Review
Microbiology
Tharuka Wijesekara, Baojun Xu
Summary: The study examines the intricate relationship between plants and the endophytic fungi inhabiting their tissues. These fungi coexist with plants, forming a symbiotic connection that has potential implications for plant health and growth. The bioactive compounds produced by these fungi hold promise for human health.
Article
Infectious Diseases
Sundaram Muthukrishnan, Paranivasakam Prakathi, Thangavel Sivakumar, Muthu Thiruvengadam, Bindhu Jayaprakash, Venkidasamy Baskar, Maksim Rebezov, Marina Derkho, Gokhan Zengin, Mohammad Ali Shariati
Summary: Endophytic fungi residing in medicinal plants have the potential to produce various bioactive compounds. In this study, three endophytic fungi were isolated from different medicinal plants and their intra- and extracellular products were analyzed. The analysis revealed the presence of bioactive metabolites and phytochemicals, and the extracts exhibited strong antibacterial and antioxidant activity. Molecular docking analysis also suggested the potential anticancer activity of certain compounds. These findings highlight the importance of endophytic fungi in natural drug development and reducing the environmental burden of synthetic drugs.
Article
Chemistry, Physical
Marcin Rosowski, Dorota Puchowicz, Monika Jaskulska, Jan Kozlowski, Malgorzata Cieslak
Summary: Invasive slugs pose significant challenges in horticultural and agricultural production. Despite various methods to control the pest population, an effective plant protection strategy has yet to be developed. This paper proposes a solution utilizing modified non-woven fabric with bioactive molluscicidal properties to mitigate slug infestations and protect plants from harm.
Article
Microbiology
Akram H. Mohamed, Fayrouz H. Abd El-Megeed, Naziha M. Hassanein, Sameh H. Youseif, Peter F. Farag, Saleh A. Saleh, Basel A. Abdel-Wahab, Amnah Mohammed Alsuhaibani, Yosra A. Helmy, Ahmed M. Abdel-Azeem
Summary: This study aims to explore the potential of native fungi associated with wild plants to enhance wheat yields and investigate their plant growth-promoting traits. The results demonstrate that some fungi exhibit high plant growth-promoting activity and significantly improve wheat yields and nutrient content under reduced chemical nitrogen fertilization.
Article
Entomology
Jonathan Cisneros, Justin Wendel, Stefan Jaronski, Christopher Vitek, Matthew Ciomperlik, Daniel Flores
Summary: This study collected samples of the Asian citrus psyllid from the Lower Rio Grande Valley in Texas and identified two new strains of entomopathogenic fungi that may be beneficial for managing psyllid populations.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Environmental Sciences
Arjun Kumar Kalimuthu, Pavadai Parasuraman, Pandian Sivakumar, Sankaranarayanan Murugesan, Sankarganesh Arunachalam, Sureshbabu Ram Kumar Pandian, Vigneshwaran Ravishankar, Damodar Nayak Ammunje, Muthukumar Sampath, Theivendran Panneerselvam, Selvaraj Kunjiappan
Summary: This study aims to discover novel phytochemical substances from endophytic fungus in medicinal plants, with Curvularia geniculata L. showing potential antioxidant and anticancer properties. The identified compound 2-methyl-7-phenylindole exhibited high binding affinity for EGFR. The fungal extract demonstrated strong antioxidant activity and concentration-dependent cytotoxicity against HepG2 cells, inducing apoptosis and targeting mitochondrial integrity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Agricultural Engineering
Luana A. Lima, Paula S. Ferreira-Sa, Manoel D. N. Garcia Jr, Vera Lucia P. Pereira, Jose Carlos T. Carvalho, Leandro Rocha, Caio P. Fernandes, Raimundo Nonato P. Souto, Raquel S. Araujo, Gisele Botas, Rodrigo A. S. Cruz
Summary: Nano-emulsions containing essential oil from B. reticularia and some of its monoterpene constituents showed significant repellent activity against Tribolium castaneum, indicating potential for their use as ecofriendly nanopesticides.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Review
Biochemistry & Molecular Biology
Bahman Zamani Amirzakariya, Abolfazl Shakeri
Summary: Plant endophytes are important sources of bioactive compounds, particularly terpenoids. This review summarizes the newly isolated terpenoids from plant endophytic fungi and their biological activities from 2011 to 2020.
Article
Entomology
Mitchell L. Helton, Nicholas A. Tinsley, Anthony J. McMechan, Erin W. Hodgson
Summary: Soybean gall midge is a newly identified pest that has caused severe economic loss to soybean fields in several states in the US. In order to assess the severity of plant injury, researchers developed an injury rating system and found that it correlates well with yield loss caused by the larvae. This system may be an important tool for understanding the economic impact of this emergent pest.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Microbiology
Rosario Nicoletti, Andrea Becchimanzi
Summary: Insects and fungi are widespread groups of organisms that have significant impacts on agriculture and human activities. They can interact with each other and establish various symbiotic relationships, influencing the harmful effects of both organisms and the management practices adopted to counteract them.
Article
Multidisciplinary Sciences
Sebastian A. Pelizza, Natalia A. Ferreri, Lorena A. Eliades, Betina Galarza, Marta N. Cabello, Maria L. Russo, Florencia Vianna, Ana C. Scorsetti, Carlos E. Lange
Summary: The first barrier for microorganisms like fungi when penetrating an insect host is the insects cuticle; fungi produce a wide variety of extracellular enzymes involved in the degradation of protein, chitin, and lipids; C. locustiphila shows potential as a biological control agent for the South American locust.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Juntai Zhu, Lixia Song, Shengnan Shen, Wanxin Fu, Yaying Zhu, Li Liu
Summary: This review focuses on Aspergillus-derived alkaloids, compounds with diverse biological activities and structural diversity.
Article
Biochemical Research Methods
Shubha Jagannath, Narasimhamurthy Konappa, Arpitha Lokesh, Bhuvaneshwari, Tejaswini Dasegowda, Arakere C. Udayashankar, Srinivas Chowdappa, Maya Cheluviah, Praveen Satapute, Sudisha Jogaiah
Summary: In this study, 203 endophytic fungi were isolated from Baliospermum montanum, showing potential medicinal value with 70% containing alkaloids and flavonoids. Gas chromatography-mass spectrometry analysis detected multiple bioactive compounds produced by these endophytic fungi.
ANALYTICAL BIOCHEMISTRY
(2021)
Article
Agronomy
Ada Frattini, Maria Martinez-Solis, Angel Llopis-Gimenez, Maria J. Pozo, Javier Rivero, Cristina M. Crava, Salvador Herrero
Summary: This study provides the first evidence of compatibility between tomato plants and AMF symbiosis with bacterial and viral entomopathogens, contributing to the development of novel approaches for biological pest control.
PEST MANAGEMENT SCIENCE
(2022)
Article
Microbiology
Gaoran Liu, Ruiyun Huo, Yanan Zhai, Ling Liu
Summary: Three new secondary metabolites were isolated from the endophytic fungus of tea tree, with compound 6 showing moderate cytotoxicity against T24 and MCF7 cell lines. The compounds were also evaluated for antibacterial activity.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Applied
Maria Michela Salvatore, Marina DellaGreca, Rosario Nicoletti, Francesco Salvatore, Angela Tuzi, Gaetano De Tommaso, Artur Alves, Alla Eddine Mahamedi, Akila Berraf-Tebbal, Anna Andolfi
Summary: Mitidjospirone, a new spiridioxynaphthalene, was isolated from the mycelial extract of Lasiodiplodia mitidjana, and its structure and absolute configuration were determined through spectroscopic analysis and electronic circular dichroism. Additionally, several known compounds were identified during the screening of secondary metabolites produced by L. mitidjana.
NATURAL PRODUCT RESEARCH
(2023)
Article
Microbiology
Rosario Nicoletti, Andrea Becchimanzi
Summary: This paper discusses the mutualistic and antagonistic relationships between species of the genus Talaromyces and insects, as well as their ability to synthesize bioactive compounds possibly involved in the latter kind of interactions, with reference to the ecological impact and applicative perspectives in crop protection.
Article
Microbiology
Rosario Nicoletti, Andrea Becchimanzi
Summary: Insects and fungi are widespread groups of organisms that have significant impacts on agriculture and human activities. They can interact with each other and establish various symbiotic relationships, influencing the harmful effects of both organisms and the management practices adopted to counteract them.
Article
Biology
Donata Molisso, Mariangela Coppola, Martina Buonanno, Ilaria Di Lelio, Simona Maria Monti, Chiara Melchiorre, Angela Amoresano, Giandomenico Corrado, John Paul Delano-Frier, Andrea Becchimanzi, Francesco Pennacchio, Rosa Rao
Summary: Prosystemin is not only a precursor of Systemin peptide, but also contains other biologically active regions. Experimental results show that truncated Prosystemin can promote defense barriers in tomato plants through a hormone-independent defense pathway, and provide protection against pests and pathogens.
Review
Food Science & Technology
Maria Michela Salvatore, Anna Andolfi, Rosario Nicoletti
Summary: Hazelnuts are increasingly consumed worldwide, but they pose a potential public health risk as a source of mycotoxins. This review examines the available data on mycotoxins in hazelnuts, the fungal species infecting hazelnut fruit, and the analytical methods used for mycotoxin investigation. A broad range of fungal species and mycotoxins have been detected in hazelnuts, emphasizing the need for methods that can detect multiple mycotoxins simultaneously. Control strategies for fungal contamination and mycotoxin reduction in hazelnuts are also discussed.
Review
Agronomy
Rosario Nicoletti, Beata Zimowska
Summary: The results of extensive research conducted worldwide in recent decades have shown that endophytic fungi play a crucial role in enhancing plant fitness by promoting growth and acting as defensive mutualists. These properties have potential applications in crop production, especially for tree species like hazelnuts grown extensively in semi-natural environments throughout temperate zones. This paper reviews the available data on the occurrence, ecological roles, and biotechnological applications of endophytic fungi associated with hazelnuts, aiming to provide a reference for future investigations and projects aimed at harnessing the potential of this component of the plant microbiome.
PLANT PROTECTION SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Rosario Nicoletti, Rosa Bellavita, Annarita Falanga
Summary: Fungi in the genus Talaromyces are found in various environments and are often associated with plants and animals. This review focuses on marine-derived Talaromyces strains and their potential for biosynthesis. More than 500 secondary metabolites were extracted from axenic cultures of these isolates, with about 45% identified as new products. These compounds belong to different chemical classes and show a wide range of biological properties, making these fungi a valuable resource for biotechnological applications.
Review
Microbiology
Rosario Nicoletti, Anna Andolfi, Andrea Becchimanzi, Maria Michela Salvatore
Summary: Due to their widespread occurrence, fungi in the genus Penicillium are commonly found in association with insects. This symbiotic interaction has been investigated to explore their potential for ecofriendly pest control strategies. The assumption is that Penicillium species, known for producing bioactive secondary metabolites, may have entomopathogenic properties. This review paper examines the properties and potential applications of compounds from Penicillium fungi in insect pest management.
Article
Chemistry, Applied
Maria Michela Salvatore, Rosario Nicoletti, Maria Teresa Russo, Alla Eddine Mahamedi, Akila Berraf-Tebbal, Marina DellaGreca, Andolfi Anna
Summary: In this study, 6-methylpyridione analogues were isolated and identified for the first time in liquid cultures of Dothiorella sarmentorum isolated from symptomatic grapevine in Algeria.
NATURAL PRODUCT RESEARCH
(2023)
Article
Infectious Diseases
Claudia Cerracchio, Maria Michela Salvatore, Luca Del Sorbo, Francesco Serra, Maria Grazia Amoroso, Marina Dellagreca, Rosario Nicoletti, Anna Andolfi, Filomena Fiorito
Summary: Recent studies have found that 3-O-methylfunicone (OMF), a fungal secondary metabolite, has antiviral activity against canine coronaviruses (CCoV). In this study, we also investigated the inhibitory activity of two similar compounds, vermistatin (VER) and penisimplicissin (PS), against CCoV infection. The results showed that these compounds can inhibit CCoV infection without cytotoxicity within certain concentrations.
Review
Agronomy
Rosario Nicoletti, Beata Zimowska
Summary: Results of extensive research conducted worldwide have shown that endophytic fungi play a crucial role in enhancing plant fitness by promoting growth and acting as defensive mutualists. These properties have potential applications in crop production, particularly for tree species like hazelnut that are extensively cultivated in highland regions. This paper provides a review of the available data on the occurrence, ecological roles, and biotechnological applications of endophytic fungi associated with hazelnuts, aiming to support future investigations and projects focused on harnessing the potential of this component of the plant microbiome.
PLANT PROTECTION SCIENCE
(2023)
Review
Horticulture
Rosario Nicoletti, Milena Petriccione, Martina Curci, Marco Scortichini
Summary: The cultivation of hazelnut has expanded globally due to the increased demand for raw materials by the food industry. Bacterial diseases pose a major threat to hazelnut farmers, but progress has been made in controlling these diseases through various methods. In addition, plant growth-promoting rhizobacteria and other microorganisms play a significant role in hazelnut nutrition and protection.
Review
Horticulture
Maria Michela Salvatore, Rosario Nicoletti, Anna Andolfi
Summary: Citrus essential oils are widely used in the food, pharmaceutical, cosmetical, and chemical industries. They play a crucial role in the quality of citrus fruits by providing natural protection against postharvest deteriorations. Various factors influence the assortment and accumulation of essential oils in citrus peels, which have implications for the postharvest quality of the fruit.
