Article
Materials Science, Multidisciplinary
Muhammad Talal Ali Khan, Haisu Li, Nathan Nam Minh Duong, Andrea Blanco-Redondo, Shaghik Atakaramians
Summary: The study presents a new method to enhance integrated terahertz systems performance utilizing topological photonic crystals, demonstrated by experimental validation of topological terahertz planar air-channel metallic waveguides. This technology, combining 3D printing and gold sputtering, shows significant performance improvements and robust transmission characteristics.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Materials Science, Multidisciplinary
Jun Feng, Yijun Zheng, Qiyang Jiang, Malgorzata K. Wlodarczyk-Biegun, Samuel Pearson, Aranzazu del Campo
Summary: This paper presents an extrusion printing method for manufacturing flexible optical waveguides, and demonstrates the performance of the printed fibers in terms of optical loss, Young's Modulus, and stretchability. This method simplifies the fabrication process of compliant and stretchable devices from materials approved for clinical use.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Engineering, Biomedical
Yucheng Mei, Chengzu He, Chunxia Gao, Peizhi Zhu, Guanming Lu, Hongmian Li
Summary: The study successfully fabricated porous polylactic acid/methotrexate (PLA/MTX) scaffolds using 3D printing technology as controllable drug delivery devices for tumor growth suppression. The results showed significant inhibitory effects on tumor cells with relatively low toxicity on normal cells and no obvious side effects on organs.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2021)
Article
Dentistry, Oral Surgery & Medicine
P-C Chang, Z-J Lin, H-T Luo, C-C Tu, W-C Tai, C-H Chang, Y-C Chang
Summary: Recent research has focused on developing scaffolds with intricate configurations and manipulating extracellular matrix stiffness towards osteogenesis for maxillofacial defect regeneration. The study proposed infusing a degradable RGD-functionalized alginate matrix (RAM) with osteoid-like stiffness into a rigid 3D-printed hydroxyapatite scaffold. In vitro and in vivo results showed that RAM with osteoid-like stiffness, particularly when oxidized, significantly enhanced bone marrow stem cell viability, migration, and osteogenic differentiation, ultimately promoting robust bone formation in maxillofacial regeneration.
JOURNAL OF DENTAL RESEARCH
(2021)
Article
Materials Science, Composites
Binbin Guo, Yukun Zhong, Xiaoteng Chen, Shixiang Yu, Jiaming Bai
Summary: Electrically conductive hydrogels have been widely used in flexible wearable strain sensors due to their superior electrical conductivity, stretchability, and biocompatibility. However, modifying conductive fillers and the non-degradability of traditional hydrogels have been challenging issues. In this study, a digitally 3D printed electrically conductive and degradable hydrogel was developed, alleviating the complexity of preparation and addressing environmental pollution caused by electronic waste.
COMPOSITES COMMUNICATIONS
(2023)
Article
Engineering, Biomedical
Yu Hu, Hao Tang, Nan Xu, Xiaowo Kang, Weijun Wu, Chuhan Shen, Junsheng Lin, Yinyin Bao, Xingyu Jiang, Zhi Luo
Summary: This study introduces a novel 3D printable wound dressing that is composed of three commonly used non-toxic compounds. The material exhibits tunable degradation kinetics and high flexibility, making it a promising option for personalized wound care.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Medicine, Research & Experimental
Paromita Sarbadhikary, Blassan P. George, Heidi Abrahamse
Summary: Advancements in biophotonics have revolutionized the fields of biomedical science and engineering, providing powerful diagnostic and therapeutic capabilities. Recent innovations in material science, biomedical optics, processing technology, and nanotechnology have enabled sophisticated technologies such as wireless remote-controlled micro devices.
Article
Engineering, Manufacturing
Rolando Salazar, Francisco Pizarro, Dreidy Vasquez, Eva Rajo-Iglesias
Summary: This article evaluates four different 3D-printed rectangular waveguide structures using highly conductive filaments, operating from 8 GHz to 40 GHz. By applying a smoothing treatment based on chloroform, the high-frequency transmission losses are significantly reduced, with a reduction of around 65% achieved in higher frequencies.
ADDITIVE MANUFACTURING
(2022)
Editorial Material
Oncology
Kai Huang, Xiaoxuan Liu, Gang Han, Yubin Zhou
Summary: Chimeric antigen receptor (CAR) T cell-based immunotherapy has shown promising results in cancer treatment, but safety issues and lack of strict antigen specificity still exist. The combination of nanotechnology, optogenetics, and immunoengineering can potentially develop controllable CAR T cells for personalized therapy.
CLINICAL AND TRANSLATIONAL MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Archish Muralidharan, Robert R. McLeod, Stephanie J. Bryant
Summary: PBAE-diacrylate resins offer a wide range of available chemistries and tunable material properties for 3D printing applications. Depending on the chemistry, these resins can exhibit varying degradation behaviors, from bulk degradation to surface degradation, with different degradation rates under accelerated conditions. The high-resolution 3D printed parts achieved through simple chemical modifications in the resins combined with projection microstereolithography have similar architectures and initial properties but diverse degradation behaviors.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Noemie Gil, Constance Thomas, Rana Mhanna, Jessica Mauriello, Romain Maury, Benjamin Leuschel, Jean-Pierre Malval, Jean-Louis Clement, Didier Gigmes, Catherine Lefay, Olivier Soppera, Yohann Guillaneuf
Summary: Researchers have found that by adding dibenzo[c,e]-oxepane-5-thione (DOT) to acrylate-based resins, weak bonds can be introduced into the materials used in 3D printing, making them biodegradable. The small amount of additive does not significantly affect the printability, resolution, and mechanical properties of the resin. The resin with additive can be used in different photolithography setups and degrades in solvents and compost, with the rate of degradation depending on the size of the object. This study opens up new possibilities for creating easily soluble 3D objects.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Acoustics
R. Sailesh, L. Yuvaraj, Jeyaraj Pitchaimani, Mrityunjay Doddamani, Lenin Babu Mailan Chinnapandi
Summary: The research presents the influence of perforations with arbitrarily varying cross-sections on the acoustic behavior of 3D printed bio-degradable panels made of Poly Lactic Acid (PLA). Results show that perforated panels with varying cross-sections exhibit better sound absorption compared to uniform cross-sectional perforations, with DC and D perforation patterns showing comparable and lower transmission losses. Geometrical perforation variations are crucial in designing soundproof panels, as demonstrated in the study, and numerical analysis provides guidelines for designing optimum perforation geometries.
Article
Polymer Science
Sebastian-Marian Zaharia, Mihai Alin Pop, Mihaela Cosnita, Catalin Croitoru, Simona Matei, Cosmin Spirchez
Summary: This study develops and characterizes 3D-printed panels with acoustic properties. The triangular configuration with 40% infill density shows the best acoustic performance and strength.
Article
Materials Science, Multidisciplinary
Yi Zheng, Yangdong Wang, Fan Zhang, Shaomin Zhang, Kiryl D. Piatkevich, Nanjia Zhou, Jonathan K. Pokorski
Summary: PEDOT:PSS is a promising material with broad applications in energy storage, flexible electronics, and bioelectronics. A 3D printing method using a room-temperature coagulation bath-based direct ink writing technique is reported, allowing for high quality parts with stable performance. The mechanical properties of the printed parts can be improved by modifying the coagulation bath.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Materials Science, Multidisciplinary
Yiru Zhang, Lei Chen, Mingzhu Xie, Ziheng Zhan, Dongsheng Yang, Ping Cheng, Huigao Duan, Qi Ge, Zhaolong Wang
Summary: This study proposes a conductive cross-linked hydrogel fabricated by 3D printing technique, which can be completely degraded in alkaline environment within seconds. The hydrogels exhibit excellent flexibility and conductivity, making them suitable for applications in electronic skins, tissue engineering, drug delivery, and wearable devices. The effects of temperature, pH value, and chemical compositions on the performance of the hydrogels are also investigated. The potential applications of the printable hydrogel sensors in programmable flexible electronics and human-machine interface are highlighted.
MATERIALS TODAY PHYSICS
(2022)
Correction
Multidisciplinary Sciences
Ernest Latorre, Sohan Kale, Laura Casares, Manuel Gomez-Gonzalez, Marina Uroz, Leo Valon, Roshna V. Nair, Elena Garreta, Nuria Montserrat, Aranzazu del Campo, Benoit Ladoux, Marino Arroyo, Xavier Trepat
Review
Chemistry, Multidisciplinary
Samuel Pearson, Jun Feng, Aranzazu del Campo
Summary: Photoresponsive biomaterials are transitioning towards clinical translation, with challenges in in vivo photoactivation that can be overcome through light management strategies and innovative technologies like upconversion nanoparticles and optical waveguides. The focus is on driving light into the body and integrating light delivery concepts with photoresponsive targets for medical applications. The potential for further innovation in materials-based light delivery platforms is highlighted to meet the needs of in vivo photoactivation of biomaterials.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Engineering, Biomedical
Roshna Nair, Aleeza Farrukh, Aranzazu del Campo
Summary: The photoresponsive biomaterials modified with (P)QK offer a promising approach for precise delivery and spatial control of pro-angiogenic factors in supporting regulated vascular growth through light-triggered mechanisms.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Nanoscience & Nanotechnology
Aleixandre Rodrigo-Navarro, Shrikrishnan Sankaran, Matthew J. Dalby, Aranzazu del Campo, Manuel Salmeron-Sanchez
Summary: Engineered living materials consist of living cells and polymeric matrices, allowing for controllable responses and dynamic functions. Microorganisms as the active component in these materials can respond to environmental stimuli and have a wide range of biomedical applications.
NATURE REVIEWS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Shardul Bhusari, Shrikrishnan Sankaran, Aranzazu del Campo
Summary: This study investigates the growth and metabolic activity of bacteria within a hydrogel network. The results show that the mechanical properties of the matrix can control and regulate the behavior and function of the bacteria, providing new insights for the design of engineered living materials.
Article
Materials Science, Multidisciplinary
Jun Feng, Yijun Zheng, Qiyang Jiang, Malgorzata K. Wlodarczyk-Biegun, Samuel Pearson, Aranzazu del Campo
Summary: This paper presents an extrusion printing method for manufacturing flexible optical waveguides, and demonstrates the performance of the printed fibers in terms of optical loss, Young's Modulus, and stretchability. This method simplifies the fabrication process of compliant and stretchable devices from materials approved for clinical use.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Materials Science, Biomaterials
Malgorzata K. Wlodarczyk-Biegun, Maria Villiou, Marcus Koch, Christina Muth, Peixi Wang, Jenna Ott, Aranzazu del Campo
Summary: This study demonstrates the successful fabrication of fibrillar, porous scaffolds that mimic the multilayer, gradient structure of native HTM using melt electrowriting. The scaffold exhibits good mechanical properties and biocompatibility. Primary HTM cells attach and proliferate on the scaffold, providing new insights and solutions for understanding the structure-function relationship of HTM and regenerative medicine.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Materials Science, Biomaterials
Shardul Bhusari, Juhyun Kim, Karen Polizzi, Shrikrishnan Sankaran, Aranzazu del Campo
Summary: Engineered living materials (ELMs) use non-living matrices to contain microorganisms for various capabilities. This study introduces a bilayer thin film hydrogel that supports bacterial growth while preventing leakage. The composition and properties of the layers can be adjusted independently. The versatility of these bilayer bacteria thin-films is attractive for further studies and application-oriented ELMs development.
BIOMATERIALS ADVANCES
(2023)
Article
Materials Science, Biomaterials
Selim Basaran, Sourik Dey, Shardul Bhusari, Shrikrishnan Sankaran, Tobias Kraus
Summary: Engineered living materials (ELMs) combine genetically engineered microorganisms with inorganic nanostructures to create materials that can respond to external stimuli. In this study, thermogenetically engineered microorganisms are combined with plasmonic gold nanorods (AuNR) to create an ELM that is sensitive to near infrared light. The nanocomposite gel formed by combining AuNR and Pluronic-based hydrogel can convert near infrared light into heat, allowing for remote and real-time control of the ELM's function. The photothermal conversion efficiency of the gel is found to be 47%.
BIOMATERIALS ADVANCES
(2023)
Article
Engineering, Biomedical
Federico Colombo, Maria Villiou, Fereydoon Taheri, Leonard Froehlich, Mohammadreza Taale, Viktoria Albert, Qiyang Jiang, Christine Selhuber-Unkel
Summary: Using advanced imaging techniques, the effects of different molecular weights of PEG on rat embryonic fibroblast cells were studied. It was found that cell dry mass decreased and total cell weight fluctuated after exposure to PEG. Cell stiffness decreased significantly after 48 hours, highlighting the importance of maintaining cell density in cellular activities.
ADVANCED NANOBIOMED RESEARCH
(2023)
Article
Materials Science, Biomaterials
Archana K. Yanamandra, Shardul Bhusari, Aranzazu del Campo, Shrikrishnan Sankaran, Bin Qu
Summary: This study investigated the immune response of human peripheral blood mononuclear cells (PBMCs) exposed to a combination of bacteria and hydrogel. Encapsulation of bacteria in hydrogels significantly reduces their immunogenicity. However, stronger immune responses were observed in pro-inflammatory PBMCs with elevated levels of IL-2, highlighting the need to identify recipients prone to undesired immune responses.
BIOMATERIALS ADVANCES
(2023)
Article
Chemistry, Multidisciplinary
Sara Trujillo, Jennifer Kasper, Adrian de Miguel-Jimenez, Britta Abt, Alina Bauer, Joelle Mekontso, Samuel Pearson, Aranzazu del Campo
Summary: This study finds that PEG hydrogels prepared by the methylsulfonyl-thiol reaction are biocompatible and can be used in clinical applications without causing inflammation. The cytocompatibility of these hydrogels is compared with those prepared by the maleimide-thiol reaction, and the results show that the methylsulfonyl-thiol reaction is more compatible with cells.
Article
Chemistry, Multidisciplinary
Sara Trujillo, Jennifer Kasper, Adrian de Miguel-Jimenez, Britta Abt, Alina Bauer, Joelle Mekontso, Samuel Pearson, Aranzazu del Campo
Summary: The cytocompatibility of the in situ cross-linking reaction by methylsulfonyl-thiol chemistry is evaluated, and compared with maleimide-thiol cross-linked PEGs. The results show that methylsulfonyl-thiol chemistry is cytocompatible and does not trigger high pro-inflammatory responses in endothelial cells and monocytes, making it eligible for in vivo testing and potential clinical application in the future.
Article
Chemistry, Multidisciplinary
Yijun Zheng, Mitchell Kim Liong Han, Qiyang Jiang, Bin Li, Jun Feng, Aranzazu del Campo
MATERIALS HORIZONS
(2020)
