Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients

Fibrin exposure triggers αIIbβ3‐independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge‐dependent manner

(2020) Samantha J. Montague et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanisms of receptor shedding in platelets

(2018) Samantha J. Montague et al.   BLOOD

Platelet dysfunction during trauma involves diverse signaling pathways and an inhibitory activity in patient-derived plasma

(2018) Christopher C. Verni et al.   Journal of Trauma and Acute Care Surgery

Impact of blood products on platelet function in patients with traumatic injuries: a translational study

(2017) Hanne Hee Henriksen et al.   JOURNAL OF SURGICAL RESEARCH

Soluble fibrin causes an acquired platelet glycoprotein VI signaling defect: implications for coagulopathy

(2017) M. Y. Lee et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet transfusions reduce fibrinolysis but do not restore platelet function during trauma hemorrhage

(2017) Paul Vulliamy et al.   Journal of Trauma and Acute Care Surgery

Platelet transfusions reduce fibrinolysis but do not restore platelet function during trauma hemorrhage

(2017) Paul Vulliamy et al.   Journal of Trauma and Acute Care Surgery

Advances in the understanding of trauma-induced coagulopathy

(2016) R. Chang et al.   BLOOD

Longitudinal changes in hemostatic parameters and reduced pulsatility contribute to non-surgical bleeding in patients with centrifugal continuous-flow left ventricular assist devices

(2016) Kavitha Muthiah et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

GPVI modulation during platelet activation and storage: its expression levels and ectodomain shedding compared to markers of platelet storage lesion

(2016) Ehteramolsadat Hosseini et al.   PLATELETS

Assessing the Methodology for Calculating Platelet Contribution to Clot Strength (Platelet Component) in Thromboelastometry and Thrombelastography

(2015) Cristina Solomon et al.   ANESTHESIA AND ANALGESIA

Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma

(2015) John B. Holcomb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Microfluidics and Coagulation Biology

(2013) Thomas V. Colace et al.   Annual Review of Biomedical Engineering

O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions

(2012) A. A. Nowak et al.   BLOOD

The incidence and magnitude of fibrinolytic activation in trauma patients

(2012) I. RAZA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Characterization of platelet dysfunction after trauma

(2012) Matthew E. Kutcher et al.   Journal of Trauma and Acute Care Surgery

Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa

(2011) M. Al-Tamimi et al.   BLOOD

Functional definition and characterization of acute traumatic coagulopathy

(2011) Ross Davenport et al.   CRITICAL CARE MEDICINE

Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing

(2011) Melissa V. Chan et al.   PLATELETS

Nerve Growth Factor Inhibits Metalloproteinase-Disintegrins and Blocks Ectodomain Shedding of Platelet Glycoprotein VI

(2010) Lakshmi C. Wijeyewickrema et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations

(2010) D. FRITH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Measuring soluble platelet glycoprotein VI in human plasma by ELISA

(2009) Mohammad Al-Tamimi et al.   PLATELETS