ONCOLOGY
- Comorbidities Alone Do Not Explain the Undertreatment of Colorectal Cancer in Older Adults: A French Population-Based Study
- (2011) Valérie Quipourt et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial
- (2011) Matthew T Seymour et al. LANCET
- Breast Cancer Adjuvant Chemotherapy Decisions in Older Women: The Role of Patient Preference and Interactions With Physicians
- (2010) Jeanne S. Mandelblatt et al. JOURNAL OF CLINICAL ONCOLOGY
- Geriatric oncology research in the cooperative groups: A report of a SIOG special meeting
- (2010) Arti Hurria et al. Journal of Geriatric Oncology
- Clinical trial recruitment challenges with older adults with cancer
- (2009) Judith K. Payne et al. APPLIED NURSING RESEARCH
- Participation of older newly-diagnosed cancer patients in an observational prospective pilot study: an example of recruitment and retention
- (2009) Martine TE Puts et al. BMC CANCER
- Adjuvant Chemotherapy in Older Women with Early-Stage Breast Cancer
- (2009) Hyman B. Muss et al. NEW ENGLAND JOURNAL OF MEDICINE
- Difficulties in recruiting older people in clinical trials: An examination of barriers and solutions
- (2009) I. Ridda et al. VACCINE
- Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
- (2009) David Moher et al. PLOS MEDICINE
- Role of Age and Health in Treatment Recommendations for Older Adults With Breast Cancer: The Perspective of Oncologists and Primary Care Providers
- (2008) Arti Hurria et al. JOURNAL OF CLINICAL ONCOLOGY
- Barriers to Enrollment of Elderly Adults in Early-Phase Cancer Clinical Trials
- (2008) Michele Basche et al. Journal of Oncology Practice
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started