Article
Environmental Sciences
Nazish Iftikhar, Rabeea Zafar, Imran Hashmi
Summary: This study investigated the bioaccumulation and sub-lethal toxicity of sulfamethoxazole in Cyprinus carpio. It was found that sulfamethoxazole accumulated in the fish muscle tissues and induced oxidative stress and histopathology. The production of reactive oxygen species (ROS) and the severity of tissue damage were dose and time dependent.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Nilce Mary Turcatti Folle, Maristela Azevedo-Linhares, Juan Ramon Esquivel Garcia, Luise Esquivel, Sonia Regina Grotzner, Elton Celton de Oliveira, Francisco Filipak Neto, Ciro Alberto de Oliveira Ribeiro
Summary: The study investigated the effects of TBP on Oreochromis niloticus, finding that exposure to TBP could affect the hepatosomatic index, erythrocyte parameters, biochemical endpoints, and histopathological analysis. Male fish were more sensitive to TBP exposure, showing increased vitellogenin expression, CAT activity, and liver lesions. Antioxidant mechanisms and cholinesterase activity effects were more pronounced in males than females.
Review
Plant Sciences
Lilianna Sharma, Grzegorz Siedlewicz, Ksenia Pazdro
Summary: Antibiotic residues are commonly detected worldwide in various aquatic ecosystems, with a focus on marine microalgae. A review highlighted significant knowledge gaps in the toxic effects of antibiotics, emphasizing the need for future research to include chronic effects studies and consider mixture effects and combined environmental factors.
Article
Environmental Sciences
Kaouthar Kessabi, Amira Abbassi, Samar Lahmar, Marta Casado, Mohamed Banni, Benjamin Pina, Imed Messaoudi
Summary: The study investigated the potential ecological risks of microplastics (MPs) and cadmium (Cd) exposure in Aphanius fasciatus. While Cd exposure led to increased metallothioneins levels and oxidative stress response in liver and gills, MPs had a major impact on gills and induced spinal deformities. However, the simultaneous exposure to both pollutants showed similar effects as individual exposure, possibly due to reduced bioavailability of Cd.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Environmental
Jing Ji, Liang Peng, Tianpeng Gao, El-Sayed Salama, Aman Khan, Pu Liu, Hui Yun, Xiangkai Li
Summary: This study investigated the combined effects of polystyrene (PS) and sulfamethoxazole (SMX) on the granulation, performance, and antibiotic resistance genes (ARGs) of aerobic granular sludge. The results showed that PS enhanced the toxic effects of SMX on microorganisms, delaying the granulation process and increasing the abundance of ARGs. Microbes responded to this combined toxicity by increasing the synthesis of cheap amino acids and polysaccharides to secrete a greater amount of extracellular polymeric substances.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Young-Bin Yu, Jae-Ho Choi, Cheol Young Choi, Ju-Chan Kang, Jun-Hwan Kim
Summary: The aim of this study is to assess the toxic effects of polyethylene microplastics (PE-MPs) on crucian carp by examining bioaccumulation, hematological parameters, and antioxidant responses. Results showed that the accumulation of PE-MPs in different tissues of crucian carp increased with the concentration, with the highest accumulation in the intestine, followed by the gills and liver. Hematological parameters, plasma components, and antioxidant responses were significantly affected by PE-MPs in a concentration-dependent manner. Exposure to >= 32 mg/L of PE-MPs resulted in a significant decrease in red blood cells, hemoglobin content, and hematocrit values. Additionally, exposure to >= 32 mg/L of PE-MPs induced oxidative stress in the liver, gills, and intestine, leading to elevated levels of superoxide dismutase, catalase, and glutathione S-transferase, and decreased glutathione levels. The interaction between PE-MPs and exposure periods did not produce significant changes.
Article
Biochemistry & Molecular Biology
Rehab A. Azouz, Reda M. S. Korany
Summary: The study demonstrated that exposure to 1000 ppm silica nanoparticles resulted in severe hepatorenal toxicity in rats, characterized by oxidative stress, liver and kidney dysfunction, and histopathological and immunohistochemical alterations.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Rayees Ahmad Bhat, Shima Bakhshalizadeh, Maria Cristina Guerrera, Osman Sabri Kesbic, Francesco Fazio
Summary: This study aimed to assess the severity of pollution impact on rainbow trout ovaries in two different hatcheries. The results revealed that fish from Panzath hatchery exhibited various deformities and irregularly shaped oocytes, while fish from Verinag hatchery showed normal ovarian structure. Fish from Panzath hatchery also exhibited DNA damage, cellular apoptosis, and oxidative damage, while fish from Verinag hatchery did not. In conclusion, pollution has a direct impact on fish growth and reproduction in aquaculture practices.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2023)
Article
Engineering, Environmental
A. P. Habeeb Rahman, Pranjal, Susanta Kumar Beher, Amrita Mishra, Cecilia Stalsby Lundborg, Suraj K. Tripathy
Summary: Bacterial adaptation to external stress and its evolution to antibiotic resistance poses a risk to the health sector. Conventional wastewater treatment may disseminate antibiotic resistance, but new technologies are emerging. This study found that stress-adapted bacteria survived SPC treatment for a longer time compared to unadapted bacteria.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Infectious Diseases
Jia Du, Qinghua Liu, Ying Pan, Shaodan Xu, Huanxuan Li, Junhong Tang
Summary: This paper summarizes the occurrence, fate, and ecotoxicity of fluoroquinolone antibiotics in various environmental media. It reviews the toxicity effect on various organisms and compares the toxicology mechanisms. Gaps in toxicological investigations and the knowledge of natural transformation toward drug-resistant bacteria are identified.
Article
Environmental Sciences
Marium Fiaz, Iftikhar Ahmed, Sumara Masood Ul Hassan, Adnan Khan Niazi, Muhammad Fahim Khokhar, Muhammad Ansar Zeshan, Muhammad Ansar Farooq, Muhammad Arshad
Summary: Excessive use and release of antibiotics in the developing world have negatively impacted soil processes and crop growth. This study investigated the effects of oxytetracycline and levofloxacin on mung bean plants, showing decreased nitrate reductase activity and increased antioxidant enzyme activity. Lower concentrations of antibiotics increased nitrogen content and overall plant biomass, while higher concentrations decreased plant biomass and nitrogen content. Plants treated with levofloxacin and mixtures exhibited increased glutamine synthetase activity. Low doses of antibiotics had lower toxicity symptoms, but higher doses showed increased oxidative stress. The toxicity trend was levofloxacin > mixture > oxytetracycline.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Wei Liu, Yan Xu, Vera I. Slaveykova
Summary: Through studying the development mechanism of bacterial antibiotic resistance under sub-lethal copper ion exposure, it was found that oxidative stress can induce bacterial antibiotic resistance, and the increase in cell membrane permeability and the number of bacteria entering the viable but non culturable state are also contributing factors.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Xiuge Gao, Xiaoxiao Liu, Xinhao Song, Pei Teng, Hui Ji, Lin Peng, Yawei Qiu, Dawei Guo, Shanxiang Jiang
Summary: The study found that maduramicin has lethal toxicity to crayfish, affecting their biochemical parameters and tissue structure. After exposure, crayfish developed a certain degree of resistance to maduramicin.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Chemistry, Physical
Tanya Verma, Anchal Aggarwal, Shikha Singh, Sumit Sharma, Saurabh Jyoti Sarma
Summary: The discovery of antibiotics has significantly improved the treatment of infectious diseases and increased human life expectancy. However, the development of antibiotic resistance by microorganisms remains a major concern. The sensitivity and resistivity of bacteria play a crucial role in the effectiveness of antibiotics.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Environmental Sciences
Camila Guimaraes Torquetti, Thaynara Parente de Carvalho, Renata Maria Pereira de Freitas, Mariella Bontempo Freitas, Ana Tereza Bittencourt Guimaraes, Benito -Blanco
Summary: This study evaluated the health condition of bats from different food guilds captured in two areas with different land use profiles in Brazil and compared data on the oxidant-antioxidant balance and histopathological changes. Despite differences in land use and occupation, bats showed similar responses, but the trophic guilds were affected differently.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Microbiology
Roman Kotlowski, Katarzyna Grecka, Barbara Kot, Piotr Szweda
Review
Environmental Sciences
Bartosz Bojarski, Malgorzata Witeska
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2020)
Article
Multidisciplinary Sciences
Barbara Kot, Hubert Sytykiewicz, Iwona Sprawka, Malgorzata Witeska
SCIENTIFIC REPORTS
(2020)
Article
Agriculture, Dairy & Animal Science
Bartosz Bojarski, Oksana Buchko, Elzbieta Kondera, Katarzyna Lugowska, Artur Osikowski, Magdalena Trela, Malgorzata Witeska, Marcin W. Lis
Summary: Hexavalent chromium has various toxic effects and can affect the hatchability of chicken embryos in a dose-dependent manner. Lower doses of chromium may even increase hatchability, while LD50 levels do not cause significant changes in hematological parameters or liver histopathology in newly hatched chicks.
Article
Agriculture, Dairy & Animal Science
Elzbieta Kondera, Bartosz Bojarski, Katarzyna Lugowska, Barbara Kot, Malgorzata Witeska
Article
Infectious Diseases
Barbara Kot, Agata Gruzewska, Piotr Szweda, Jolanta Wicha, Urszula Parulska
Summary: This study in central Poland identified Escherichia coli and Klebsiella pneumoniae as the most common uropathogens causing urinary tract infections in hospitalized patients. Many strains showed resistance to common antibiotics, limiting treatment options.
Article
Biology
Bartosz Bojarski, Magdalena Socha, Ewa Drag-Kozak, Agnieszkaa Rombel-Bryzek, Sylwia Kapinos, Leszek Szala, Elzbieta Kondera, Katarzyna Lugowska, Malgorzata Witeska
Summary: The study compared the values of haematological and selected blood plasma biochemical parameters in juvenile common carp from blood samples taken from caudal vein and heart, revealing significant differences in red blood cell count and other parameters based on different blood sampling order.
FOLIA BIOLOGICA-KRAKOW
(2021)
Review
Fisheries
Malgorzata Witeska, Elzbieta Kondera, Katarzyna Lugowska, Bartosz Bojarski
Summary: Hematological analyses are commonly used in evaluating fish health and welfare, with results sensitive to various environmental factors. Both manual and automatic methods are utilized in fish hematology research.
Article
Environmental Sciences
Bartosz Bojarski, Mateusz Jakubiak, Pawel Szczerbik, Michal Bien, Artur Klaczak, Tomasz Stanski, Malgorzata Witeska
Summary: In this study, fish communities in inflow and outflow watercourses of two common carp fish farms were investigated. The results showed that escaped cultured fish and invasive alien species were found in the outflow canals, while the canals also harbored valuable endangered fish. It was demonstrated that fish ponds have an impact on neighboring watercourses and contribute to the species richness of ichthyofauna.
POLISH JOURNAL OF ENVIRONMENTAL STUDIES
(2022)
Article
Physiology
Elzbieta Kondera, Bartosz Bojarski, Katarzyna Lugowska, Barbara Kot, Malgorzata Witeska
Summary: The study showed that plant-origin antibacterial agents trans-cinnamaldehyde (TC) and thyme oil (TO) did not have significant hematotoxic effects on common carp, indicating that their use in treating fish infected with Aeromonas spp. could be considered. Hematological values remained within reference ranges, with only minor decreases in blood hemoglobin and mean corpuscular hemoglobin concentration observed in groups exposed to TC and TO.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Barbara Kot, Malgorzata Piechota, Andrzej Jakubczak, Magdalena Gryzinska, Malgorzata Witeska, Agata Gruzewska, Katarzyna Baran, Paulina Denkiewicz
Summary: This study investigated the presence of virulence genes and genetic relationships among MRSA isolates obtained from hospitalized patients. The results showed that certain genes encoding binding proteins and toxins were common, while different spa types exhibited varying distribution patterns.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Arshyn Muratkyzy Tlenshieva, Malgorzata Witeska, Tamara Minazhevna Shalakhmetova
Summary: This study evaluated the genotoxic, histological, and hematological effects of water pollution on grass carp in the Ili river. The concentration of heavy metals in the water gradually increased from one site to another, resulting in DNA and liver damage, as well as gill lesions in the fish. The assessment of genotoxicity using comet analysis and liver histology was the most sensitive, while differential leukocyte count was the least useful indicator of water contamination.
ENVIRONMENTAL POLLUTANTS AND BIOAVAILABILITY
(2022)
Article
Multidisciplinary Sciences
Barbara Kot, Malgorzata Piechota, Piotr Szweda, Joanna Mitrus, Jolanta Wicha, Agata Gruzewska, Malgorzata Witeska
Summary: The study investigated the presence of virulence genes and antibiotic resistance in 109 KP isolates from hospitalized patients. The majority of the isolates (68.8%) were multi-drug resistant (MDR), and 59.6% produced extended-spectrum beta-lactamases (ESBLs). Metallo-beta-lactamases (MBLs) were produced by 22% of isolates, with 16.5% producing New Delhi metallo-beta-lactamase (NDM-1). Genes encoding adhesins, enterobactin, and yersiniabactin were frequently identified, while genes encoding salmochelin and colibactin were rare. Several genes associated with capsule production and hypermucoviscosity were detected in a small percentage of isolates. The study also found that a significant proportion of hypervirulent KP (hvKP) isolates were MDR and produced ESBLs, posing a serious threat to healthcare systems.
SCIENTIFIC REPORTS
(2023)
Review
Agriculture, Dairy & Animal Science
Malgorzata Witeska, Elzbieta Kondera, Bartosz Bojarski
Summary: Hematological analysis is a commonly used method to assess the physiological state of fish, and it includes various parameters related to blood cells and thrombocytes. It is an important tool in evaluating the impact of substances on fish in ecotoxicology and pharmacotoxicology, together with biochemical and histopathological analyses. The advantages of hematological analysis include its simplicity and cost-effectiveness, while the limitations lie in the requirement of experienced personnel. There is a need for more research on the effects of xenobiotics on the cellular structure of fish head kidney hematopoietic tissue, and we recommend conducting research using both hematological and hematopoietic analysis to assess the impact of toxic substances on fish.
