Review
Pharmacology & Pharmacy
Heping Wang, Bowen Xu, Ying Zhang, Yuanyuan Duan, Ruike Gao, Haoqiang He, Xiuyang Li, Jie Li
Summary: This study summarizes the latest evidence of TCM in COVID-19, showing that TCM plus routine treatment is significantly better than routine treatment alone in clinical cure and chest image improvement, while reducing the occurrence of some severe conditions. There was no overall significant difference in safety outcomes between the two groups.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Ming Lyu, Guanwei Fan, Guangxu Xiao, Taiyi Wang, Dong Xu, Jie Gao, Shaoqin Ge, Qingling Li, Yuling Ma, Han Zhang, Jigang Wang, Yuanlu Cui, Junhua Zhang, Yan Zhu, Boli Zhang
Summary: The COVID-19 pandemic poses a significant threat to global public health and safety, with the crucial role and potential mechanisms of Traditional Chinese Medicine (TCM) in combination with Western medicine highlighted and discussed. A comprehensive review of the clinical effects and potential mechanisms of TCM on COVID-19 is presented, aiming to provide reference for healthcare professionals and the public, and facilitate understanding of the true scientific value of TCM.
ACTA PHARMACEUTICA SINICA B
(2021)
Article
Plant Sciences
David Y. W. Lee, Qing Y. Li, Jing Liu, Thomas Efferth
Summary: Traditional Chinese herbal medicine has a long history of combatting epidemics, with hundreds of herbal formulas developed for prevention and treatment. During the COVID-19 outbreak in Wuhan, TCM showed over 90% efficacy, attributed to restoring the balance of the immune system. Certain herbal preparations targeting the lung meridian provided relief for lung congestion and diarrhea, characteristic symptoms of COVID-19.
Article
Pharmacology & Pharmacy
Wei Huang, Bo Jiang, Jinli Luo, Meng Luo, Xiaoming Ding, Qian Yang, Lin-Hua Zhao, Qin-Guo Sun, Xiao-Lin Tong
Summary: The study investigated the effectiveness of combining traditional Chinese medicine (TCM) and Western medicine for COVID-19 patients undergoing hemodialysis. The results showed that the combination treatment group had better symptom relief, improved laboratory indicators, and higher treatment success rate compared to the control group.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Yi-Chang Su, Guan-Jhong Huang, Jaung-Geng Lin
Summary: This article reviews the use of traditional Chinese medicine (TCM) in the treatment of COVID-19 and analyzes its potential antiviral, anti-inflammatory, and immunomodulatory activities. The study finds that many TCM components can target multiple pathways and have the potential to prevent and treat COVID-19. Therefore, TCM may be an effective treatment option.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Medicine, Research & Experimental
Zhihua Yang, Yangxi Liu, Lin Wang, Shanshan Lin, Xiangdong Dai, Haifeng Yan, Zhao Ge, Qiuan Ren, Hui Wang, Feng Zhu, Shuping Wang
Summary: COVID-19 can cause gastrointestinal symptoms due to disruption of the gut microbiota. Traditional Chinese medicine has advantages in regulating the gut microbiota and has shown significant efficacy in the prevention and treatment of COVID-19.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Review
Integrative & Complementary Medicine
Liang Chu, Fang Huang, Mengdan Zhang, Biao Huang, Yigang Wang
Summary: The ongoing outbreak of COVID-19 caused by SARS-CoV-2 began in December 2019, with clinical characteristics and treatment progress summarized. Despite the established clinical manifestations, there are still no specific drugs to treat COVID-19; however, traditional Chinese medicine has been utilized in China with some success, including improved ancient TCM prescriptions.
Review
Pharmacology & Pharmacy
Ziqi Chen, Yiwen Lv, Huachong Xu, Li Deng
Summary: COVID-19 is a respiratory disease caused by a virus, with symptoms ranging from mild to life-threatening. Some patients also experience gastrointestinal symptoms. Herbal medicine may play a role in recovering intestinal flora structure and modulating immune function for the treatment and recovery of COVID-19.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Integrative & Complementary Medicine
Qiao Zhang, Shijun Yue, Wenxiao Wang, Yanyan Chen, Chongbo Zhao, Yijun Song, Dan Yan, Li Zhang, Yuping Tang
Summary: The review discusses the relationship between COVID-19 and gut microbiota, suggesting that a combination of traditional Chinese medicine and western medication may be an effective treatment strategy. Data indicates that gut microbiota dysbiosis occurs in COVID-19 patients and that intervention in gut microbiota can improve the clinical condition of patients. Certain Chinese herbs have shown to have a regulatory effect on gut microbiota, immunity, and ACE2, with the possibility of gut microbiota mediating the efficacy of TCM treatment for COVID-19.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2021)
Review
Medicine, Research & Experimental
Xuedong An, YueHong Zhang, Liyun Duan, De Jin, Shenghui Zhao, RongRong Zhou, Yingying Duan, Fengmei Lian, Xiaolin Tong
Summary: SARS-CoV-2 has caused a global pandemic with millions of cases and deaths, and while traditional Chinese medicine (TCM) has shown effectiveness in treating COVID-19, the need for international cooperation in establishing guidelines for its use in diverse populations remains. Further research on TCM's efficacy in psychological abnormalities related to COVID-19 is also necessary to provide a comprehensive understanding of its role in prevention, treatment, and recovery efforts.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Integrative & Complementary Medicine
Jillian L. Capodice, Barbara M. Chubak
Summary: Traditional Chinese Medicine (TCM) is a comprehensive medical system that has been developed over thousands of years and is utilized in the treatment of COVID-19. This paper highlights the use of TCM in treating COVID-19, discussing concepts and challenges of integrating TCM into medical settings.
Review
Immunology
David Setyo Budi, Ihsan Fahmi Rofananda, Nando Reza Pratama, Henry Sutanto, Arisvia Sukma Hariftyani, Saskia Ratna Desita, Aulia Zinedinita Rahmasari, Tri Pudy Asmarawati, Langgeng Agung Waskito, Citrawati Dyah Kencono Wungu
Summary: The study evaluated the benefits and side effects of ozone as an adjuvant therapy in COVID-19 patients. The results showed that ozone therapy reduced mortality and improved certain clinical and laboratory outcomes. However, it did not improve other endpoints such as length of hospital stay and ICU admission. Ozone therapy seems to be beneficial in improving laboratory parameters among severe COVID-19 patients and has a high safety profile.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Fui Fui Lem, Fernandes Opook, Dexter Jiunn Herng Lee, Fong Tyng Chee, Fahcina P. Lawson, Su Na Chin
Summary: This systematic scoping review aims to provide an overview of the molecular mechanism of action of repurposed drugs or alternative treatment medicines used to attenuate COVID-19 disease. The results show that both repurposed drugs and Traditional Chinese Medicine play a role in inhibiting the proliferation of the SARS-CoV-2 virus through different mechanisms.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Integrative & Complementary Medicine
Le-peng Zhou, Jie Wang, Ri-hua Xie, Smita Pakhale, Daniel Krewski, D. William Cameron, Shi Wu Wen
Summary: This study suggests that Traditional Chinese Medicine (TCM) as an auxiliary treatment for COVID-19 may increase the cure rate, relieve cough, improve chest CT images, and reduce disease progression. However, the certainty of evidence for some outcomes is limited, and further research is needed to draw more definitive conclusions.
JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
(2021)
Article
Integrative & Complementary Medicine
Ting Hu, Li Li, Qin Ma
Summary: SARS-CoV-2 poses a global health threat due to its high transmission and virulence. Traditional Chinese medicine (TCM) plays a significant role in treating COVID-19, with many frequently used Chinese medicines found to contain flavonoids. This study discusses the structure and function of flavonoids, which can bind to key proteins of the virus or block the virus from entering human cells. It also explores the effects of flavonoids on the respiratory, digestive, and immune systems. The findings aim to provide guidance for clinical drug treatment and promote the international development of TCM.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2023)
Review
Neurosciences
Wei-Xing Pan, Arthur Yin Fan, Shaozong Chen, Sarah Faggert Alemi
Summary: Acupuncture, as a quick and noninvasive technique of peripheral nerve stimulation, has emerged as a promising therapy for immunomodulation in acute inflammation. It activates somatic-autonomic-immune reflexes to provide systemic effects, as well as local reflexes to generate local effects. These mechanisms offer scientific guidance for designing acupuncture protocols for immunomodulation and inflammation control.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
(2021)
Article
Integrative & Complementary Medicine
Xin Yin, Shu-bin Cai, Lan-ting Tao, Lu-ming Chen, Zhong-de Zhang, Su-hong Xiao, Arthur Yin Fan, Xu Zou
Summary: In a study conducted on a severe COVID-19 patient in Wuhan, China, the combination of manual acupuncture and Chinese herbal medicine showed promising results, improving the patient's respiratory function, increasing oxygen saturation, and reducing heart rate. The use of acupuncture and herbs together as adjuvants to standard care may achieve better outcomes in treating severe cases of COVID-19.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2021)
Editorial Material
Integrative & Complementary Medicine
Arthur Yin Fan
Summary: An international study published in the journal Nature in October 2021 investigated the use of electroacupuncture (EA) for treating inflammation. The study found that acupuncture can achieve a distal effect by stimulating the vagus-adrenal axis, and that different acupuncture stimulation intensities or depths can have different therapeutic effects.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2023)
Article
Integrative & Complementary Medicine
Arthur Yin Fan, Sarah Faggert Alemi
Summary: This article introduces Dr. Lian Zhu, MD, who made significant contributions to the development and promotion of acupuncture in China. Dr. Zhu was one of the earliest acupuncture trainers in the Chinese military health system and played a crucial role in overcoming resource shortages during the Chinese Civil War. She also established the first public acupuncture university and two key acupuncture institutes in China, promoting acceptance of medical acupuncture through research and education.
MEDICAL ACUPUNCTURE
(2023)
Review
Integrative & Complementary Medicine
Mingzhu Ye, Arthur Yin Fan, Sarah Faggert Alemi
Summary: The study analyzed and discussed the historical development of Jiao's scalp acupuncture (SA) system, the composition of the stimulation zones, and the projection of the cerebral cortex's function zones on the scalp. The findings revealed that the stimulation zones in Jiao's SA system were a mix of Jiao's speculation and other authors' clinical experiences, causing confusion. Furthermore, Jiao's projection of the cerebral cortex's function zones on the scalp was based on brain surgery marks and his belief that needling those lines could treat cerebrovascular diseases, which lacked evidence.
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
(2023)
Article
Medical Informatics
Bill Reddy, Arthur Yin Fan
Summary: Traditional medicine is widely practiced globally, but there is limited information systems and standardization. The inclusion of traditional medicine in the new ICD-11 allows for international standardization and sharing.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Review
Integrative & Complementary Medicine
Arthur Yin Fan, Sarah Faggert Alemi, Yong-Ming Li
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
(2020)
Article
Integrative & Complementary Medicine
Arthur Yin Fan, Deguang He, Sherman Gu, Haihe Tian, Hui Ouyang, Hui Wei, Changzhen Gong, Sarah Faggert Alemi, Xiaoyin Zhao
MEDICAL ACUPUNCTURE
(2020)
Review
Integrative & Complementary Medicine
Arthur Yin Fan, Hui Wei, Haihe Tian, Jane Huang, Sarah Faggert Alemi
MEDICAL ACUPUNCTURE
(2020)
Article
Integrative & Complementary Medicine
Sherman Gu, Arthur Yin Fan
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2020)
Article
Integrative & Complementary Medicine
Arthur Yin Fan, David Dehui Wang, Hui Ouyang, Haihe Tian, Hui Wei, Deguang He, Changzhen Gong, Jipu Wen, Ming Jin, Chong He, Sarah Faggert Alemi, Sudaba Rahimi
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2019)
Article
Integrative & Complementary Medicine
Stephanie Pina, Ming Jin, Arthur Yin Fan
MEDICAL ACUPUNCTURE
(2019)
Article
Integrative & Complementary Medicine
Arthur Yin Fan, Hui Ouyanga, Xinru Qian, Hui Wei, David Dehui Wang, Deguang He, Haihe Tian, Changzhen Gone, Amy Matecki, Sarah Faggert Alemi
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2019)
Article
Integrative & Complementary Medicine
Arthur Yin Fan, Sarah F. Alemi, Yingping H. Zhu, Sudaba Rahimi, Hui Wei, Haihe Tian, Deguang He, Changzhen Gong, Guanhu Yang, Chong He, Hui Ouyang
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2018)