Methods to Optimize CNS Exposure of Drug Candidates
Authors
Keywords
Blood Brain Barrier (BBB), Brain availability, Madin-Darby canine kidney (MDCK), Multi-drug resistance protein 1 (MDR1), Breast Cancer Resistant Protein (BCRP), Central nervous system (CNS), Efflux ratio (ER), Cerebrospinal fluid (CSF), In vitro, to , in vivo, correlation (IVIVC)
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