Challenges in clinical trials for children and young people

Improved infrastructure and support needed for paediatric clinical trials in Sweden

(2020) H Mattsson et al.   ACTA PAEDIATRICA

Characteristics of parental decision-making for children with advanced cancer who are offered enrollment in early-phase clinical trials: A systematic review

(2020) Marie-Amelyne Le Rouzic et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

Neonatal Therapeutics: Considerations for Dosing

(2019) Kanecia O. Zimmerman et al.   AMERICAN JOURNAL OF PERINATOLOGY

Promoting Pediatric Drug Research and Labeling — Outcomes of Legislation

(2019) Florence T. Bourgeois et al.   NEW ENGLAND JOURNAL OF MEDICINE

Barriers and facilitators to clinical trial participation among parents of children with pediatric neuromuscular disorders

(2018) Holly L Peay et al.   Clinical Trials

Assessing Drug Safety in Children — The Role of Real-World Data

(2018) Ann W. McMahon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Two decades of off-label prescribing in children: a literature review

(2018) Shamala Balan et al.   World Journal of Pediatrics

Enabling Development of Paediatric Medicines in Europe: 10 Years of the EU Paediatric Regulation

(2017) Paolo A. Tomasi et al.   PEDIATRIC DRUGS

Resource expectations for pediatric studies: Correlation of study type and patient number for FDA labeling

(2017) S. Hirschfeld   JOURNAL OF CLINICAL ONCOLOGY

Discontinuation and Nonpublication of Randomized Clinical Trials Conducted in Children

(2016) N. Pica et al.   PEDIATRICS

Adaptive design of confirmatory trials: Advances and challenges

(2015) Tze Leung Lai et al.   Contemporary Clinical Trials

Ethical Considerations in Conducting Pediatric and Neonatal Research in Clinical Pharmacology

(2015) Michelle Roth-Cline et al.   CURRENT PHARMACEUTICAL DESIGN

Safety of medicines used for ADHD in children: a review of published prospective clinical trials

(2014) A. Clavenna et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Off-Label Use of Drugs in Children

(2014) et al.   PEDIATRICS

Use of data from registered clinical trials to identify gaps in health research and development

(2013) Roderik F Viergever et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Biomarker-based adaptive trials for patients with glioblastoma--lessons from I-SPY 2

(2013) B. M. Alexander et al.   NEURO-ONCOLOGY

Placebo effects in children: a review

(2013) Katja Weimer et al.   PEDIATRIC RESEARCH

Paediatric drug use with focus on off-label prescriptions at Swedish hospitals - a nationwide study

(2012) E Kimland et al.   ACTA PAEDIATRICA

Pediatric Versus Adult Drug Trials for Conditions With High Pediatric Disease Burden

(2012) F. T. Bourgeois et al.   PEDIATRICS

Paediatric drug use with focus on off-label prescriptions in Swedish outpatient care - a nationwide study

(2011) J Olsson et al.   ACTA PAEDIATRICA

Prescribing of medicines in the Danish paediatric population outwith the licensed age group: characteristics of adverse drug reactions

(2011) Lise Aagaard et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effects of Depot Medroxyprogesterone Acetate and 20-Microgram Oral Contraceptives on Bone Mineral Density

(2010) Abbey B. Berenson et al.   OBSTETRICS AND GYNECOLOGY

Greater Response to Placebo in Children Than in Adults: A Systematic Review and Meta-Analysis in Drug-Resistant Partial Epilepsy

(2008) Sylvain Rheims et al.   PLOS MEDICINE