Review
Allergy
Clara Westwell-Roper, Sharon To, Gordan Andjelic, Cynthia Lu, Boyee Lin, Lianne Soller, Edmond S. Chan, S. Evelyn Stewart
Summary: Parenting a child with food allergy can lead to impaired quality of life and family functioning, with anxiety being a critical component of distress. Existing measures for general anxiety symptoms and FA-specific parental factors fail to adequately capture dimensions of FA-specific anxiety, suggesting the need for further improvement in assessment and monitoring of FAA.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Allergy
Alice Hu, Melanie Lloyd, Paxton Loke, Adriana Chebar Lozinsky, Michael O'Sullivan, Patrick Quinn, Michael Gold, Mimi L. K. Tang
Summary: There are associations between reaction eliciting dose (ED) and the nature of allergic symptoms with HRQoL among children with peanut allergy. Gastrointestinal symptoms, lower airway symptoms, multisystem involvement, and anaphylaxis are associated with worse HRQoL. Increased clinical support and interventions are needed for children experiencing these symptoms and those with lower reaction ED.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Pediatrics
Kristin N. Ray, Anna K. Ettinger, Namita Dwarakanath, Sejal Mistry, Jamil Bey, Diego Chaves-Gnecco, Kaila A. Alston, Lisa Ripper, Daniel R. Lavage, Douglas P. Landsittel, Elizabeth Miller
Summary: The study found that over half of families with children reported unmet health or social service needs during the first month of a county-wide COVID-19 stay-at-home order in Western Pennsylvania. Unmet needs varied with race, ethnicity, income, and the duration of the stay-at-home order.
ACADEMIC PEDIATRICS
(2021)
Article
Allergy
Agnes Sze Yin Leung, Nam Sze Cheng, Rebecca Ming Yan Li, Pui Fung Li, Yat Laam Lee, Tik Wai Fu, Bertine Flokstra-de Blok, Ting Fan Leung
Summary: This study validated the Food Allergy Quality of Life Questionnaire (FAQLQ) series in Chinese food-allergic patients and caregivers, except for parents of children aged 0-3 years. Items in the questionnaires were categorized into different functional domains in the study population.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Allergy
Agnes Sze Yin Leung, Nam Sze Cheng, Rebecca Ming Yan Li, Pui Fung Li, Yat Laam Lee, Tik Wai Fu, Bertine Flokstra-de Blok, Ting Fan Leung
Summary: This study validates the Food Allergy Quality of Life Questionnaire (FAQLQ) series in Chinese food-allergic patients and caregivers, except for parents of children aged 0-3 years. The FAQLQ series provides a valid and reliable measure for Quality of Life (QoL) in this population, with items categorized into different functional domains.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Minyoung Jung, Urim Kang, Sukyung Kim, Hye Won Yoo, Hye-Young Kim, Minji Kim, Ji Young Lee, KyooSang Kim, Eunsun Lee, Byoung-Chul Kang, Boram Park, Kangmo Ahn, Jihyun Kim
Summary: This study aimed to validate the Korean version of the Food Allergy Quality of Life-Parental Burden (FAQL-PB) and identify factors related to the parental psychosocial burden of caring for children with food allergies. The results showed that social activity limitation was the key factor contributing to higher FAQL-PB scores. The analysis indicated a positive correlation between parental burden, anxiety, and depression, while resilience was inversely correlated with parental burden.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Allergy
Montserrat Fernandez-Rivas, Andrea Vereda, Brian P. Vickery, Vibha Sharma, Caroline Nilsson, Antonella Muraro, Jonathan O'b Hourihane, Audrey DunnGalvin, George Toit, Katharina Blumchen, Kirsten Beyer, Alex Smith, Robert Ryan, Daniel C. Adelman, Stacie M. Jones
Summary: The study demonstrates that daily treatment with PTAH for peanut allergies beyond 1 year leads to improved safety and tolerability, as well as sustained clinical and immunological responses.
Article
Allergy
Katsumasa Kitamura, Kazunori Sakai, Kemal Sasaki, Teruaki Matsui, Yoshihiro Takasato, Shiro Sugiura, Komei Ito
Summary: The study compared two dietary instruction methods for introducing egg to children with suspected egg allergy and found that the step-up OFC testing (SOFT) method was more effective than home incrementing. Additionally, parental anxiety significantly improved during treatment in both groups.
ALLERGOLOGY INTERNATIONAL
(2021)
Article
Nutrition & Dietetics
Fumiko Okazaki, Hiroyuki Wakiguchi, Yuno Korenaga, Kazumasa Takahashi, Hiroki Yasudo, Ken Fukuda, Mototsugu Shimokawa, Shunji Hasegawa
Summary: Little is known about the clinical features of food protein-induced enterocolitis syndrome (FPIES) in patients with Down syndrome (DS). This study found that FPIES in DS patients is associated with greater severity and earlier onset of symptoms. Cow's milk formula and wheat were the main causative foods. The surgical history of colostomy and postoperative nutrition may contribute to the onset of FPIES. Therefore, the use of amino acid-based formula should be considered for DS children undergoing gastrointestinal surgeries, and FPIES should be considered when acute gastrointestinal disease is suspected in DS children.
Article
Clinical Neurology
Lei Wang, Yeerzhati Yeerjiang, Hai Feng Gao, Jian Feng Pei, Ruo Xin Zhang, Wang Hong Xu
Summary: The outbreak of COVID-19 has increased anxiety levels among senior high school students in China. Factors such as gender, academic year, academic performance, attitude towards medical study, residence in Hubei province, and acquaintance infected with COVID-19 are significantly associated with anxiety levels.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Public, Environmental & Occupational Health
Matthew P. Rabbitt, Matthew R. Beymer, Joanna J. Reagan, Brantley P. Jarvis, Eren Y. Watkins
Summary: This study examined the factors contributing to food insecurity among active duty Army households during the COVID-19 pandemic. The findings showed that Army households experienced a significant increase in marginal food insecurity during the pandemic, and those who transitioned into food insecurity were more concerned about financial and job security compared to those who remained highly food secure.
PUBLIC HEALTH NUTRITION
(2022)
Article
Allergy
Cecile Frachette, Agnes Fina, Eric Fontas, Dominique Donzeau, Marie Hoflack, Frederique Gastaud, Elisabeth Baechler, Emmanuelle Dor, Bruno Descos, Valerie Triolo, Stephanie Berthet, Carole Bailly-Piccini, Melissa Beguin, Bertine Flokstra-de Blok, Thierry Bourrier, Lisa Giovannini-Chami
Summary: The study aimed to assess the health-related quality of life (HRQL) of food-allergic patients compared to the general population and those with other chronic diseases. Results showed that food-allergic patients had better HRQL in certain domains compared to healthy controls and other chronic disease patients, but had poorer overall health perception. While most food-allergic children had been prescribed an epinephrine autoinjector, only slightly over half of them carried it with them at all times.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Review
Pediatrics
Artemis-Eirini Drakouli, Ioanna Kontele, Dimitrios Poulimeneas, Stella Saripanagiotou, Maria G. Grammatikopoulou, Theodoros N. Sergentanis, Tonia Vassilakou
Summary: Recently, there has been an increased focus on the psychosocial aspects of food allergy (FA) in addition to medical diagnosis and treatment. This systematic review examined the scientific evidence on Health-Related Quality of Life (HRQoL) among children and adolescents with FAs from January 2015 to April 2022. The review included 28 research studies from three databases and found that most children and adolescents with FAs had average levels of HRQoL, with girls and older children experiencing more negative impacts. Few studies compared HRQoL between children with FA and healthy children, but some showed worse HRQoL for children with FAs. Immunotherapy was found to improve the QoL of children with FAs, while factors such as anaphylaxis history and severity of symptoms negatively impacted QoL. More comparative studies are needed to improve the QoL of children with FAs.
Article
Nutrition & Dietetics
Guifeng Xu, Buyun Liu, Wenhan Yang, Linda G. Snetselaar, Mingwu Chen, Wei Bao, Lane Strathearn
Summary: This study found a significant association of common allergic conditions (food allergy, respiratory allergy, and skin allergy) with ADHD in a nationally representative sample of US children aged 4-17 years.
Article
Allergy
Zoe Morou, Emilia Vassilopoulou, Petros Galanis, Athina Tatsioni, Nikolaos G. Papadopoulos, Ioannis D. K. Dimoliatis
Summary: This study aimed to evaluate the relationship between food allergy characteristics in primary school children and health-related quality of life. However, most of the characteristics showed no correlation with quality of life scores, and no significant associations were found in the multivariate analysis.
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
(2021)
Review
Allergy
Jaclyn Bjelac, Elissa M. Abrams, Edward G. A. Iglesia
Summary: Food allergy is a significant public health concern, including during travel. This scoping review explores the management of food allergy while traveling. The review identifies priorities for patients and their allergist-immunologist, such as managing reactions, access to emergency services, cross-contact risks, and language barriers during international travel. It emphasizes the need for careful planning and preparation for food allergy patients to ensure access to safe food and emergency medication while away from home.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2023)
Article
Immunology
Adnan Al Ali, Sofianne Gabrielli, Luca Delli Colli, Marina Delli Colli, Christine McCusker, Ann E. Clarke, Judy Morris, Jocelyn Gravel, Rodrick Lim, Edmond S. Chan, Ran D. Goldman, Andrew O'Keefe, Jennifer Gerdts, Derek K. Chu, Julia Upton, Elana Hochstadter, Jocelyn Moisan, Adam Bretholz, Xun Zhang, Jennifer L. P. Protudjer, Elissa M. Abrams, Elinor Simons, Moshe Ben-Shoshan
Summary: This study evaluated the trends in anaphylaxis rates in a pediatric Emergency Department in Montreal, Canada over the past decade. The study found that the rate of anaphylaxis doubled between 2011 and 2015, but decreased during the COVID-19 pandemic. This may be attributed to changes in food introduction strategies or lifestyle, as well as reduced social gatherings, school closures, and reluctance to seek medical care during the pandemic.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
(2023)
Editorial Material
Pediatrics
Denise Ridley, Elissa M. Abrams, Peter Wong, Edmond S. Chan
Summary: The Canadian Paediatric Society's Position statement on allergy prevention in high-risk infants recommends regular ingestion of cow's milk protein based on evidence from controlled trials. However, this commentary highlights the challenges in implementing these recommendations in real life situations and offers alternative options.
PAEDIATRICS & CHILD HEALTH
(2023)
Review
Allergy
Marcus Shaker, Elissa M. Abrams, J. Wesley Sublett
Summary: Prompt administration of epinephrine is important for treating anaphylaxis. Multiple epinephrine devices may not be necessary for all patients at risk for allergic reactions.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2023)
Editorial Material
Allergy
Elissa M. Abrams, Jennifer L. P. Protudjer
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2023)
Review
Allergy
Matthew Greenhawt, Timothy E. Dribin, Elissa M. Abrams, Marcus Shaker, Derek K. Chu, David B. K. Golden, Cem Akin, Akterini Anagnostou, Faisal Almuhizi, Waleed Alqurashi, Peter Arkwright, James L. Baldwin, Aleena Banerji, Philippe Begin, Moshe Ben-Shoshan, Jonathan Bernstein, Theresa A. Bingemann, Carsten Bindslev-Jensen, Kim Blumenthal, Aideen Byrne, Julia Cahill, Scott Cameron, Dianne Campbell, Ronna Campbell, Michael Cavender, Edmond S. Chan, Sharon Chinthrajah, Pasquale Comberiati, Jacqueline J. Eastman, Anne K. Ellis, David M. Fleischer, Adam Fox, Pamela A. Frischmeyer-Guerrerio, Remi Gagnon, Lene H. Garvey, Mitchell H. Grayson, Ghislaine Annie Clarisse Isabwe, Nicholas Hartog, David Hendron, Caroline C. Horner, Johnathan O'B Hourihane, Edward Iglesia, Manstein Kan, Blanka Kaplan, Constance H. Katelaris, Harold Kim, John M. Kelso, David A. Khan, David Lang, Dennis Ledford, Michael Levin, Jay A. Lieberman, Richard Loh, Douglas P. Mack, Bruce Mazer, Ketan Mody, Gisele Mosnaim, Daniel Munblit, S. Shahzad Mustafa, Anil Nanda, Richard Nathan, John Oppenheimer, Iris M. Otani, Miguel Park, Ruby Pawankar, Kirsten P. Perrett, Jonny Peter, Elizabeth J. Phillips, Matthieu Picard, Mitchell Pitlick, Allison Ramsey, Trine Holm Rasmussen, Melinda M. Rathkopf, Hari Reddy, Kara Robertson, Pablo Rodriguez del Rio, Stephen Sample, Ajay Sheshadri, Javed Sheik, Sayantani B. Sindher, Jonathan M. Spergel, Cosby A. Stone, David Stukus, Mimi L. K. Tang, James M. Tracy, Paul J. Turner, Timothy K. Vander Leek, Dana V. Wallace, Julie Wang, Susan Wasserman, David Weldon, Anna R. Wolfson, Margitta Worm, Mona-Rita Yacoub
Summary: This guidance provides updates on immediate allergic reactions following COVID-19 vaccines, including recommendations for revaccinating individuals with first-dose allergic reactions and conducting allergy testing. The recommendations were formed by an international panel of experts and are based on recent meta-analyses and diagnostic accuracy studies.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Editorial Material
Critical Care Medicine
Elissa M. Abrams, Joseline G. Zafack, Shainoor J. Ismail, Julie A. Bettinger, Kyla J. Hildebrand, Matthew C. Tunis
LANCET RESPIRATORY MEDICINE
(2023)
Letter
Allergy
Gilbert T. Chua, Matthew Greenhawt, Marcus Shaker, Lianne Soller, Elissa M. Abrams, Scott B. Cameron, Victoria E. Cook, Stephanie C. Erdle, David M. Fleischer, Raymond Mak, Timothy K. Vander, Edmond S. Chan
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Allergy
Albert C. Chong, Lavanya Diwakar, Cameron M. Kaplan, Adam T. Fox, Elissa M. Abrams, Matthew Greenhawt, John J. Oppenheimer, Marcus S. Shaker
Summary: Food allergy is a growing issue worldwide, with increasing prevalence in high-income countries like the United Kingdom and United States. This review compares the delivery of food allergy care in these two countries and discusses their responses to the demand for services. In the United Kingdom, general practitioners provide most allergy care due to a scarcity of allergy specialists, while the United States has more allergists per capita but still faces a shortage of allergy services. Both countries aim to increase the number of specialists and improve the quality of care, but further efforts are needed to reduce disparities in access to care, such as building clinical networks and expanding telehealth services.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Letter
Allergy
Michael A. Golding, Leslie E. Roos, Elissa M. Abrams, Jennifer D. Gerdts, Jennifer L. P. Protudjer
Summary: This study investigated the food security situation of Canadian families with pediatric food allergy. The research found that the rate of food insecurity was 22.9% in the year prior to the COVID-19 pandemic, but increased to 74.4% during the pandemic.
ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY
(2023)
Article
Allergy
Hannah Stirton, Leanne Kosowan, Elissa M. Abrams, Jennifer L. P. Protudjer, John Queenan, Alexander Singer
Summary: This study validated case definitions for eczema using primary care Electronic Medical Record (EMR) data in Canada. Different case definitions were assessed for their agreement statistics, and the most sensitive and specific ones were then applied to estimate the prevalence of eczema in the country.
ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY
(2023)
Review
Pediatrics
Elissa M. Abrams, Marcus S. Shaker, Edmond S. Chan, Helen A. Brough, Matthew Greenhawt
Summary: There is increasing focus on the role of maternal interventions in preventing food allergy in infants. Dietary modifications during pregnancy or lactation, such as allergen avoidance, do not prevent infant allergies. While exclusive breastfeeding is globally recommended, its effect on preventing infant allergies is still unclear. There is emerging evidence that irregular exposure to cow's milk may increase the risk of cow's milk allergy. Additionally, there is emerging evidence that maternal peanut ingestion during breastfeeding and early peanut introduction in infancy may have a preventive role. The effect of maternal dietary supplementation with vitamin D, omega-3, and prebiotics or probiotics remains unclear.
LANCET CHILD & ADOLESCENT HEALTH
(2023)
Letter
Allergy
Michael A. Golding, Lianne Soller, Jennifer L. P. Protudjer, Edmond S. Chan
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Editorial Material
Allergy
Elissa M. Abrams, Moshe Ben-Shoshan, Jennifer L. P. Protudjer, Elana Lavine, Edmond S. Chan
ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY
(2023)
Review
Allergy
Matthew Greenhawt, Marcus Shaker, David B. K. Golden, Elissa M. Abrams, Kimberly G. Blumenthal, Anna R. Wolfson, Cosby A. Stone, Matthew S. Krantz, Derek K. Chu, Ben A. Dwamena
Summary: This study evaluated immediate allergic reactions caused by mRNA COVID-19 vaccines and assessed the accuracy of skin testing in predicting allergic reactions upon re-vaccination. The results showed that skin testing had low sensitivity but high specificity in predicting repeat allergic reactions. This suggests that skin testing may not be completely accurate in identifying all possible allergic reactions, but it can help exclude the majority of allergic risks.