Dipeptide repeat protein and TDP-43 pathology along the hypothalamic–pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases

An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology

(2019) Lieselot Dedeene et al.   ACTA NEUROPATHOLOGICA

C9orf72-specific phenomena associated with frontotemporal dementia and gastrointestinal symptoms in the absence of TDP-43 aggregation

(2019) Paul J. Sampognaro et al.   ACTA NEUROPATHOLOGICA

Neuroendocrine Disturbances in Neurodegenerative Disorders: A Scoping Review

(2019) Amy Newhouse et al.   PSYCHOSOMATICS

Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases

(2019) Lieselot Dedeene et al.   Acta Neuropathologica Communications

Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease

(2018) Nobutaka Sakae et al.   Acta Neuropathologica Communications

C9orf72-mediated ALS and FTD: multiple pathways to disease

(2018) Rubika Balendra et al.   Nature Reviews Neurology

Plurihormonal cells of normal anterior pituitary: Facts and conclusions

(2017) Lubov B. Mitrofanova et al.   Oncotarget

Timing and significance of pathological features inC9orf72expansion-associated frontotemporal dementia

(2016) Sarat C. Vatsavayai et al.   BRAIN

Hypothalamic α-synuclein and its relation to weight loss and autonomic symptoms in Parkinson's disease

(2016) Eduardo De Pablo-Fernandez et al.   MOVEMENT DISORDERS

Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing

(2015) Martin H. Schludi et al.   ACTA NEUROPATHOLOGICA

Metabolic and Non-Cognitive Manifestations of Alzheimer’s Disease: The Hypothalamus as Both Culprit and Target of Pathology

(2015) Makoto Ishii et al.   Cell Metabolism

TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis

(2014) Matthew D Cykowski et al.   Acta Neuropathologica Communications

Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations

(2013) Ian R. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

(2013) Peter E.A. Ash et al.   NEURON

Evaluation of Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone

(2013) David J. Irwin et al.   JAMA Neurology

A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results

(2011) Francesco Saccà et al.   JOURNAL OF NEUROLOGY

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

Phosphorylated α-synuclein immunoreactivity in the posterior pituitary lobe

(2011) Taku Homma et al.   NEUROPATHOLOGY

The GH-IGF system in amyotrophic lateral sclerosis: correlations between pituitary GH secretion capacity, insulin-like growth factors and clinical features

(2009) M. T. Pellecchia et al.   EUROPEAN JOURNAL OF NEUROLOGY