Article
Genetics & Heredity
Elodie Fiot, Bertille Alauze, Bruno Donadille, Dinane Samara-Boustani, Muriel Houang, Gianpaolo De Filippo, Anne Bachelot, Clemence Delcour, Constance Beyler, Emilie Bois, Emmanuelle Bourrat, Emmanuel Bui Quoc, Nathalie Bourcigaux, Catherine Chaussain, Ariel Cohen, Martine Cohen-Solal, Sabrina Da Costa, Claire Dossier, Stephane Ederhy, Monique Elmaleh, Laurence Iserin, Helene Lengline, Armelle Poujol-Robert, Dominique Roulot, Jerome Viala, Frederique Albarel, Elise Bismuth, Valerie Bernard, Claire Bouvattier, Aude Brac, Patricia Bretones, Nathalie Chabbert-Buffet, Philippe Chanson, Regis Coutant, Marguerite de Warren, Beatrice Demaret, Lise Duranteau, Florence Eustache, Lydie Gautheret, Georges Gelwane, Claire Gourbesville, Mickael Grynberg, Karinne Gueniche, Carina Jorgensen, Veronique Kerlan, Charlotte Lebrun, Christine Lefevre, Francoise Lorenzini, Sylvie Manouvrier, Catherine Pienkowski, Rachel Reynaud, Yves Reznik, Jean-Pierre Siffroi, Anne-Claude Tabet, Maithe Tauber, Vanessa Vautier, Igor Tauveron, Sebastien Wambre, Delphine Zenaty, Irene Netchine, Michel Polak, Philippe Touraine, Jean-Claude Carel, Sophie Christin-Maitre, Juliane Leger
Summary: Turner syndrome is a rare condition characterized by the absence of all or part of one X chromosome in some or all cells. It affects female growth and gonadal development and is associated with an increased risk of various congenital and acquired diseases. The French National Diagnosis and Care Protocol aims to provide optimal management and care for patients with Turner syndrome.
ORPHANET JOURNAL OF RARE DISEASES
(2022)
Article
Oncology
Elise Dumas, Lucie Laot, Florence Coussy, Beatriz Grandal Rejo, Eric Daoud, Enora Laas, Amyn Kassara, Alena Majdling, Rayan Kabirian, Floriane Jochum, Paul Gougis, Sophie Michel, Sophie Houzard, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Judicael Hotton, Chloe-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy
Summary: This study aimed to create a national cohort of French women diagnosed with early-stage breast cancer in order to promote cancer research and improve understanding of breast cancer. By aggregating and annotating administrative healthcare data, the study provides detailed descriptions and longitudinal trends of treatment pathways, adverse effects, care consumption, and basic characteristics of breast cancer patients.
Article
Oncology
Mary Katherine Anastasio, Anjali Gupta, Tomi F. Akinyemiju, Rebecca A. Previs
Summary: Disparities exist for Black patients with uterine cancer in terms of diagnosis, treatment, and survival. Black patients are more likely to have aggressive disease, receive less treatment, and have worse survival regardless of cancer subtype.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Memoli Victoria, Bannier Marie, Rey Dominique, Alleaume Caroline, Ben Diane Marc-Karim, Mancini Julien, Lauzier Sophie, Bouhnik Anne-Deborah
Summary: The study based on data from the national French cancer cohort VICAN found that older women and those with inadequate health literacy were less likely to undergo breast reconstruction (BR). BR was associated with better long-term physical quality of life, while immediate breast reconstruction (IBR) was associated with better mental quality of life.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Health Care Sciences & Services
Karl A. Lorenz, Jake Mickelsen, Nandini Vallath, Sushma Bhatnagar, Odette Spruyt, Michael Rabow, Meera Agar, Sydney M. Dy, Karen Anderson, Jayita Deodhar, Leela Digamurti, Gayatri Palat, Spandana Rayala, M. M. Sunilkumar, Vidya Viswanath, Jyothi Jayan Warrier, Sarbani Gosh-Laskar, Stephanie M. Harman, Karleen F. Giannitrapani, Anchal Satija, C. S. Pramesh, Michelle DeNatale
Summary: The Palliative Care-Promoting Access and Improvement of the Cancer Experience Program successfully built capacity in palliative care and cancer programs in India through international collaboration and training. It established a QI training hub in Mumbai, led national collaboratives and training, and integrated into India's National Cancer Grid.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Article
Oncology
Livia Costa de Oliveira, Karla Santos da Costa Rosa, Alessandra Zanei Borsatto, Luciana Aparecida Faria de Oliveira, Renata de Freitas, Simone Garruth dos Santos Machado Sampaio
Summary: This study described the overall survival in 90 days of patients with advanced cancer and COVID-19, and identified age, lung tumors, and chronic obstructive pulmonary disease as independent prognostic factors associated with higher risk of death.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Sophie Houzard, Emilie Courtois, Christine Le Bihan Benjamin, Marie Erbault, Laurent Arnould, Emmanuel Barranger, Florence Coussy, Benoit Couturaud, Bruno Cutuli, Patricia De Cremoux, Pia De Reilhac, Chantal De Seze, Aude-Marie Foucaut, Anne Gompel, Stephane Honore, Anne Lesur, Carole Mathelin, Laurent Verzaux, Philippe-Jean Bousquet
Summary: The French National Cancer Institute and the French National Authority for Health have developed breast cancer-specific Care Quality and Safety Indicators (BC QIs) to support local and national quality initiatives, improve breast cancer pathways and outcomes, and reduce practice heterogeneity and regional inequities. This study examines the BC QIs available in the French National medico-administrative cancer database for 2018.
CLINICAL BREAST CANCER
(2022)
Article
Health Care Sciences & Services
Sebastien Salas, Vanessa Pauly, Margaux Damge, Veronica Orleans, Guillaume Fond, Regis Costello, Laurent Boyer, Karine Baumstarck
Summary: This study investigates the management of end-of-life care for acute leukemia patients who died in the hospital. The findings show that a majority of patients received high-intensity end-of-life care. Younger age, comorbidities, care managed in specialized hospitals, and shorter time in palliative care structures were associated with higher intensity of end-of-life care.
BMC PALLIATIVE CARE
(2022)
Article
Engineering, Electrical & Electronic
Adedayo O. Aderibole, Erik K. Saathoff, Kevin J. Kircher, Aaron W. Langham, Leslie K. Norford, Steven B. Leeb
Summary: Electric power lines have the potential to create a widespread wired communication network for various devices. However, power line communication (PLC) faces challenges such as noise, signal attenuation, and unknown line impedances. This article introduces instrumentation that characterizes and verifies line characteristics for PLC applications, allowing for improved communication and adaptability to the local environment. Field experiments in a microgrid and apartment building demonstrate the reliability of a tailored PLC system in challenging locations.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Oncology
David Hui, Allison De La Rosa, Joseph Chen, Marvin Delgado Guay, Yvonne Heung, Seyedeh Dibaj, Diane Liu, Eduardo Bruera
Summary: The study compared the state of palliative care (PC) education and research between National Cancer Institute (NCI)-designated and nondesignated cancer centers in the US. Results showed that NCI-designated centers had more developed PC education and research programs compared to nondesignated centers. Progress in PC education and research has been slow and suboptimal overall, with few significant improvements observed between 2009 and 2018.
Article
Pediatrics
Candice Fabre, Caroline Thumerelle, Morgane Dervaux, Rola Abou-Taam, Tiphaine Bihouee, Jacques Brouard, Annick Clement, Christophe Delacourt, Celine Delestrain, Ralph Epaud, Sofiane Ghdifan, Alice Hadchouel, Veronique Houdouin, Geraldine Labouret, Caroline Perisson, Philippe Reix, Marie-Catherine Renoux, Francoise Troussier, Laurence Weiss, Julie Mazenq, Nadia Nathan, Jean-Christophe Dubus
Summary: The study aims to address the diagnosis and initial management of NEHI in pediatric centers for rare lung diseases. It found that NEHI diagnosis is often difficult and suggests the use of a composite clinical and radiological score to limit the use of anti-inflammatory drugs.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Medicine, General & Internal
Catherine J. Evans, Laura Potts, Ursula Dalrymple, Andrew Pring, Julia Verne, Irene J. Higginson, Wei Gao
Summary: This study examined patient characteristics and factors associated with mortality in adults admitted to intermediate care units in England. One in four patients died within 1 year, with respiratory conditions, dementia, liver disease, cancer, and increasing multimorbidity being indicators for palliative care assessment. The need for greater integration of palliative care in intermediate care units has been highlighted due to an aging population.
Article
Genetics & Heredity
Stephane Vignes, Juliette Albuisson, Laurence Champion, Joel Constans, Valerie Tauveron, Julie Malloizel, Isabelle Quere, Laura Simon, Maria Arrault, Patrick Trevidic, Philippe Azria, Annabel Maruani
Summary: Primary lymphedema is a rare chronic pathology mainly affecting the lower limbs, with women being more commonly affected than men. Diagnosis is primarily clinical and treatment aims to prevent complications, reduce volume, and stabilize the condition.
ORPHANET JOURNAL OF RARE DISEASES
(2021)
Article
Health Care Sciences & Services
Everlien de Graaf, Frederieke van der Baan, Matthew Paul Grant, Cathelijne Verboeket, Merel van Klinken, Adri Jobse, Marieke Ausems, Carlo Leget, Saskia Teunissen
Summary: Hospice care in the Netherlands is provided in three different types of facilities. The study aimed to characterize the patient populations accessing Dutch hospices and describe the patient profiles in different hospice types. The results showed that cancer patients are the majority and have various physical, psychological, social, and existential needs. There were no significant differences in patient needs between hospice types. Patients with non-malignant diseases and non-Dutch cultural backgrounds were less likely to access hospice care, and policies should focus on facilitating their involvement.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2022)
Article
Immunology
Sathish Kumar Deenadayalan, Kalpana Balakrishnan, Sundaramoorthy Chidambaram
Summary: This study aimed to assess the knowledge of diagnosis, prognosis, and psychological distress among patients in a palliative care department in a tertiary cancer hospital in south India. The results showed that a significant percentage of patients were unaware of their diagnosis and prognosis, and more than half reported significant distress. Higher educational levels and better socio-economic status increased the likelihood of patients being aware of their diagnosis and prognosis. Being unaware of the prognosis was associated with higher levels of distress.
INDIAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Oncology
Clement Magnani, Allan Ben Smith, Dominique Rey, Aline Sarradon-Eck, Marie Preau, Marc-Karim Bendiane, Anne-Deborah Bouhnik, Julien Mancini
Summary: This study aimed to estimate the prevalence of fear of cancer recurrence (FCR) in young women diagnosed with a good-prognosis cancer 5 years after diagnosis. The results showed that nearly 20% of female long-term survivors experienced moderate/severe FCR. Factors associated with FCR included cancer-related treatment sequelae, fatigue, anxiety, breast cancer or melanoma (versus thyroid cancer), and occasional consultation with a general practitioner.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Computer Science, Information Systems
Rajae Touzani, Emilien Schultz, Stephanie Vandentorren, Pierre Arwidson, Francis Guillemin, Anne-Deborah Bouhnik, Alexandra Rouquette, Julien Mancini
Summary: This study estimated the proportion of users of the TousAntiCovid app and identified factors associated with its non-use for contact tracing in France. Among 1,000 respondents, 63.3% had never downloaded the app, 23.5% used it for contact tracing. Reasons for not enabling contact tracing included excessive battery consumption and fear of personal data misuse. Trust in political representatives, financial deprivation, and other factors were associated with never downloading the app.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2023)
Article
Genetics & Heredity
F. Gauna, S. Carof, E. Mouret-Fourme, I. Coupier, V. Mari, J. Moretta-Serra, J. Mancini, C. Nogues, A. D. Bouhnik
Summary: This qualitative study examined how parents carrying BRCA1/2 pathogenic variants communicate cancer and genetic risk information to their children. Findings revealed the influence of gender norms on parents' communication practices, with women being more attentive to both their own health and their loved ones' health.
JOURNAL OF GENETIC COUNSELING
(2023)
Article
Health Care Sciences & Services
Rajae Touzani, Elodie Dembele, Emilien Schultz, Alexandra Rouquette, Lorene Sequin, Jean -Charles Dufour, Marie Bannier, Julien Mancini
Summary: The study aimed to understand the perception among the general population in France regarding the usefulness of video recording/broadcasting and mobile health apps for medical consultations during the COVID-19 health crisis. The majority of respondents considered mobile health apps useful, while a smaller percentage considered video recording/broadcasting to be useful. Factors associated with perceived usefulness included younger age, trust in political representatives, and higher health literacy. It is important to consider these perceptions to ensure accessibility and benefits for all.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Acoustics
Maud Regouin, Julien Mancini, Antoine Lafouge, Pierre Mace, Nathalie Fontaine, Stephanie Roussin, Jimmy Guichard, Coralie Dumont, Edwin Quarello
Summary: The objective of this study was to define quality criteria for fetal LVOT assessment and to evaluate the impact of implementing these criteria on practice. The study found that LVOT pictures were present in over 94.3% of reports, and there was no significant change in practice following the introduction of the quality criteria.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Meeting Abstract
Oncology
J. Mancini
Article
Oncology
Anne-Laure Couderc, Anne-Deborah Bouhnik, Dominique Rey, Marc-Karim Bendiane, Laurent Greillier, Eillier Nouguerede, Ariane Pille, Coline Montegut, Frederique Rousseau, Patrick Villani, Julien Mancini
Summary: This study aimed to describe the quality of life of lung cancer survivors five years after diagnosis, comparing older survivors (aged 70 or above) with younger ones, and identifying factors associated with poorer long-term quality of life in both age groups. The results showed that physical and mental factors had a greater impact on the quality of life of older survivors, while younger survivors were more influenced by factors such as gender, cancer metastasis, neuropathic pain, and breathing difficulties.
Article
Public, Environmental & Occupational Health
Martin Breyton, Emilien Schultz, Allan 'Ben' Smith, Alexandra Rouquette, Julien Mancini
Summary: This study assessed the psychometric properties of the Coronavirus Information Overload scale (CovIO) and explored its relationships with predictors and health behaviors related to COVID-19. The CovIO scale showed satisfactory properties and was significantly linked to education, health literacy, and trust in institutions among other variables. A negative relationship between information overload and preventive behaviors was observed.
PATIENT EDUCATION AND COUNSELING
(2023)
Article
Public, Environmental & Occupational Health
Emilien Schultz, Julien Mancini, Jeremy K. Ward
Summary: Conflicts of interests in health and medicine have been a topic of public debate for a long time. While there has been analysis of policies regulating the relationships between medical researchers and private corporations, little attention has been given to how the public defines and uses the label of conflict of interest. This article explores the French public's perception of conflict of interest for medical researchers through a questionnaire survey, and identifies three main groups with different conceptions of what constitutes a conflict of interest.
SOCIAL SCIENCE & MEDICINE
(2023)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Kawtar Debbi, Amine Bouachba, Julien Mancini, Lucile Tuchtan, Joana De Jesus Neves, Guillaume Gorincour
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2023)
Article
Obstetrics & Gynecology
Lea Morello, Julien Mancini, Xavier Carcopino
Summary: Objectives: To identify predictive factors of the absence of high-grade intraepithelial lesion (HGSIL) in cervical excisional therapy specimen. Methods: Retrospective analysis of data from 835 women who underwent excisional therapy for a cervical intraepithelial lesion at two university hospitals. Results: Factors significantly associated with the absence of HGSIL on cervical excisional specimen included age over 40 years, a small abnormal transformation zone (TZ), and the result of the cervical biopsy not showing HGSIL. Referral cytology and colposcopic impression did not have a significant impact. Conclusion: The result of cervical biopsy is the key risk factor for the absence of HGSIL on excisional specimen, with age over 40 and a small abnormal TZ as additional risk factors.
JOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTION
(2023)
Article
Cardiac & Cardiovascular Systems
Amedeo Anselmi, Jacques Tomasi, Marie Aymami, Julien Mancini, Nicolas Nesseler, Thierry Langanay, Erwan Flecher, Jean-Philippe Verhoye
Summary: This study investigated the long-term durability of the Epic bioprosthesis for surgical aortic valve replacement (SAVR) and found that it has excellent durability and low rates of adverse valve-related events.
JOURNAL OF CARDIOVASCULAR MEDICINE
(2023)
Article
Oncology
Agnes Tallet, Dominique Rey, Clemence Casanova, Delphine Lecourtois, Marie Bergeaud, Marc-Karim Bendiane, Julien Mancini
Summary: This qualitative study explored the perspectives of physicians on intraoperative radiotherapy (IORT) as a de-escalation option for older women with low-risk early breast cancer. The study found divergent opinions among physicians, with some fully supporting IORT, some opposing it, and others having a reserved or neutral opinion. The divergent opinions were related to treatment efficacy, duration, side effects, psychological impact, compliance, logistical issues, cost, and availability of alternative treatment techniques, indicating a need for further efforts to promote patient-centered care.
