Article
Obstetrics & Gynecology
Brisandy Ruiz Mercedes, Ayna Serwat, Lena Naffaa, Nairovi Ramirez, Fatima Khalid, Sofia B. Steward, Omar Gabriel Caro Feliz, Mohamad Bassam Kassab, Lina Karout
Summary: This study retrospectively reviewed the clinical data of 15 pregnant women with coronavirus disease 2019 and myocardial injury in a tertiary care hospital in the Dominican Republic. It found a 13.3% mortality rate in these patients, primarily attributed to malignant arrhythmias.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Medicine, General & Internal
Lin-Ming Zhang, Huan-Bo Zhang, Fu-Rong Fan, Ming-Wei Liu
Summary: This article reports a case of spinal cord hematoma in a patient with COVID-19, which has never been reported before. The patient's symptoms significantly improved after treatment and was discharged from the hospital. COVID-19 can not only lead to brain injury but also cause spinal cord injury and hemorrhage.
Article
Medicine, General & Internal
Victor Arevalos, Luis Ortega-Paz, Juan Jose Rodriguez-Arias, Margarita Calvo, Leticia Castrillo, Anthony Salazar, Merce Roque, Ana Paula Dantas, Manel Sabate, Salvatore Brugaletta
Summary: The exact mechanisms of myocardial injury in COVID-19 are still unknown. This study found that myocardial injury in COVID-19 patients is associated with inflammation and coagulopathy, leading to a worse in-hospital prognosis. Treatment with anticoagulant agents may help improve in-hospital outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Marie E. Thoma, Eugene R. Declercq
Summary: This study found that pregnancy-related mortality ratios increased significantly in 2021 compared to 2020, which is consistent with the rising rates of COVID-19-associated mortality among women of reproductive age. The increase was particularly pronounced among American Indian/Alaska Native birthing people.
OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Michael Richley, Rashmi R. Rao, Yalda Afshar, Jenny Mei, Thalia Mok, Tara Vijayan, Stacey Weinstein, Christine U. Pham, Jason Madamba, Christina S. Shin, Deborah Suda, Christina S. Han
Summary: This study presents a retrospective case series of pregnant patients who received monoclonal antibody treatment for COVID-19, and the results suggest that pregnant patients who received treatment generally had favorable outcomes.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Virology
Jian Wang, Li Zhu, Leyang Xue, Longgen Liu, Xuebing Yan, Xiaomin Yan, Songping Huang, Biao Zhang, Tianmin Xu, Chunyang Li, Fang Ji, Fang Ming, Yun Zhao, Juan Cheng, Huaping Shao, Kang Chen, Xiang-an Zhao, Dawen Sang, Haiyan Zhao, Xinying Guan, Xiaobing Chen, Yuxin Chen, Jiacheng Liu, Rui Huang, Chuanwu Zhu, Chao Wu
Summary: Mild to moderate liver injury was common in COVID-19 patients in Jiangsu, China. Age over 50 years, male sex, and lopinavir-ritonavir were identified as independent risk factors for liver impairment during hospitalization.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Endocrinology & Metabolism
Yutian Tian, Junyu Zhao, Tingting Wang, Haipeng Wang, Jinming Yao, Song Wang, Yaru Mou
Summary: This study used a meta-analysis to investigate the impact of thyroid disease on the severity of COVID-19 infection. The findings showed that COVID-19 patients with thyroid diseases, particularly in Asia, are more likely to develop severe conditions. The study also found an association between severe COVID-19 infection and complications such as hypothyroidism and low T3 syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Mariha Khan, Samhita Bhattarai, Thomas G. Boyce, Reyaad A. Hayek, Sergey Zhadanov, Elisabeth E. Hooper, Edward G. Fernandez, Monica A. Koehn
Summary: A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with severe acute respiratory syndrome coronavirus 2 based on clinical presentation, neuroimaging, and cerebrospinal fluid studies. The patient received high-dose intravenous methylprednisolone, tocilizumab, and intravenous immunoglobulin treatment, which resulted in significant short-term clinical improvement but long-term sequelae.
JOURNAL OF PEDIATRICS
(2022)
Article
Cardiac & Cardiovascular Systems
Chongtu Yang, Fen Liu, Wei Liu, Guijuan Cao, Jiacheng Liu, Songjiang Huang, Muxin Zhu, Chao Tu, Jianwen Wang, Bin Xiong
Summary: Patients with COVID-19 pneumonia may experience myocardial injury, with elevated levels of d-dimer, CK-MB, Troponin I, and CRP serving as risk factors for short-term mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Youseung Chung, Eun Jin Kim, Hee-Sung Kim, Kyung-Hwa Park, Ji Hyeon Baek, Jungok Kim, Ji Yeon Lee, Chang-Seop Lee, Seungjin Lim, Shin-Woo Kim, Eu Suk Kim, Hye Jin Shi, Shin Hee Hong, Jae-Bum Jun, Kyung-Wook Hong, Jae-Phil Choi, Jinyeong Kim, Kyung Sook Yang, Young Kyung Yoon
Summary: This study describes the outcomes of pregnant women, obstetrics, and neonates with COVID-19 and identifies predictors of disease severity. The gestational age at COVID-19 diagnosis and parity were identified as significant risk factors for severe diseases. Vertical transmission of COVID-19 was not observed, and maternal severity did not significantly affect the neonatal prognosis.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2022)
Article
Cardiac & Cardiovascular Systems
Huiqi Guo, Yunzhi Shen, Ning Wu, Xiaotian Sun
Summary: The study found that myocardial injury in severe and critical COVID-19 patients led to poor prognosis, including increased duration of mechanical ventilation, incidence of malignant arrhythmia, and mortality.
JOURNAL OF CARDIAC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Michael Briscoe, Robert Sykes, Thomas Krystofiak, Oliver Peck, Kenneth Mangion, Colin Berry
Summary: The clinical significance of COVID-19 as a factor in myocardial injury is controversial. This study found that COVID-19 patients with myocardial injury often exhibit non-cardiac myocardial injury/Type 2 MI, have fewer comorbidities, longer hospital stays, and higher in-hospital mortality rates. These findings suggest a complex relationship between COVID-19, myocardial injury, and patient outcomes.
CLINICAL CARDIOLOGY
(2021)
Article
Immunology
Jian He, Bicheng Zhang, Quan Zhou, Wenjing Yang, Jing Xu, Tingting Liu, Haijun Zhang, Zhiyong Wu, Dong Li, Qing Zhou, Jie Yan, Cuizhen Zhang, Haiyan Qian, Minjie Lu, Xiaoyang Zhou
Summary: This study included 304 hospitalized COVID-19 patients and found that patients with myocardial injury have more comorbidities and severe condition. Myocardial injury and high Hs-TnI are the strongest independent predictors of mortality in COVID-19 patients.
IMMUNITY INFLAMMATION AND DISEASE
(2021)
Article
Virology
Timotius Ivan Hariyanto, Andree Kurniawan
Summary: Meta-analysis study suggests that tocilizumab treatment is effective in reducing the biomarkers of COVID-19 infection.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Anesthesiology
Ajay Pillai, Barbara Lawson
Summary: Cardiovascular involvement is common in COVID-19, with manifestations such as venous thromboembolism, atrial fibrillation, and myocardial infarction. Viral myocarditis is rare, but COVID-19 vaccination has been associated with myocarditis and pericarditis. COVID-19-related myocardial injury is associated with mechanical ventilation, hemodynamic deterioration, and increased mortality.
CURRENT OPINION IN ANESTHESIOLOGY
(2022)
Article
Genetics & Heredity
William M. Brandler, Danny Antaki, Madhusudan Gujral, Amina Noor, Gabriel Rosanio, Timothy R. Chapman, Daniel J. Barrera, Guan Ning Lin, Dheeraj Malhotra, Amanda C. Watts, Lawrence C. Wong, Jasper A. Estabillo, Therese E. Gadomski, Oanh Hong, Karin V. Fuentes Fajardo, Abhishek Bhandari, Renius Owen, Michael Baughn, Jeffrey Yuan, Terry Solomon, Alexandra G. Moyzis, Michelle S. Maile, Stephan J. Sanders, Gail E. Reiner, Keith K. Vaux, Charles M. Strom, Kang Zhang, Alysson R. Muotri, Natacha Akshoomoff, Suzanne M. Leal, Karen Pierce, Eric Courchesne, Lilia M. Iakoucheva, Christina Corse, Jonathan Sebat
AMERICAN JOURNAL OF HUMAN GENETICS
(2016)
Article
Pediatrics
Sunnie Yan-Wai Wong, Lesa J. Beamer, Therese Gadomski, Tomas Honzik, Miski Mohamed, Saskia B. Wortmann, Katja S. Brocke Holmefjord, Marit Mork, Francis Bowling, Jolanta Sykut-Cegielska, Dieter Koch, Amanda Ackermann, Charles A. Stanley, Daisy Rymen, Avraham Zeharia, Moeen Al-Sayed, Thomas Marquardt, Jaak Jaeken, Dirk Lefeber, Donald F. Conrad, Tamas Kozicz, Eva Morava
JOURNAL OF PEDIATRICS
(2016)
Article
Genetics & Heredity
Sunnie Yan-Wai Wong, Therese Gadomski, Monique van Scherpenzeel, Tomas Honzik, Hana Hansikova, Katja S. Brocke Holmefjord, Marit Mork, Francis Bowling, Jolanta Sykut-Cegielska, Dieter Koch, Jozef Hertecant, Graeme Preston, Jaak Jaeken, Nicole Peeters, Stefanie Perez, David Do Nguyen, Kea Crivelly, Tim Emmerzaal, K. Michael Gibson, Kimiyo Raymond, Nurulamin Abu Bakar, Francois Foulquier, Gernot Poschet, Amanda M. Ackermann, Miao He, Dirk J. Lefeber, Christian Thiel, Tamas Kozicz, Eva Morava
GENETICS IN MEDICINE
(2017)
Article
Endocrinology & Metabolism
Willy Morelle, Sven Potelle, Peter Witters, Sunnie Wong, Leslie Climer, Vladimir Lupashin, Gert Matthijs, Therese Gadomski, Jaak Jaeken, David Cassiman, Eva Morava, Francois Foulquier
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2017)
Article
Biochemistry & Molecular Biology
Jacob J. Michaelson, Yujian Shi, Madhusudan Gujral, Hancheng Zheng, Dheeraj Malhotra, Xin Jin, Minghan Jian, Guangming Liu, Douglas Greer, Abhishek Bhandari, Wenting Wu, Roser Corominas, Aine Peoples, Amnon Koren, Athurva Gore, Shuli Kang, Guan Ning Lin, Jasper Estabillo, Therese Gadomski, Balvindar Singh, Kun Zhang, Natacha Akshoomoff, Christina Corsello, Steven McCarroll, Lilia M. Iakoucheva, Yingrui Li, Jun Wang, Jonathan Sebat
Article
Endocrinology & Metabolism
Kyle Scott, Therese Gadomski, Tamas Kozicz, Eva Morava
JOURNAL OF INHERITED METABOLIC DISEASE
(2014)
Article
Medicine, General & Internal
Eran Bornstein, Gregg Husk, Erez Lenchner, Amos Grunebaum, Therese Gadomski, Cristina Zottola, Sarah Werner, Jamie S. Hirsch, Frank A. Chervenak
Summary: Transitioning to a standardized multimodal combination analgesic therapy after cesarean delivery significantly reduces opioid use, decreases average opioid dose, increases acetaminophen dose, and improves pain control. This approach can be effectively implemented on a large scale through incorporation of a multimodal order set in the electronic medical record system.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Genetics & Heredity
Therese E. Gadomski, Melody Bolton, Majid Alfadhel, Chris Dvorak, Olalekan A. Ogunsakin, Stephen L. Nelson, Eva Morava
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
(2017)