Recent advances in microfluidic technologies for separation of biological cells

Past, Present, and Future of Affinity-based Cell Separation Technologies

(2020) Kaitlyn Bacon et al.   Acta Biomaterialia

Multi-level separation of particles using acoustic radiation force and hydraulic force in a microfluidic chip

(2019) Guojun Liu et al.   Microfluidics and Nanofluidics

Multi-Stage Particle Separation based on Microstructure Filtration and Dielectrophoresis

(2019) Danfen Yin et al.   Micromachines

Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement

(2019) Nan Xiang et al.   ANALYTICAL CHEMISTRY

CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)

(2019) Tayoun et al.   Cells

Optical and electrochemical-based nano-aptasensing approaches for the detection of circulating tumor cells (CTCs)

(2019) Hossein Safarpour et al.   BIOSENSORS & BIOELECTRONICS

Detection of sepsis in patient blood samples using CD64 expression in a microfluidic cell separation device

(2018) Ye Zhang et al.   ANALYST

Spiral shape microfluidic channel for selective isolating of heterogenic circulating tumor cells

(2018) Bongseop Kwak et al.   BIOSENSORS & BIOELECTRONICS

A simplified sheathless cell separation approach using combined gravitational-sedimentation-based prefocusing and dielectrophoretic separation

(2018) Tao Luo et al.   LAB ON A CHIP

Sorting of tumour cells in a microfluidic device by multi-stage surface acoustic waves

(2018) Kaiyue Wang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Arrayed microfluidic chip for detection of circulating tumor cells and evaluation of drug potency

(2018) Xuejia Huang et al.   ANALYTICAL BIOCHEMISTRY

An Optically Induced Dielectrophoresis (ODEP)-Based Microfluidic System for the Isolation of High-Purity CD45neg/EpCAMneg Cells from the Blood Samples of Cancer Patients—Demonstration and Initial Exploration of the Clinical Significance of These Cells

(2018) Chia-Jung Liao et al.   Micromachines

Enhanced isolation and release of fetal nucleated red blood cells using multifunctional nanoparticle-based microfluidic device for non-invasive prenatal diagnostics

(2018) Xiaoyun Wei et al.   SENSORS AND ACTUATORS B-CHEMICAL

Enhanced surface acoustic wave cell sorting by 3D microfluidic-chip design

(2017) W. L. Ung et al.   LAB ON A CHIP

Fabrication of large-area polymer microfilter membranes and their application for particle and cell enrichment

(2017) Javier Alejandro Hernández-Castro et al.   LAB ON A CHIP

Concentration and extraction chip of fetal nucleated red blood Cells (NRBCs) by micro gap with diaphragm for fetal DNA diagnosis from maternal blood

(2017) Takeshi Kumo et al.   MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS

Dielectrophoretic Separation of Live and Dead Monocytes Using 3D Carbon-Electrodes

(2017) Yagmur Yildizhan et al.   SENSORS

Label-free Rapid Viable Enrichment of Circulating Tumor Cell by Photosensitive Polymer-based Microfilter Device

(2017) Yoon-Tae Kang et al.   Theranostics

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells

(2017) Fabio Fachin et al.   Scientific Reports

Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis

(2016) Bongkot Ngamsom et al.   ANALYTICA CHIMICA ACTA

Highly Localized Acoustic Streaming and Size-Selective Submicrometer Particle Concentration Using High Frequency Microscale Focused Acoustic Fields

(2016) David J. Collins et al.   ANALYTICAL CHEMISTRY

Mechanical Properties Based Particle Separation via Traveling Surface Acoustic Wave

(2016) Zhichao Ma et al.   ANALYTICAL CHEMISTRY

Fifty years of dielectrophoretic cell separation technology

(2016) Michael P. Hughes   Biomicrofluidics

Hybrid microfluidics combined with active and passive approaches for continuous cell separation

(2016) Sheng Yan et al.   ELECTROPHORESIS

High frequency travelling surface acoustic waves for microparticle separation

(2016) Ghulam Destgeer et al.   Journal of Mechanical Science and Technology

Thermally-assisted ultrasonic separation of giant vesicles

(2016) Ata Dolatmoradi et al.   LAB ON A CHIP

Does the mobilization of circulating tumour cells during cancer therapy cause metastasis?

(2016) Olga A. Martin et al.   Nature Reviews Clinical Oncology

Advanced Materials for the Recognition and Capture of Whole Cells and Microorganisms

(2015) Amanda L. Bole et al.   ADVANCED MATERIALS

Label-Free Isolation and mRNA Detection of Circulating Tumor Cells from Patients with Metastatic Lung Cancer for Disease Diagnosis and Monitoring Therapeutic Efficacy

(2015) Jidong Wang et al.   ANALYTICAL CHEMISTRY

Tapered-slit membrane filters for high-throughput viable circulating tumor cell isolation

(2015) Yoon-Tae Kang et al.   BIOMEDICAL MICRODEVICES

Antibody-free isolation of rare cancer cells from blood based on 3D lateral dielectrophoresis

(2015) I-Fang Cheng et al.   LAB ON A CHIP

Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

(2015) C. Wyatt Shields IV et al.   LAB ON A CHIP

Acoustic separation of circulating tumor cells

(2015) Peng Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput rare cell separation from blood samples using steric hindrance and inertial microfluidics

(2014) Shaofei Shen et al.   LAB ON A CHIP

Submicron separation of microspheres via travelling surface acoustic waves

(2014) Ghulam Destgeer et al.   LAB ON A CHIP

Continuous-flow microfluidic blood cell sorting for unprocessed whole blood using surface-micromachined microfiltration membranes

(2014) Xiang Li et al.   LAB ON A CHIP

Deterministic lateral displacement for particle separation: a review

(2014) J. McGrath et al.   LAB ON A CHIP

Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates

(2013) Qinglin Shen et al.   ADVANCED MATERIALS

Separation of Escherichia coli Bacteria from Peripheral Blood Mononuclear Cells Using Standing Surface Acoustic Waves

(2013) Ye Ai et al.   ANALYTICAL CHEMISTRY

A pillar-based microfilter for isolation of white blood cells on elastomeric substrate

(2013) Jafar Alvankarian et al.   Biomicrofluidics

High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) force

(2013) Song-Bin Huang et al.   LAB ON A CHIP

Surface acoustic wave microfluidics

(2013) Xiaoyun Ding et al.   LAB ON A CHIP

Continuous separation of particles in a PDMS microfluidic channel via travelling surface acoustic waves (TSAW)

(2013) Ghulam Destgeer et al.   LAB ON A CHIP

Microchannel Acoustophoresis does not Impact Survival or Function of Microglia, Leukocytes or Tumor Cells

(2013) Miguel A. Burguillos et al.   PLoS One

Continuous Cell Separation Using Dielectrophoresis through Asymmetric and Periodic Microelectrode Array

(2012) Siang Hooi Ling et al.   ANALYTICAL CHEMISTRY

Acoustophoretic Sorting of Viable Mammalian Cells in a Microfluidic Device

(2012) Allen H. J. Yang et al.   ANALYTICAL CHEMISTRY

“Overpass” at the junction of a crossed microchannel: An enabler for 3D microfluidic chips

(2012) Yan He et al.   LAB ON A CHIP

Acoustofluidics 8: Applications of acoustophoresis in continuous flow microsystems

(2012) Andreas Lenshof et al.   LAB ON A CHIP

Microfluidic approaches for cancer cell detection, characterization, and separation

(2012) Jian Chen et al.   LAB ON A CHIP

Microfluidic devices in superconducting magnets: on-chip free-flow diamagnetophoresis of polymer particles and bubbles

(2012) Martin Vojtíšek et al.   Microfluidics and Nanofluidics

Bioinspired multivalent DNA network for capture and release of cells

(2012) W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Velocity Effect on Aptamer-Based Circulating Tumor Cell Isolation in Microfluidic Devices

(2011) Yuan Wan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP)

(2011) Hui-Sung Moon et al.   LAB ON A CHIP

Microchip-based immunomagnetic detection of circulating tumor cells

(2011) Kazunori Hoshino et al.   LAB ON A CHIP

Recent advances in particle and droplet manipulation for lab-on-a-chip devices based on surface acoustic waves

(2011) Zhuochen Wang et al.   LAB ON A CHIP

Size-dependent microparticles separation through standing surface acoustic waves

(2011) Jeonghun Nam et al.   Microfluidics and Nanofluidics

Efficient Removal of Platelets from Peripheral Blood Progenitor Cell Products Using a Novel Micro-Chip Based Acoustophoretic Platform

(2011) Josefina Dykes et al.   PLoS One

Manipulation of Magnetically Labeled and Unlabeled Cells with Mobile Magnetic Traps

(2010) T. Henighan et al.   BIOPHYSICAL JOURNAL

Adhesion based detection, sorting and enrichment of cells in microfluidic Lab-on-Chip devices

(2010) Tohid Fatanat Didar et al.   LAB ON A CHIP

Enhanced Tumor Cell Isolation by a Biomimetic Combination of E-selectin and anti-EpCAM: Implications for the Effective Separation of Circulating Tumor Cells (CTCs)

(2010) Ja Hye Myung et al.   LANGMUIR

Microfluidics for cell separation

(2010) Ali Asgar S. Bhagat et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

(2010) S. L. Stott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach

(2009) Xiaohong Fang et al.   ACCOUNTS OF CHEMICAL RESEARCH

On-Chip Fluorescence-Activated Cell Sorting by an Integrated Miniaturized Ultrasonic Transducer

(2009) Linda Johansson et al.   ANALYTICAL CHEMISTRY

Aptamer-Based Microfluidic Device for Enrichment, Sorting, and Detection of Multiple Cancer Cells

(2009) Ye Xu et al.   ANALYTICAL CHEMISTRY

Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer

(2009) F. Tanaka et al.   CLINICAL CANCER RESEARCH

Soft inertial microfluidics for high throughput separation of bacteria from human blood cells

(2009) Zhigang Wu et al.   LAB ON A CHIP

Continuous particle separation in a microfluidic channel via standing surface acoustic waves (SSAW)

(2009) Jinjie Shi et al.   LAB ON A CHIP

Inertial microfluidics for continuous particle separation in spiral microchannels

(2009) Sathyakumar S. Kuntaegowdanahalli et al.   LAB ON A CHIP

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Equilibrium Separation and Filtration of Particles Using Differential Inertial Focusing

(2008) Dino Di Carlo et al.   ANALYTICAL CHEMISTRY

Separation enhancement in pinched flow fractionation

(2008) Asger Laurberg Vig et al.   APPLIED PHYSICS LETTERS

Continuous focusing of microparticles using inertial lift force and vorticity via multi-orifice microfluidic channels

(2008) Jae-Sung Park et al.   LAB ON A CHIP

A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women

(2008) R. Huang et al.   PRENATAL DIAGNOSIS