Article
Infectious Diseases
Youri Yordanov, Aurelien Dinh, Alexandre Bleibtreu, Arthur Mensch, Francois-Xavier Lescure, Erwan Debuc, Patrick Jourdain, Luc Jaulmes, Agnes Dechartres
Summary: This study found that clinical worsening among COVID-19 outpatients is rare, with factors such as male sex, older age, obesity, and comorbidities like chronic renal disease or active cancer independently associated with clinical worsening. However, loss of smell or taste may reduce the probability of worsening.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Obstetrics & Gynecology
Chelsea A. DeBolt, Angela Bianco, Meghana A. Limaye, Jenna Silverstein, Christina A. Penfield, Ashley S. Roman, Henri M. Rosenberg, Lauren Ferrara, Calvin Lambert, Rasha Khoury, Peter S. Bernstein, Julia Burd, Vincenzo Berghella, Elianna Kaplowitz, Jessica R. Overbey, Joanne Stone
Summary: Pregnant women with severe and critical COVID-19 are at an increased risk for certain morbidities when compared with nonpregnant women. Despite higher comorbidities in the nonpregnant group, pregnant women had a higher risk for composite morbidity, intubation, mechanical ventilation, and ICU admission. This suggests that pregnancy may be associated with worse outcomes in women with severe and critical COVID-19.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Pathology
Justin E. Johnson, Declan McGuone, Mina L. Xu, Dan Jane-Wit, Richard N. Mitchell, Peter Libby, Jordan S. Pober
Summary: Severe COVID-19 patients showed frequent and extensive thrombosis in the heart along with signs of neutrophil activation within myocardial thrombi. This suggests that alterations in circulating neutrophils may contribute to the increased thrombotic diathesis in the hearts of COVID-19 patients.
AMERICAN JOURNAL OF PATHOLOGY
(2022)
Article
Health Care Sciences & Services
Jasvinder A. Singh, David B. Nelson, Kristin L. Nichol
Summary: Changes in the mental health component were weakly associated with mortality outcomes, but not significantly correlated with hospitalization. Patient's current HRQOL generally provides meaningful information for predicting subsequent mortality and hospitalization.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2021)
Article
Critical Care Medicine
Matthew P. Kirschen, Nancy McGowan, Alexis Topjian
Summary: It is important to take precautions to avoid viral transmission and ensure patient safety during the evaluation for death by neurologic criteria in patients with suspected or confirmed coronavirus disease 2019.
PEDIATRIC CRITICAL CARE MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
B. M. J. Lampl, M. Lang, C. Jochem, M. F. Leitzmann, B. Salzberger
Summary: In this study conducted in Germany, it was found that COVID-19-related deaths primarily occurred in elderly patients. Deaths attributed to COVID-19 were associated with respiratory symptoms/pneumonia at the time of diagnosis and hospitalizations due to COVID-19. Therefore, the interpretation of COVID-19 death figures needs to be cautious, and more uniform criteria for attributing cause of death among COVID-19 cases are needed.
Article
Neurosciences
Muni Rubens, Anshul Saxena, Venkataraghavan Ramamoorthy, Md Ashfaq Ahmed, Zhenwei Zhang, Peter McGranaghan, Emir Veledar, Michael McDermott, Felipe De Los Rios La Rosa
Summary: COVID-19 hospitalizations are associated with a low risk of acute ischemic stroke (AIS), but it is linked to higher mortality rates and greater rates of discharge to destinations other than home.
Article
Gastroenterology & Hepatology
Millie D. Long, Lauren Parlett, James D. Lewis, Kevin Haynes, Sruthi Adimadhyam, Laura Hou, Audrey Wolfe, Sengwee Toh, Jessica Burris, Jennifer Dorand, Michael D. Kappelman
Summary: This study evaluated the risk of COVID-19 complications in patients with inflammatory bowel disease (IBD) based on their medication usage. The results showed that patients on corticosteroids had higher hospitalization and mechanical ventilation rates, while those on anti-tumor necrosis factor alpha therapy had a lower risk of hospitalization.
INFLAMMATORY BOWEL DISEASES
(2023)
Review
Allergy
Elissa M. Abrams
Summary: Asthma in children appears to be more beneficial than detrimental during COVID-19. There is no evidence to suggest that asthma is a risk factor for more severe outcomes, and there is some basis to suggest that children with atopic asthma may actually have a reduced risk of asthma exacerbations during COVID-19.
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Long Feng, Shihui Fu, Pei Zhang, Yao Yao, Zeguo Feng, Yali Zhao, Leiming Luo
Summary: This review provides an overview of the epidemiology and pathogenesis of COVID-19, and discusses various recommendations for anesthesiologists to minimize the risk of infection when managing patients with severe illness.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Megan G. Hofmeister, Jian Xing, Monique A. Foster, Ryan J. Augustine, Cole Burkholder, Jim Collins, Shannon McBee, Erica D. Thomasson, Douglas Thoroughman, Mark K. Weng, Philip R. Spradling
Summary: During the hepatitis A outbreaks in the United States between 2016 and 2020, factors such as diabetes, cardiovascular disease, and various liver diseases were found to be significantly associated with mortality. Our findings support the Advisory Committee on Immunization Practices' recommendation to vaccinate individuals with chronic liver disease, and suggest consideration of including adults with diabetes and cardiovascular disease in future recommendations.
Article
Critical Care Medicine
Anurag Verma, Jessica Minnier, Emily S. Wan, Jennifer E. Huffman, Lina Gao, Jacob Joseph, Yuk-Lam Ho, Wen-Chih Wu, Kelly Cho, Bryan R. Gorman, Nallakkandi Rajeevan, Saiju Pyarajan, Helene Garcon, James B. Meigs, Yan V. Sun, Peter D. Reaven, John E. McGeary, Ayako Suzuki, Joel Gelernter, Julie A. Lynch, Jeffrey M. Petersen, Seyedeh Maryam Zekavat, Pradeep Natarajan, Sharvari Dalal, Darshana N. Jhala, Mehrdad Arjomandi, Elise Gatsby, Kristine E. Lynch, Robert A. Bonomo, Matthew Freiberg, Gita A. Pathak, Jin J. Zhou, Curtis J. Donskey, Ravi K. Madduri, Quinn S. Wells, Rose D. L. Huang, Renato Polimanti, Kyong-Mi Chang, Katherine P. Liao, Philip S. Tsao, Peter W. F. Wilson, Adriana M. Hung, Christopher J. O'Donnell, John M. Gaziano, Richard L. Hauger, Sudha K. Iyengar, Shiuh-Wen Luoh
Summary: The MUC5B gene polymorphism rs35705950-T is associated with reduced risk of hospitalization and post-COVID-19 pneumonia in individuals of European ancestry, according to a study involving participants in the Million Veteran Program (MVP).
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Endocrinology & Metabolism
Sonja Stojanovic, Bojana Stamenkovic, Jovan Nedovic, Ivana Aleksic, Jelena Jovanovic, Jovana Cvetkovic, Jasmina Jocic, Miljana Sarac, Novica Dimic, Marija Andjelkovic Apostolovic, Milovan Stojanovic
Summary: This study analyzed the impact of disease-modifying antirheumatic drugs, vaccination status, and clinical and demographic characteristics on the hospitalization rate of COVID-19 patients with rheumatoid arthritis. The results showed that treatment with disease-modifying antirheumatic drugs, except for rituximab, did not increase the risk of hospitalization, while the use of tocilizumab proved to be protective. Age, hypertension, and rituximab therapy were identified as independent factors associated with the hospitalization of rheumatoid arthritis patients.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Article
Environmental Sciences
Zahra Moulana, Mojgan Bagherzadeh, Mohammad Mirzakhani, Ali Rostami, Mousa Mohammadnia-Afrouzi, Mehdi Shahbazi
Summary: The study found an association between PTX3 levels and disease severity in COVID-19 patients, while ficolin may not play a crucial role in the severity of the disease.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Infectious Diseases
Ivan De Jesus Ascencio-Montiel, Oscar David Ovalle-Luna, Ramon Alberto Rascon-Pacheco, Victor Hugo Borja-Aburto, Gerardo Chowell
Summary: This report analyzed the epidemiological patterns of COVID-19 cases in the Mexican Institute of Social Security, the largest healthcare provider in Mexico. The study found an increase in case numbers and a decrease in severity metrics across five pandemic waves. The highest hospital case fatality rate was observed during the second wave in winter 2020, and there was a notable decrease in hospitalization among individuals aged 60 years and older. The risk of severe disease and death was positively associated with comorbidities, age, and male gender, and declined with later waves and vaccination status.
BMC INFECTIOUS DISEASES
(2022)
