Article
Computer Science, Information Systems
Saeed S. Alqahtani, Toufique A. Soomro, Nisar Ahmed Jandan, Ahmed Ali, Muhammad Irfan, Saifur Rahman, Waleed A. Aldhabaan, Abdulrahman Samir Khairallah, Ismail Abuallut
Summary: This study proposed a five-step technique for assessing the impact of retinal blood vessel coherence on segmentation. The proposed technique achieved good performance in processing retinal image, handling uneven illumination and noise issues, performing grayscale conversion, and applying different filtering methods. The method was validated on STARE and DRIVE databases, showing high sensitivity and accuracy.
Article
Psychiatry
Vittal Korann, Abhishek Appaji, Arpitha Jacob, Priyanka Devi, Bhargavi Nagendra, Dona Maria Chako, Ananth Padmanabha, Umesh Thonse, Rose Dawn Bharath, Vijay Kumar, Shivarama Varambally, Ganesan Venkatasubramanian, Shyam Vasudeva Rao, Carroll A. B. Webers, Tos T. J. M. Berendschot, Naren P. Rao
Summary: Recent research has shown a potential link between retinal vascular measures and brain structure in schizophrenia. The study revealed a significant negative correlation between retinal venular diameter and cortical thickness in specific brain regions of schizophrenia patients, suggesting a potential value of retinal venular diameter as a proxy marker for abnormal neurodevelopment in schizophrenia.
ASIAN JOURNAL OF PSYCHIATRY
(2021)
Article
Chemistry, Multidisciplinary
Roziana Ramli, Khairunnisa Hasikin, Mohd Yamani Idna Idris, Noor Khairiah A. Karim, Ainuddin Wahid Abdul Wahab
Summary: This study introduces a feature-based retinal fundus image registration technique that combines retinal vessels and noise characteristics to increase accuracy. The registration method CURVE-SIFT outperformed existing methods significantly, achieving a higher success rate in image pairing.
APPLIED SCIENCES-BASEL
(2021)
Article
Multidisciplinary Sciences
Linus G. Jansen, Payal Shah, Bettina Wabbels, Frank G. Holz, Robert P. Finger, Maximilian W. M. Wintergerst
Summary: The study evaluated the feasibility of upskilling alternative healthcare cadres in smartphone-based fundus imaging (SBFI) and found that with relatively short training, both ophthalmic assistants and ophthalmologists showed improved examination time, usable field-of-view, and image quality. The results suggest that SBFI is highly learnable and can produce comparable results across different healthcare cadres, aiding in the implementation and planning of future SBFI field studies.
SCIENTIFIC REPORTS
(2021)
Article
Mathematics
Muhammad Arsalan, Adnan Haider, Ja Hyung Koo, Kang Ryoung Park
Summary: Retinal blood vessels are important biomarkers for ophthalmic diseases, but the manual analysis of vascular changes is a tedious task. This study proposes a new network model called VSUL-Net, which accurately extracts retinal vasculature from images without the need for complex preprocessing.
Article
Biology
Jianglan Wang, Yong-Jie Li, Kai-Fu Yang
Summary: The paper proposes a simple and efficient method for retinal fundus image enhancement, which divides the input image into three layers and conducts illumination correction, detail enhancement, and denoising at each layer. The method outperforms other related methods and can simultaneously handle tasks of illumination correction, detail enhancement, and noise suppression.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Multidisciplinary Sciences
E. Midena, G. Marchione, S. Di Giorgio, G. Rotondi, E. Longhin, L. Frizziero, E. Pilotto, R. Parrozzani, G. Midena
Summary: UWF fundus imaging can accurately classify major retinal diseases and may be an alternative to ophthalmoscopy, expanding the range of diseases that can be diagnosed through teleophthalmology.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, Research & Experimental
Gengyuan Wang, Meng Li, Zhaoqiang Yun, Zhengyu Duan, Ke Ma, Zhongzhou Luo, Peng Xiao, Jin Yuan
Summary: The study proposed an algorithm based on multiple subdivisions and a learning curve function for accurate analysis of vascular tortuosity, serving as a biomarker for early diagnosis of diseases like diabetes. The algorithm achieved high correlation with clinical grading and showed good prognostic performance against expert predictions in diabetic patients' retinal images.
EXPERIMENTAL BIOLOGY AND MEDICINE
(2021)
Article
Multidisciplinary Sciences
M. Elena Martinez-Perez, Alun D. Hughes, Simon A. McG. Thom, Kim H. Parker, Nicholas W. Witt
Summary: This study explores the possibility of using low-cost handheld retinal imaging devices for automatically extracting quantifiable measures of retinal blood vessels. The optical properties of available handheld devices were compared using a Zeiss model eye with a USAF resolution test chart. The Horus DEC 200 was the only suitable camera, but it exhibited shortcomings in capturing images of human eyes compared to the Canon CR-DGi retinal desktop camera. Potential improvements are discussed to enhance the performance of handheld retinal imaging devices for quantitative retinal microvascular measurements.
ROYAL SOCIETY OPEN SCIENCE
(2023)
Article
Computer Science, Artificial Intelligence
Imane Mehidi, Djamel Eddine Chouaib Belkhiat, Dalel Jabri
Summary: The main purpose of this paper is to analyze the performance of improved FCM algorithms for retinal blood vessel segmentation. The results demonstrate that the FRFCM and DSFCM_N algorithms achieve better results in terms of noise robustness and blood vessel segmentation, while the FRFCM algorithm requires less time.
Article
Computer Science, Information Systems
A. Jayachandran, S. Ratheesh Kumar, T. Sudarson Rama Perumal
Summary: Deep learning is widely used in various sectors to improve performance, including medical image analysis and pattern recognition. Diabetic retinopathy, a common cause of vision loss in diabetic patients, can be diagnosed by accurately segmenting retinal vessels in fundus images. We propose an innovative MDUNet to achieve better vessel segmentation accuracy.
MULTIMEDIA TOOLS AND APPLICATIONS
(2023)
Review
Ophthalmology
Ramachandran Rajalakshmi, Vijayaraghavan Prathiba, Subramanian Arulmalar, Manoharan Usha
Summary: The global burden of diabetes has led to an increase in diabetic retinopathy (DR), emphasizing the importance of lifelong screening for early detection. Colour fundus photography (CFP) is useful for documentation and counselling, while new technologies like smartphone and handheld fundus cameras are gaining popularity for DR screening and management.
Article
Ophthalmology
Paula M. Marinho, Allexya A. A. Marcos, Ana M. C. Branco, Andre C. Romano, Victoria Sakamoto, Mateus L. Matuoka, Nara F. Moraes, Alexandre Roque, Paulo F. G. M. M. Tierno, Paulo R. A. Ferreira, Walid M. Mourad, Paulo Schor, Michel Farah, Richard B. Rosen, Rubens Belfort, Heloisa Moraes Do Nascimento
Summary: The study investigated ocular clinical findings in patients with confirmed COVID-19 infection, finding a similar rate of intraocular lesions regardless of disease severity. Some patients had eye lesions that compromised vision.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2021)
Article
Chemistry, Multidisciplinary
Natalia Nikoloulopoulou, Isidoros Perikos, Ioannis Daramouskas, Christos Makris, Povilas Treigys, Ioannis Hatzilygeroudis
Summary: Automated retina vessel segmentation is of great importance in assisting ophthalmologists to identify various eye diseases. This paper proposes a novel fully convolutional autoencoder for this task, achieving competitive results on the DRIVE and STARE datasets compared to state-of-the-art methods. The proposed model consists of eight layers and demonstrates high accuracy and specificity.
APPLIED SCIENCES-BASEL
(2023)
Article
Clinical Neurology
Nataliya Pyatka, Matthew K. Banks, Neel Fotedar, Sarah J. DeLozier, Michael Morgan, David C. Preston
Summary: Nonmydriatic ocular fundus photography improves patient care in a Neurology resident clinic and helps residents recognize funduscopic findings.
JOURNAL OF NEURO-OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Min Gao, Mirella Telles Salgueiro Barboni, Dora Fix Ventura, Balazs Vince Nagy
Summary: The study examined the impact of cutoff frequencies on dark-adapted and light-adapted ERG components, finding that fixed and variable filters significantly altered light-adapted components. Lower cutoff frequencies resulted in smaller b-wave and OP3 amplitudes, and higher OP2/OP4 amplitudes. A transition range between 68.9 Hz and 83.9 Hz was observed where amplitudes varied.
DOCUMENTA OPHTHALMOLOGICA
(2022)
Article
Food Science & Technology
Akos Nyitrai, Agnes Urbin, Balazs Vince Nagy, Laszlo Sipos
Summary: This study aimed to find the most effective color masking environment through instrumental characterization and sensory tests of different color masking illuminations on chocolate samples.
FOOD QUALITY AND PREFERENCE
(2022)
Article
Multidisciplinary Sciences
Adel Molnar, Mbuotidem Jeremiah Thomas, Attila Fintha, Magdolna Kardos, Dejan Dobi, Andras Tisler, Nora Ledo
Summary: The study examined the distribution and temporal variation of renal biopsy diagnoses in Hungary over 15 years, revealing an increase in biopsy rates and age of patients, as well as an increasing proportion of membranous nephropathies and age-related diseases. The trends underscore the importance of adapting medical focus to demographic changes in the region.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Mechanical
Agnes Urbin, Balazs Vince Nagy, Klara Wenzel
Summary: This paper compares the results of chromatic discrimination measurements obtained in two different lighting scenarios. The study found that changes in the reference chromaticity have a stronger effect on the elongation of the chromatic discrimination ellipses, and the reliability of the ellipse test results depends on the relation between the measurement directions and the confusion directions.
PERIODICA POLYTECHNICA-MECHANICAL ENGINEERING
(2022)
Review
Medicine, General & Internal
Adel Molnar, Peter Studinger, Nora Ledo
Summary: The heterogeneity of ANCA-associated vasculitis poses challenges for diagnosis and management, despite the increasing incidence of the disease. Prompt diagnosis and early treatment initiation are crucial for favorable patient and renal outcomes. A better understanding of the pathogenesis leads to more targeted and less toxic treatments.
FRONTIERS IN MEDICINE
(2022)
Article
Robotics
Bertalan Pizag, Daniel Kacz, Balazs Vince Nagy
Summary: This study investigates the possibility of automated lighting measurement using drones and presents simple models to evaluate the effect of positioning errors on the measurements' performance. It outlines the limitations of similar systems and highlights the ideal measurement range. Experimental results from a proof-of-concept prototype device confirm the findings and provide guidelines for the development of an in-situ photometric measurement device.
JOURNAL OF FIELD ROBOTICS
(2022)
Article
Optics
Min Gao, Balazs Vince Nagy
Summary: Improving Ganzfeld design for human and animal research, this study investigates the impact of geometric parameters on luminance uniformity. Using the 2FI method for experimental design and optimization, the study finds that the angle and length of the light source tube significantly affect uniformity.
Article
Ophthalmology
Regina Lukacs, Miklos Schneider, Zoltan Zsolt Nagy, Gabor Laszlo Sandor, Kinga Kaan, Antonia Asztalos, Lajos Enyedi, Gyorgy Pek, Gyorgy Barcsay, Antal Szabo, Agnes Borbandy, Illes Kovacs, Miklos Denes Resch, Andras Papp
Summary: This study assessed the long-term benefits of intensive aflibercept and ranibizumab anti-VEGF therapy in patients with exudative AMD. The results showed that both treatments can maintain or improve visual acuity in the long term, but prolonged intensive therapy and regular follow-up are necessary.
Review
Ophthalmology
Jakob Bjerager, Miklos Schneider, Ivan Potapenko, Elon H. C. van Dijk, Carsten Faber, Jakob Grauslund, Kristina Pfau, Josef Huemer, Danson V. Muttuvelu, Marie L. R. Rasmussen, M. Cem Sabaner, Yousif Subhi
Summary: Patients with nonneovascular AMD are encouraged to use the Amsler grid test for self-assessment, but its sensitivity is not recommended for monitoring. Ophthalmic examination should be regularly conducted regardless of the results of Amsler grid self-assessment.
JAMA OPHTHALMOLOGY
(2023)
Review
Ophthalmology
Janni M. E. Larsson, Lars C. Boberg-Ans, Andreas Vangsted, Elon H. C. van Dijk, Jakob Grauslund, Javad N. Hajari, Oliver N. Klefter, Miklos Schneider, Yousif Subhi
Summary: This systematic review and meta-analysis examined the efficacy of topical NSAIDs for the treatment of CSC. Thirteen eligible studies involving 1001 eyes of 994 patients were included. The findings showed a slight improvement in visual acuity at 1-month follow-up, but no statistically significant difference at 3-month follow-up. In addition, there was no clear benefit in complete subretinal fluid resolution. Therefore, the current evidence does not support the use of topical NSAIDs for CSC treatment.
ACTA OPHTHALMOLOGICA
(2023)
Article
Ophthalmology
Eva Volek, Gabor Laszlo Sandor, Zoltan Zsolt Nagy, Miklos Schneider
Summary: In this case report, an organic intralamellar foreign body was successfully diagnosed, planned for surgery, and monitored using noninvasive anterior segment optical coherence tomography (AS-OCT).
SPEKTRUM DER AUGENHEILKUNDE
(2023)
Article
Multidisciplinary Sciences
Orsolya Angeli, Dorottya Hajdu, Aniko Jeney, Balint Czifra, Balazs Vince Nagy, Tamas Balazs, Dora Jakaboczkine Nemoda, Gabor Mark Somfai, Zoltan Z. Nagy, Tunde Peto, Miklos Schneider
Summary: The aim of this study was to compare the qualitative and quantitative differences in vascular density analysis between an established method and a novel alternative for post-processing on optical coherence tomography angiography (OCTA) images. The results showed that there were significant differences in vessel density and skeleton density between the two methods, while the vessel diameter index was higher with the novel method. The noise level reduction was similar for both methods. Although both methods allowed for vascular network segmentation and examination, they produced largely inconsistent results, highlighting the importance of understanding the image analysis method for reliable decision making in retinal pathology patients. The use of the same image processing method is recommended for longitudinal monitoring.
SCIENTIFIC REPORTS
(2023)
Meeting Abstract
Ophthalmology
Mirella Telles Salgueiro Barboni, Agnes Urbin, Marton Edelmeyer, Otto Alexander Maneschg, Petra Killik, Janos Nemeth, Zoltan Nagy, Eva Maria Banko, Balazs Vince Nagy
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)