Article
Endocrinology & Metabolism
Sadam Ahmed Elayah, Hamza Younis, Hao Cui, Xiang Liang, Karim Ahmed Sakran, Baleegh Alkadasi, Essam Ahmed Al-Moraissi, Mohammed Albadani, Wafa Al-Okad, Junbo Tu, Sijia Na
Summary: This clinical trial aimed to assess the impact of autologous concentrated growth factor (CGF) as a socket-filling material and its ridge preservation properties following lower third molar extraction. The results showed that CGF sites had higher bone height and width, as well as significantly higher bone density compared to control sites. Therefore, the use of CGF by dentists during dental extractions may be encouraged, particularly when alveolar ridge preservation is required.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Pharmacology & Pharmacy
Sonia Trombino, Federica Curcio, Roberta Cassano, Manuela Curcio, Giuseppe Cirillo, Francesca Iemma
Summary: Cardiac regeneration aims to reconstruct the heart contractile mass and prevent functional deterioration by delivering pro-regenerative cells, drugs, or growth factors to the injury site. Biomaterials, including engineered hydrogels and polymeric nanoparticles, have shown promise in post-infarction therapy and tissue engineering for cardiovascular diseases. Italian research groups have made significant contributions in this field, focusing on natural and synthetic biomaterials, fabrication techniques, and the current status of clinical trials.
Article
Engineering, Chemical
Manali Somani, Samrat Mukhopadhyay, Bhuvanesh Gupta
Summary: Polyurethane (PU) is a promising polymeric material for biomedical applications due to its exceptional physicochemical properties. However, the immune response and infections caused by PU-based implants are unavoidable. Immobilizing bioactive agents and biopolymers is an effective strategy to overcome these issues, but the inertness and hydrophobicity of PU hinder the immobilization process.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Materials Science, Coatings & Films
Ilya A. Morozov, Alexander S. Kamenetskikh, Anton Y. Beliaev, Roman I. Izumov, Mikhail Bannikov, Marina G. Scherban, Dmitriy M. Kiselkov
Summary: Modification of polymeric surface by plasma ions has the potential to create flexible functional materials, but the deformation behavior is crucial to consider for maintaining fracture resistance; deposition of carbon ions on the surface can enhance wettability and local mechanical properties, but the nonuniformities may constrain crack propagation.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Chemistry, Physical
Yue Lin, Xianzhi Hu, Futing Zi, Shuliang Chen, Yunlong Chen, Peng Yang, Yan Zhang, Xinrong Li
Summary: This study focused on the pre-treatment of gold tailings with ammonium bifluoride to enhance the extraction of remaining gold. The results demonstrated that ammonium bifluoride interacted with silica-bearing minerals in the tailings, resulting in a rougher surface and more cracks, facilitating the dissolution of occluded gold. Under the optimized conditions, the gold extraction efficiency increased by 48.45%.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Mohammad Irani, Sina Mohammadrezaei Nodeh
Summary: This study investigates the capability of composite and core-shell nanofibers for targeted delivery of anticancer drugs in lung cancer treatment. The results demonstrate that the simultaneous loading of CMPT and PTX anticancer drugs and Au nanoparticles in core-shell nanofibers is more beneficial for lung cancer treatment.
Article
Materials Science, Ceramics
Kourosh Fani, Mohammad Reza Farahpour, Zohreh Ghazi Tabatabaei
Summary: This study characterized and applied a scaffold containing chitosan, alginate, selenium and graphene nano-oxide (CAHG-Se) for bone regeneration. The results showed that the introduction of selenium and graphene nano-oxide significantly improved the water absorption, retention, and mechanical properties of the scaffold. In a rabbit model, the CAHG-Se scaffold significantly promoted bone defect regeneration compared to the control group.
CERAMICS INTERNATIONAL
(2022)
Review
Biochemistry & Molecular Biology
Michael V. Goltyaev, Elena G. Varlamova
Summary: The liver, as the largest gland in the body, plays a crucial role in regulating physiological processes. Nanomedicine using nanoparticles, especially selenium nanoparticles, has gained popularity in the treatment and diagnosis of liver diseases due to their environmentally safe, low-cost, simple, and high-performance properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Cell Biology
Jing-lin Wang, Hao-ran Ding, Chen-yan Pan, Xiao-lei Shi, Hao-zhen Ren
Summary: Hepatectomy is effective for liver diseases, but complications like post-hepatectomy liver failure (PHLF) threaten patients' lives. Liver transplantation is limited by donor shortage and high cost, so there is a need for new treatments. Mesenchymal stem cell (MSC) transplantation shows promise due to easy access and low immunogenicity.
CELL DEATH & DISEASE
(2021)
Article
Environmental Studies
Dalit Shach-Pinsly, Hadas Shadar
Summary: This article explores the transformation of rural towns from agricultural towns to settlements focused on the quality of rural life and scenic resources, threatened by densification and development. The tools outlined in this article aim to meet the need for rural renewal by maintaining the agricultural-rural character and attracting additional employment. The article emphasizes the examination of ideological rural settlements and the changes they have undergone.
Article
Food Science & Technology
Wenjian Yang, Gangliang Huang, Fang Chen, Hualiang Huang
Summary: Selenium is an essential trace element that plays an important role in enhancing immunity and anti-tumor activities. Organic selenium polysaccharides with high selenium content have become a major research focus. The future development and utilization of selenium polysaccharides in healthcare or medicine is of great significance.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Engineering, Environmental
Jinwei Zhong, Qingfei Zhang, Gaizhen Kuang, Jinglin Xia, Luoran Shang
Summary: In this study, novel multicomponent microspheres (MCMs) with co-encapsulation and spatiotemporal drug release capabilities were developed for post-surgical liver cancer treatment and liver regeneration. The MCMs, fabricated via a microfluidic platform, consisted of a sodium alginate shell and gelatin methacrylate cores. The unique particle-in-particle structure allowed for the loading of doxorubicin (DOX) into the shell and augmenter of liver regeneration (ALR) into the cores, enabling rapid release of DOX and more sustained release of ALR. The dual-drug-loaded MCMs showed promising effects in postsurgical tumor killing and promoting liver regeneration, indicating their potential as versatile drug delivery systems for post-surgical cancer therapy.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Regina M. Krohn, Vince Palace, Judit E. G. Smits
Summary: Metal accumulation in wood frog tadpoles varies greatly depending on the developmental stage surrounding metamorphic climax, with metabolic changes and intestinal remodeling needing to be considered.
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2021)
Article
Polymer Science
Izotz Amundarain, Rafael Miguel-Fernandez, Asier Asueta, Sara Garcia-Fernandez, Sixto Arnaiz
Summary: This study investigates the preparation and characteristics of rigid polyurethane foams (RPUFs) synthesized from polyols obtained by glycolysis of post-industrial waste RPUFs. The results show that the partial substitution of commercial polyols with recycled polyols increases the reactivity of the foaming process and improves the compressive properties and modulus values of the foams.
Review
Engineering, Environmental
Rangabhashiyam Selvasembian, Willis Gwenzi, Nhamo Chaukura, Siyanda Mthembu
Summary: The pollution of aquatic systems with harmful substances is a global challenge, and adsorption technique is considered as an effective means to address this issue. Polyurethane foam as an adsorbent has significant application potential, but further research is needed on its regeneration, recycling, and disposal aspects.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Yiheng Dai, Tianyu Li, Zhiheng Zhang, Yizheng Tan, Shuojiong Pan, Luo Zhang, Huaping Xu
Summary: This study demonstrates a novel oxidative polymerization reaction in cells triggered by intracellular ROS, selectively inducing apoptosis in cancer cells. The polymerization products disrupt intracellular antioxidant systems, leading to increased oxidative stress, further promoting oxidative polymerization and activating apoptosis pathways related to ROS. The anticancer efficacy and biosafety of this strategy are proven in vitro and in vivo, suggesting a new possibility for chemists to manipulate cellular behavior through artificial chemical reactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Materials Science, Biomaterials
Chenxing Sun, Shiqian Gao, Yizheng Tan, Zhiheng Zhang, Huaping Xu
Summary: The designed and prepared ROS-responsive side-chain selenium-grafted polymers show potential antiangiogenic activity, which can be used to load photodynamic therapeutic agents and chemotherapeutic drugs to inhibit angiogenesis and relieve hypoxia.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Engineering, Biomedical
Shuojiong Pan, Tianyu Li, Yizheng Tan, Huaping Xu
Summary: In this study, selenium-containing nanoparticles were constructed to synergistically enhance Pem-based chemotherapy and NK cell-based immunotherapy. The selenium compounds could deliver Pem to tumor sites and improve the chemotherapy efficiency. Additionally, they can also activate NK cell's immune response. The in vitro and in vivo experiments revealed the potential mechanism, highlighting the promising prospect of this strategy in chemoimmunotherapy.
Article
Chemistry, Multidisciplinary
Chaowei He, Muqing Cao, Jianbing Liu, Zhuoxin Ge, Ruihao Zhou, Huaping Xu
Summary: Modern Olympics have increasingly utilized nanotechnologies to support athletes and enhance sports performance. Nanoscience is applied in ice skating, wearable monitoring devices, skiing sports equipment, winter protection, and Olympic printing, playing a significant role in the Olympic and Paralympic Winter Games.
Article
Polymer Science
Muqing Cao, Peng Zhao, Cheng Liu, Jiahao Xia, Huaping Xu
Summary: Dynamic covalent bonds in polymeric materials show synergistic effects and can enhance their dynamic properties.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Peng Zhao, Muqing Cao, Cheng Liu, Yiheng Dai, Yizheng Tan, Shaobo Ji, Huaping Xu
Summary: This study developed underwater remote stimulus-responsive self-healing polymer materials using visible-light-responsive diselenide bonds as healing moieties. The material achieved excellent underwater transmission capability and showed rapid healing efficiency above 90% with strain recovery of nearly 200% in 5 minutes.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Chengfei Liu, Banruo Xianyu, Yiheng Dai, Shuojiong Pan, Tianyu Li, Huaping Xu
Summary: Polymerization inside living cells provides chemists with a multitude of possibilities to modulate cell activities. We reported a hyperbranched polymerization in living cells based on the oxidative polymerization of organotellurides and intracellular redox environment. The obtained hyperbranched polymer aggregated into branched nanostructures in cells, which could effectively evade drug pumps and decrease drug efflux, ensuring the polymerization for persistent treatment.
Article
Chemistry, Multidisciplinary
Shuojiong Pan, Jun Guan, Banruo Xianyu, Yizheng Tan, Tianyu Li, Huaping Xu
Summary: Self-assembled selenium-containing nanoparticles are developed to reverse NK cell exhaustion and enhance NK-cell-mediated immunotherapy, effectively inhibiting tumor growth.
ADVANCED MATERIALS
(2023)
Review
Polymer Science
Yiheng Dai, Jun Guan, Shenghan Zhang, Shuojiong Pan, Banruo Xianyu, Zhuoxin Ge, Jinyan Si, Chaowei He, Huaping Xu
Summary: Significant progress has been made in the field of tellurium-containing polymers in recent decades. These polymers exhibit unique properties and have promising applications. This review provides an overview of the diversification of tellurium-containing polymers and their synthetic methods, as well as a detailed discussion of their properties and applications in various fields. By summarizing the recent developments and trends, this review aims to popularize the concepts and serve as a comprehensive handbook for researchers in the field of chemistry and materials.
PROGRESS IN POLYMER SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Chengfei Liu, Jinyan Si, Muqing Cao, Peng Zhao, Yiheng Dai, Huaping Xu
Summary: Visualizing polymer chain growth is always a hot topic in polymer chemistry. However, current characterization methods are limited in their ability to differentiate the degree of polymerization without isolating the samples from the reaction vessel, let alone to detect insoluble polymers. This study establishes a reliable relationship between polymer chain growth and fluorescence properties through polymerization induced emission, enabling real-time monitoring of the polymerization reaction. The method can also be applied to observe the polymerization process of insoluble polymers, opening a new avenue for visualizing polymer chain growth in real-time, regardless of polymer solubility.
Article
Multidisciplinary Sciences
Ningyue Chen, Shuwei Li, Peng Zhao, Ran Liu, Yu Xie, Jin-Liang Lin, Christian A. Nijhuis, Bingqian Xu, Liang Zhang, Huaping Xu, Yuan Li
Summary: This study introduces a method to form stable gold-based self-assembled monolayers (SAMs) using selenide anchoring groups, resulting in highly stable molecular tunnel junctions. The findings demonstrate the potential application of selenide-derived stable SAMs in long-lived molecular electronic devices.
Review
Chemistry, Multidisciplinary
Muqing Cao, Yizheng Tan, Huaping Xu
Summary: In recent years, there has been extensive research and development on the mechanochemistry of polymers, specifically the reactivity of polymers under mechanical stimuli. More attention has been given to dynamic chalcogen-containing polymers due to their sensitive responsiveness and precise biofunction. This perspective provides an overview of mechanochemistry in dynamic chalcogen-containing polymers, covering fundamental mechanochemistry and applications. It focuses on mechanically induced color/fluorescence changes, drug release, and material strengthening and toughening of functional mechano-responsive polymeric materials. Additionally, currently unsolved issues, challenges, and potential opportunities for the future are summarized and discussed.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Banruo Xianyu, Shuojiong Pan, Shiqian Gao, Huaping Xu, Tianyu Li
Summary: This study developed a selenium-containing nanocomplex that can act as a dual immune checkpoint inhibitor in cancer immunotherapy. The nanocomplex targets PD-L1 and HLA-E on tumor cells to block immune checkpoints, promoting NK cell-mediated antitumoral activity.
Article
Nanoscience & Nanotechnology
Peng Zhao, Muqing Cao, Cheng Liu, Yiheng Dai, Yizheng Tan, Shaobo Ji, Huaping Xu
Summary: In this study, a remote self-healing underwater elastomer material was developed using visible-light-responsive diselenide bonds. The material exhibited excellent underwater transmission capability and fast healing speed, with a strain at break of up to 200% in 5 minutes and almost full recovery of toughness within 1 hour. This provides a new direction for underwater pipeline sealing applications.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Luo Zhang, Yiheng Dai, Shuojiong Pan, Yizheng Tan, Chenxing Sun, Muqing Cao, Huaping Xu
Summary: Researchers have developed copper-selenocysteine quantum dots (Cu-Sec QDs) using a facile and robust thermal titration process. These QDs exhibit strong photothermal enhancement of Fenton-like reaction and cytotoxicity, showing great potential for cancer treatment.
ACS APPLIED BIO MATERIALS
(2022)
