Article
Chemistry, Analytical
Jayoung Kim, Byeong-Seok Moon, Eunhee Hwang, Samy Shaban, Wonjung Lee, Do-Gi Pyun, Dong Hyun Lee, Dong-Hwan Kim
Summary: Researchers have developed a highly sensitive solid-state biosensor based on PDA liposomes, which can enhance sensitivity without relying on labels by adding gold nanoparticles (AuNPs) on the PDA liposomes.
Article
Chemistry, Multidisciplinary
Ryunhyung Kim, Byeonggeol Mun, Seongjae Lim, Chaewon Park, Jinyoung Kim, Jaewook Lim, Hyein Jeong, Hye Young Son, Hyun Wook Rho, Eun-Kyung Lim, Seungjoo Haam
Summary: A colorimetric sensor based on polydiacetylene is developed for the detection of HER2-overexpressing breast cancer. The sensor offers potential applications in low- and middle-income countries for rapid and affordable diagnosis of HER2-overexpressing breast cancer.
Article
Polymer Science
Riccardo Sergi, Benedetta Brugnoli, Elisa Sturabotti, Antonella Piozzi, Luciano Galantini, Vincenzo Taresco, Iolanda Francolini
Summary: This study investigates the blue-to-red phase transition of two polydiacetylenes (PDAs) upon thermal stimulus and α-CD interaction, aiming to develop a colorimetric sensor for food phenolic antioxidants. The change in the PDA polar head does not significantly affect the thermal-chromatic transition, while the PDA/α-CD interaction is influenced by intermolecular forces among PDA polar heads, with a stronger effect on PCDA. The PCDA/α-CD assemblies are explored as colorimetric sensors for the detection of Tyrosol (Ty) and caffeic acid (CAF), with higher sensitivity towards CAF.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2023)
Review
Chemistry, Multidisciplinary
Bratati Das, Seiko Jo, Jianlu Zheng, Jiali Chen, Kaori Sugihara
Summary: This mini review summarizes recent progress in PDA mechanochromism, with a special focus on the quantitative and nanoscopic data that have emerged in recent years.
Article
Chemistry, Applied
Soojin Jang, Seong Uk Son, Junseok Kim, Hyungjun Kim, Jaewoo Lim, Seung Beom Seo, Byunghoon Kang, Taejoon Kang, Juyeon Jung, Sungbaek Seo, Eun-Kyung Lim
Summary: A colorimetric sensor using PDA-based hydrogel beads has been developed to conveniently detect food spoilage. The sensor can visually confirm the presence of biogenic amines through color changes, providing an efficient and accurate method.
Article
Chemistry, Multidisciplinary
Charlotte N. Elliott, Maria Cecilia Becerra, J. Craig Bennett, Lori Graham, M. C. Jazmin Silvero, Geniece L. Hallett-Tapley
Summary: This study successfully synthesized gold nanoparticles and conjugated them with antibiotics for rapid detection of pathogenic bacteria. The results indicate that ATB@AuNP encapsulates antibiotic molecules on the nanoparticle surface, providing efficient and high throughput detection capability for common bacteria.
Article
Materials Science, Multidisciplinary
Papaorn Siribunbandal, Tanakorn Osotchan, Yong-Hoon Kim, Rawat Jaisutti
Summary: This study presents a simple-to-use colorimetric sensor that can detect gases released from food spoilage, making it highly relevant for food safety, shelf-life indicators, and food waste management. By optimizing the weight ratio of zinc oxide nanopellets in the composite film, a high colorimetric response of about 51.5% was achieved for 200 ppm ammonia gas exposure, which can be observed by the naked eye. The embedded polydimethylsiloxane film sensors showed thermal and storage stability, as well as excellent selectivity for ammonia gas compared to other volatile organic compounds. The sensors were used to assess the degree of spoilage in chicken and pork meat under different storage conditions, indicating their potential application as colorimetric sensors for meat freshness indicators in smart food packaging.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Physical
Watsapon Yimkaew, Rakchart Traiphol, Nisanart Traiphol
Summary: This study explores the application of colorimetric sensors based on polydiacetylene (PDA)/Zn2+/ZnO nanocomposites for detecting organic acid-base in various organic solvents and food products. The sensitivity of the sensors varies with the solvent properties, and it can be fine-tuned by adjusting the ratios of ZnO within the nanocomposites. The solid-state sensors embedded in nylon filters can determine the concentration of sorbic acid in fruit juices and indicate the freshness of milk through naked-eye detection.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Rungarune Saymung, Anyarat Watthanaphanit, Nagahiro Saito, Nisanart Traiphol, Rakchart Traiphol
Summary: A new route for synthesizing polydiacetylene (PDA) is introduced by generating plasma in a liquid matrix and using the products as initiators for polymerization. The resulting PDA materials exhibit thermochromic properties and can be fabricated into colorimetric sensors. This synthetic pathway has potential industrial-scale applications.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Chemistry, Analytical
Jalal N. Jeber, Raed F. Hassan, Mohammad K. Hammood, Oday H. R. Al-Jeilawi
Summary: Two simple, accurate, precise, and economical colorimetric methods have been developed for the visual detection and quantitative determination of SEM in commercial flour products. These methods can detect SEM by bare eye observation at very low concentrations and can also be used for quantitative determination using a spectrophotometer.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Applied
Poorti Mohindroo, Jayrajsinh Sarvaiya, Sonal Dange, K. Sushma Varma
Summary: Liposome sensors conjugated with polydiacetylene (PDA) have been developed for on-site quantification of aflatoxin from feed samples with the assistance of a mobile phone-based application. The soyabean-sourced phosphatidylcholine served as a stronger and cheaper alternative backbone for the lipoid sensor, providing consistent chromatic response with aflatoxin. These sensors can detect the presence of aflatoxin in food and animal feed matrices within 5 minutes, with a reliable detection limit of 5.7 ppb.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Yun Kyung Jung, Min Hyeong Son
Summary: Exosomes serve important biological functions in intercellular communication and transportation of biomolecules. Malignant exosomes have gained attention as potential indicators for cancer detection and treatment. Our PDA-based aptasensors show great potential for on-site cancer diagnosis by swiftly and accurately identifying malignant exosomes.
Article
Environmental Sciences
Chatthai Kaewtong, Banchob Wanno, Wandee Rakrai, Audchara Saenkham, Sanguansak Sriphalang, Datchanee Pattavarakorn, Thawatchai Tuntulani, Buncha Pulpoka
Summary: Researchers have developed a colorimetric chemosensor array platform of polydiacetylene combined with rhodamine B, which can be used for sensitive detection of Au3+ ions in environmental and biological applications, showing high sensitivity and selectivity.
ENVIRONMENTAL TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Aphiwat Pankaew, Jirapa Rueangsuwan, Rakchart Traiphol, Nisanart Traiphol
Summary: This study presents a simple method for fabricating colorimetric sensors that can differentiate the concentration and molecular weight of PMMA. The sensitivity of the sensors can be adjusted by experimental parameters.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Review
Engineering, Chemical
Chantal T. Tracey, Anastasia Kryuchkova, Takshma K. Bhatt, Pavel Krivoshapkin, Elena F. Krivoshapkina
Summary: In order to reduce food waste, the use of biodegradable silk-based coatings and packaging with antimicrobial properties has been proposed to prolong the freshness of fruits and vegetables.
JOURNAL OF FOOD ENGINEERING
(2023)
Article
Engineering, Chemical
William J. Sawyer, A. John Hart
Summary: The size and composition of nanoparticles are crucial for catalytic processes. This study focuses on the controlled synthesis of sub-3 nm iron nanoparticle aerosols and the mechanisms behind their growth. By using a custom-built atmospheric pressure DC microplasma reactor, the researchers were able to achieve precise diameter control and high yield of the nanoparticles. A charge-mediated formation mechanism was proposed to explain the growth process, although it couldn't fully explain the observed rapid growth rate. This research is important for optimizing nanoparticle yield, throughput, and diameter control.
JOURNAL OF AEROSOL SCIENCE
(2022)
Article
Engineering, Industrial
Ali Gokhan Demir, Jinwoo Kim, Fabio Caltanissetta, A. John Hart, C. Cem Tasan, Barbara Previtali, Bianca Maria Colosimo
Summary: This study demonstrates the use of LPBF to achieve gradient structures by mixing two austenitic steels and controlling the chemical compositions and mechanical properties along the build direction.
JOURNAL OF MATERIALS PROCESSING TECHNOLOGY
(2022)
Article
Mechanics
Crystal E. E. Owens, Max R. R. Fan, A. John Hart, Gareth H. H. McKinley
Summary: This article introduces the study of Oreology, which focuses on the flow and fracture of sandwich cookies, using the example of the iconic Oreo cookie. The authors use a laboratory rheometer to measure the failure mechanics of the Oreo's creme and investigate the impact of rotation rate, creme amount, and flavor on the stress-strain curve and creme distribution. The results show adhesive failure under normal conditions, with the majority of the creme remaining on one wafer, but cohesive failure under adverse conditions, resulting in the creme dividing between wafer halves.
Article
Chemistry, Multidisciplinary
Muchun Liu, Pierre-Eric Millard, Henning Urch, Ophelie Zeyons, Douglas Findley, Rupert Konradi, Benedetto Marelli
Summary: There is a growing demand for biodegradable alternatives to non-degradable microplastics in various industries. In this study, the authors demonstrate the microencapsulation of active substances in silk fibroin by adjusting the protein's protonation and chain relaxation. The size of the silk fibroin micelles can be tuned, enabling the manufacturing of microcapsules with various morphologies and structures. The degradation kinetics and sustained release of soluble and insoluble payloads are controlled by modulating the fibroin's beta-sheet content. The microencapsulation of a commonly used herbicide in silk fibroin significantly reduces its burst release, and a greenhouse trial shows reduced crop injury compared to the non-encapsulated version.
Article
Chemistry, Multidisciplinary
Augustine T. Zvinavashe, Zeina Barghouti, Yunteng Cao, Hui Sun, Doyoon Kim, Muchun Liu, Eugene J. Lim, Benedetto Marelli
Summary: There is an urgent need to find new materials for use in the food, water, and agriculture industries that are biodegradable, have a sustainable life cycle, and are sourced at scale. In this study, the degradation of regenerated silk fibroin (SF) in different soil and water environments is investigated. The research shows that the degradation of SF is influenced by factors such as SF polymorphism, ionic strength, and the presence of microorganisms. It is found that microbial activity is a key driver for the degradation of silk and that the degradation rate can be controlled through material design and regulation of the interaction with environmental microorganisms.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Yunteng Cao, Sally Shuxian Koh, Yangyang Han, Javier Jingheng Tan, Doyoon Kim, Nam-Hai Chua, Daisuke Urano, Benedetto Marelli
Summary: New systems for agrochemical delivery in plants, such as silk-based microneedles, have been shown to effectively deliver bioactive molecules and stimulate growth and development in various crop species. These methods have the potential to revolutionize agricultural practices and provide valuable tools for plant science research.
ADVANCED MATERIALS
(2023)
Article
Engineering, Mechanical
Kaitlyn Gee, Suh In Kim, Haden Quinlan, A. John Hart
Summary: This study presents a framework to estimate the throughput and cost of additive manufacturing (AM). The framework takes into account process parameters, material thermodynamic properties, and machine specifications. The study also analyzes the tradeoff between production cost and machine capability, providing insights beyond the limits of current commercially available equipment.
RAPID PROTOTYPING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Yangyang Han, Song Wang, Yunteng Cao, Gajendra Pratap Singh, Suh In Loh, Raju Cheerlavancha, Mervin Chun-Yi Ang, Duc Thinh Khong, Patrina Wei Lin Chua, Peiying Ho, Michael S. Strano, Benedetto Marelli
Summary: To tackle the challenges in tropical AgriFood systems, we have designed biodegradable packaging materials that can detect spoilage and prevent mold growth. By integrating covalent organic frameworks with silk fibroin, we obtained biodegradable membranes with enhanced mechanical properties and immediate colorimetric response to spoilage. Additionally, loading antimicrobial hexanal into the frameworks reduced biotic spoilage and mold growth in soybeans by four orders of magnitude compared to cling film. This integration of sensing, reinforcement, and antimicrobial agent delivery defines climate-specific packaging materials that can reduce food waste and improve food safety.
Article
Engineering, Environmental
Yilin Zhang, Michael R. Martinez, Hui Sun, Mingkang Sun, Rongguan Yin, Jiajun Yan, Benedetto Marelli, Juan Pablo Giraldo, Krzysztof Matyjaszewski, Robert D. Tilton, Gregory V. Lowry
Summary: The understanding of how agrochemical nanocarrier properties affect their uptake and translocation in plants is incomplete. Our study found that anionic nanocarriers were transported at a higher rate than cationic nanocarriers in tomato, while only anionic nanocarriers were transported in wheat. These findings provide design parameters for efficient and targeted agrochemical delivery.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Hui Sun, Benedetto Marelli
Summary: Nanotubular structures made of silk proteins are fabricated using a template wetting approach with multiple silk-based suspensions. Precise control over the size, density, aspect ratio, and morphology of silk nanostructures allows for programmable modulation of the end materials' functions and properties. The silk nanotube arrays show great utility as antifouling coatings and in oil extraction from oil-water mixtures.
Article
Chemistry, Multidisciplinary
Yilin Zhang, Liye Fu, Michael R. Martinez, Hui Sun, Valeria Nava, Jiajun Yan, Kurt Ristroph, Saadyah E. Averick, Benedetto Marelli, Juan Pablo Giraldo, Krzysztof Matyjaszewski, Robert D. Tilton, Gregory V. Lowry
Summary: Anticipated increases in extreme temperatures can harm crops, but the use of high aspect ratio polymer bottlebrushes can mitigate these effects by delivering stress-regulating agents to plants. These bottlebrushes have shown efficient uptake in leaves and can release encapsulated agents under elevated temperatures, promoting photosynthesis and providing long-term heat stress protection. They can also move through the phloem to protect other plant organs and manage phloem pathogens, making this delivery platform a valuable tool for protecting plants against climate-induced damage.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Hui Sun, Saurav Maji, Anantha P. Chandrakasan, Benedetto Marelli
Summary: Smallholder farmers and manufacturers in the Agri-Food sector face challenges due to the increasing circulation of counterfeit products. Current countermeasures are vulnerable and implemented mainly at the secondary packaging level. This study proposes a cryptographic protocol for seed authentication using biodegradable and miniaturized PUF tags made of silk microparticles.
Article
Nanoscience & Nanotechnology
Dhanushkodi D. Mariappan, Sanha Kim, Junjie Zhao, Hangbo Zhao, Ulrich Muecke, Karen Gleason, Akintunde Ibitayo Akinwande, A. John Hart
Summary: To achieve high-performance printed electronic devices, scalable and cost-effective printing of high-quality metallic electrodes with narrow gaps is desirable. This study demonstrates short channel transistors (<10 μm) with thin electrodes (<100-200 nm) fabricated by flexographic printing with nanoporous stamps, using single-wall carbon nanotubes as the network semiconductor. The measured performance of these transistors meets or exceeds those of previously reported SWCNT network transistors fabricated by alternative printing methods.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yue Hu, Federica Rigoldi, Hui Sun, Alfonso Gautieri, Benedetto Marelli
Summary: We used molecular dynamics simulations to find new tetrapeptide sequences with pH-tunable assembly properties by screening all possible histidine-bearing sequences. These tetrapeptides have potential applications in triggering the delivery of bioactive molecules.
CHEMICAL COMMUNICATIONS
(2023)