☆ 4.5 Editorial Material

Prioritisation of the human papillomavirus vaccine in a time of constrained supply

LANCET CHILD & ADOLESCENT HEALTH (2020)

Journal

LANCET CHILD & ADOLESCENT HEALTH

Volume 4, Issue 5, Pages 349-351

Publisher

ELSEVIER SCI LTD

DOI: 10.1016/S2352-4642(20)30038-9

Keywords

-

Categories

Pediatrics

Funding

NATIONAL CANCER INSTITUTE [ZIACP010217] Funding Source: NIH RePORTER
World Health Organization [001] Funding Source: Medline

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Article Immunology

Low Uptake of the Second Dose of Human Papillomavirus Vaccine in Dar es Salaam, Tanzania

Nchang'wa Nhumba, Bruno Sunguya

Summary: Cervical cancer is a major health issue in Tanzania, and the HPV vaccine is an effective intervention. However, the uptake of the second dose of the vaccine is low, with factors such as age, attitude, and awareness influencing the uptake.

VACCINES (2022)

Add to Collection

Article Infectious Diseases

Prevalence of cervicovaginal human papillomavirus infection and genotypes in the pre-vaccine era in China: A nationwide population-based study

He-Ling Bao, Cheng Jin, Shi Wang, Yi Song, Zhou-Yang Xu, Xiao-Jin Yan, Li-Ming Li, Yi Ning, Hai-Jun Wang

Summary: In the pre-vaccine era in China, the HPV prevalence was 15.0%, with high-risk and low-risk genotypes at 12.1% and 5.2% respectively. The prevalence of vaccine-related HPV genotypes were 2.1%, 2.4%, and 8.3% for bivalent, quadrivalent, and nonavalent vaccines, while non-vaccine high-risk genotypes were at 5.7%. HPV genotype infection varied significantly across different age groups and geographic locations.

JOURNAL OF INFECTION (2021)

Add to Collection

Article Immunology

Human Papillomavirus Vaccines

Lauri E. Markowitz, John T. Schiller

Summary: HPV vaccines are highly effective in preventing HPV-attributable cancers and have been introduced into national immunization programs in over 100 countries. The success of these vaccines has sparked interest in ambitious disease reduction goals.

JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

Safety of 4-valent human papillomavirus vaccine in males: a large observational post-marketing study

Kandace L. Amend, Bruce Turnbull, Li Zhou, Morgan A. Marks, Christine Velicer, Patricia Saddier, John D. Seeger

Summary: This study assesses the safety of the 4-valent HPV vaccine in males and finds associations with same-day allergic reactions, ear infections, intracranial injury, cellulitis, and concussion. However, other adverse outcomes are determined to be more likely related to activities common in adolescent males rather than the vaccination itself.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2022)

Add to Collection

Article Virology

Head-to-head comparison of genotyping of human papillomavirus by real-time multiplex PCR assay using type-specific primers and SPF10-PCR-based line probe assay

Jian Yin, Siying Peng, Changning Zhang, Xinyue Li, Fangfang Hu, Wen Chen, Youlin Qiao

Summary: The performance of LiPA-25 and Hybribio-23 in HPV detection and genotyping was compared. The results showed that the two methods had similar outcomes, suggesting that Hybribio-23 can be used for HPV detection and genotyping in epidemiological and vaccine studies worldwide.

JOURNAL OF MEDICAL VIROLOGY (2023)

Add to Collection

Article Immunology

Incident autoimmune conditions among males receiving quadrivalent human papillomavirus vaccine in the United States

John D. Seeger, Kandace L. Amend, Bruce R. Turnbull, Li Zhou, Morgan A. Marks, Christine Velicer, Patricia Saddier

Summary: This study assessed the risk of new onset autoimmune conditions among males receiving the 4-valent human papillomavirus (HPV) vaccine (4vHPV), and the results showed that the incidence of autoimmune conditions among vaccinated males was similar to that among unvaccinated males.

VACCINE (2023)

Add to Collection

Article Immunology

Tanzania's human papillomavirus (HPV) vaccination program: Community awareness, feasibility, and acceptability of a national HPV vaccination program, 2019

Anyie J. Li, Fatuma Manzi, Furaha Kyesi, Yusuf Makame, William Mwengee, Monica Fleming, Abdallah Mkopi, Selemani Mmbaga, Dafrossa Lyimo, Anagha Loharikar

Summary: The HPV vaccination program in Tanzania was well accepted by community stakeholders in 18 councils, with adequate knowledge demonstrated by health workers and school personnel. However, continued technical support for integrating the vaccine into routine immunization activities and reinforcing basic knowledge about the vaccine in specific community groups is needed.

VACCINE (2022)

Add to Collection

Review Biotechnology & Applied Microbiology

Human papillomavirus vaccine effectiveness by age at vaccination: A systematic review

Mallory K. Ellingson, Hassan Sheikha, Kate Nyhan, Carlos R. Oliveira, Linda M. Niccolai

Summary: Human papillomavirus (HPV) vaccines are most effective when administered at younger ages, preventing infections prior to natural exposure. A systematic review of HPV vaccine effectiveness studies published between 2007 and 2022 found that the highest vaccine effectiveness was observed in the youngest age group. Vaccine effectiveness estimates ranged from approximately 74% to 93% for younger adolescents ages 9-14 years and from 12% to 90% for adolescents ages 15-18 years. These findings emphasize the importance of on-time vaccination for optimal protection against HPV-related diseases.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2023)

Add to Collection

Article Obstetrics & Gynecology

Human papillomavirus vaccine effectiveness within a cervical cancer screening programme: cohort study

C. Acuti Martellucci, S. Nomura, D. Yoneoka, P. Ueda, J. M. L. Brotherton, K. Canfell, M. Palmer, L. Manzoli, P. Giorgi Rossi, A. De Togni, C. Palmonari, A. Califano, E. Saito, M. Hashizume, K. Shibuya

Summary: This retrospective cohort study in Italy assessed the effectiveness of an HPV vaccination programme in reducing the risk of cervical abnormalities detected during subsequent screenings. Results showed that women who received at least one dose of the HPV vaccine were significantly less likely to have abnormal cervical cytology. Overall, catch-up HPV vaccination almost halved the risk of cytological abnormalities in organized cervical screening programmes.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Sexual behaviour, human papillomavirus and its vaccine: a qualitative study of adolescents and parents in Andalusia

Maria Gonzalez-Cano, Francisco Garrido-Pena, Eugenia Gil-Garcia, Marta Lima-Serrano, Maria Dolores Cano-Caballero

Summary: The study found a lack of communication between adolescents and parents regarding sexual behavior, as well as scarce knowledge about HPV and vaccination in both groups. Parents mistrust vaccination due to a lack of qualified and verified information about its benefits.

BMC PUBLIC HEALTH (2021)

Add to Collection

Article Medicine, General & Internal

Efficacy of Human Papillomavirus Vaccines for Recalcitrant Anogenital and Oral Warts

Giulia Ciccarese, Astrid Herzum, Gaetano Serviddio, Corrado Occella, Aurora Parodi, Francesco Drago

Summary: HPV vaccines may have a therapeutic role in addition to standard treatments for anogenital warts and oral warts, especially for persistent lesions.

JOURNAL OF CLINICAL MEDICINE (2023)

Add to Collection

Article Immunology

National introduction of human papillomavirus (HPV) vaccine in Tanzania: Programmatic decision-making and implementation

Alex Mphuru, Anyie J. Li, Furaha Kyesi, William Mwengee, Fikiri Mazige, Raphael Nshunju, Berrington Shayo, Mary Rose Giattas, Anagha Loharikar, Dafrossa Lyimo

Summary: This study highlights Tanzania's efforts in preventing cervical cancer, including the introduction of HPV vaccines and the accomplishment of most of the planned vaccination. The work involved collaboration between government departments, the World Health Organization, and other partners, with training and meetings conducted at various levels for advocacy and promotion. While the coverage for the first dose of the vaccine is relatively high, efforts are still needed to improve the uptake of the second dose.

VACCINE (2022)

Add to Collection

Article Immunology

Cost of human papillomavirus vaccine delivery in a single-age cohort, routine-based vaccination program in Senegal

Timothy Brennan, Anna Hidle, Reena H. Doshi, Qian An, Anagha Loharikar, Rebecca Casey, Ousseynou Badiane, Alassane Ndiaye, Aliou Diallo, Jerlie Loko Roka, Nelly Mejia, Taiwo Abimbola

Summary: This study evaluated the costs of Senegal's introduction of HPV vaccine. The total financial and economic delivery costs were found to be $1,152,351 and $2,838,466, respectively. A total of 375,608 HPV vaccine doses were administered during the cost evaluation.

VACCINE (2022)

Add to Collection

Review Immunology

Immunogenicity, efficacy, and safety of human papillomavirus vaccine: Data from China

Mingzhu Li, Chao Zhao, Yun Zhao, Jingran Li, Lihui Wei

Summary: The incidence rate and mortality rate of cervical cancer have been increasing among young women in China. To address this, it is crucial to improve HPV vaccination rates, especially among the younger population. China currently offers five types of HPV vaccines, all of which have undergone clinical trials and have been proven to be safe, effective, and immunogenic in preventing persistent HPV infections and genital precancerous lesions. However, the low vaccination rate in China calls for increased efforts to reduce the incidence and mortality rates of cervical cancer.

FRONTIERS IN IMMUNOLOGY (2023)

Add to Collection

Article Public, Environmental & Occupational Health

Impact assessment of a provider-targeted national vaccine messaging campaign on human papillomavirus vaccination rates among US adolescent males

Denny Fe Agana-Norman, Abbey B. Berenson, Mihyun Chang

Summary: The uptake of the HPV vaccine in the US was initially low, especially among adolescent males. To address this issue, the CDC partnered with a communications development company to launch a national campaign. Research shows that this campaign had a positive impact on improving HPV vaccine uptake among adolescent males.

PREVENTIVE MEDICINE (2022)

Add to Collection

Editorial Material Medicine, General & Internal

Price transparency is a step towards sustainable access in middle income countries

Tania Cernuschi, Shawn Gilchrist, Adnan Hajizada, Melissa Malhame, Stephanie Mariat, Greg Widmyer

BMJ-BRITISH MEDICAL JOURNAL (2020)

Add to Collection

Article Infectious Diseases

Sexually transmitted infections among women randomised to depot medroxyprogesterone acetate, a copper intrauterine device or a levonorgestrel implant

Jennifer Deese, Neena Philip, Margaret Lind, Khatija Ahmed, Joanne Batting, Mags Beksinska, Vinodh A. Edward, Cheryl E. Louw, Maricianah Onono, Thesla Palanee-Phillips, Jennifer A. Smit, Jared M. Baeten, Deborah Donnell, Timothy D. Mastro, Nelly R. Mugo, Kavita Nanda, Helen Rees, Charles Morrison

Summary: Research suggests that the risk of chlamydia and gonorrhoea may vary with contraceptive method use, with further investigation needed to better understand the mechanisms of susceptibility to these infections in the context of contraceptive use.

SEXUALLY TRANSMITTED INFECTIONS (2021)

Add to Collection

Article Immunology

Incidence of Herpes Simplex Virus Type 2 Infection Among African Women Using Depot Medroxyprogesterone Acetate, a Copper Intrauterine Device, or a Levonorgestrel Implant for Contraception: A Nested Randomized Trial

Nelly R. Mugo, Randy M. Stalter, Renee Heffron, Helen Rees, Caitlin W. Scoville, Charles Morrison, Athena P. Kourtis, Elizabeth Bukusi, Mags Beksinka, Neena M. Philip, Ivana Beesham, Jen Deese, Vinodh Edward, Deborah Donnell, Jared M. Baeten

Summary: This study found no association between HSV-2 acquisition and the use of three contraceptive methods through a randomized trial. Previous observational studies have suggested a possible association between the use of intramuscular depot medroxyprogesterone acetate (DMPA-IM) and HSV-2 acquisition.

CLINICAL INFECTIOUS DISEASES (2022)

Add to Collection

Editorial Material Immunology

Building the concept for WHO Evidence Considerations for Vaccine Policy (ECVP): Tuberculosis vaccines intended for adults and adolescents as a test case

Sonali Kochhar, Draurio Barreira, Pauline Beattie, Marco Cavaleri, Alejandro Cravioto, Mike W. Frick, Ann M. Ginsberg, Ian Hudson, David C. Kaslow, Sherry Kurtz, Christian Lienhardt, Shabir A. Madhi, Christopher Morgan, Yalda Momeni, Deepali Patel, Helen Rees, Taryn Rogalski-Salter, Alexander Schmidt, Boitumelo Semete-Makokotlela, Gerald Voss, Richard G. White, Matteo Zignol, Birgitte Giersing

Summary: Currently, there is a lack of formal mechanisms or systematic approaches to provide vaccine developers with anticipated evidence to support global policy recommendations. To address this issue, the World Health Organization (WHO) is evaluating a new strategic alignment tool called Evidence Considerations for Vaccine Policy (ECVP). The aim of ECVPs is to bridge the gap in evidence needs and reduce the risk of delays between vaccine recommendation and use.

VACCINE (2022)

Add to Collection

Article Immunology

Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition - A Nested Case-Control Study in HIV-1 Serodiscordant Couples

Melinda S. Suchard, Neil Martinson, Susan Malfeld, Debbie de Assis Rosa, Romel D. Mackelprang, Jairam Lingappa, Xuanlin Hou, Helen Rees, Sinead Delany-Moretlwe, Hadassa Goldfein, Heena Ranchod, David Coetzee, Kennedy Otwombe, Lynn Morris, Caroline T. Tiemessen, Dana M. Savulescu

Summary: This study found that the presence of HLA antibodies in highly exposed persistently seronegative individuals was associated with reduced odds of HIV acquisition. These findings may have important implications for the development of HIV vaccines and treatment strategies.

FRONTIERS IN IMMUNOLOGY (2022)

Add to Collection

Review Obstetrics & Gynecology

Increasing global temperatures threaten gains in maternal and newborn health in Africa: A review of impacts and an adaptation framework

Matthew F. Chersich, Fiona Scorgie, Veronique Filippi, Stanley Luchters

Summary: Anatomical, physiologic, and socio-cultural changes during pregnancy and childbirth increase vulnerability to high ambient temperatures in women and newborns. This can lead to various clinical consequences. To adapt to this situation, behavioral changes, health system interventions, building modifications, and climate financing are proposed.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2023)

Add to Collection

Article Multidisciplinary Sciences

High HIV incidence among young women in South Africa: Data from a large prospective study

Thesla Palanee-Phillips, Helen Rees, Kate B. Heller, Khatija Ahmed, Joanne Batting, Ivana Beesham, Renee Heffron, Jessica Justman, Heeran Makkan, Timothy D. Mastro, Susan A. Morrison, Nelly Mugo, Gonasagrie Nair, James Kiarie, Neena M. Philip, Melanie Pleaner, Krishnaveni Reddy, Pearl Selepe, Petrus S. Steyn, Caitlin W. Scoville, Jenni Smit, Katherine K. Thomas, Deborah Donnell, Jared M. Baeten

Summary: The HIV incidence is high among South African women seeking contraceptive services, with age, sexually transmitted infections, BMI, and number of sexual partners being factors associated with HIV acquisition. To mitigate the ongoing risk of HIV acquisition for this vulnerable population, the integration of diagnostic management of sexually transmitted infections and delivery of HIV prevention options is needed.

PLOS ONE (2022)

Add to Collection

Article Oncology

Public health opportunities resulting from sufficient HPV vaccine supply and a single-dose vaccination schedule

Aimee R. Kreimer, Tania Cernuschi, Helen Rees, Julia M. L. Brotherton, Carolina Porras, John Schiller

Summary: Many countries burdened by cervical cancer have not provided HPV vaccines to most eligible girls, resulting in limited access to screening and treatment. However, the increased vaccine supply and single-dose recommendation provide an opportunity to expand vaccination and prevent millions of projected cervical cancer cases.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2023)

Add to Collection

Article Multidisciplinary Sciences

A multinational Delphi consensus to end the COVID-19 public health threat

Jeffrey Lazarus, Diana Romero, Christopher J. Kopka, Salim Abdool Karim, Laith J. Abu-Raddad, Gisele Almeida, Ricardo Baptista-Leite, Joshua A. Barocas, Mauricio L. Barreto, Yaneer Bar-Yam, Quique Bassat, Carolina Batista, Morgan Bazilian, Shu-Ti Chiou, Carlos del Rio, Gregory J. Dore, George F. Gao, Lawrence O. Gostin, Margaret Hellard, Jose L. Jimenez, Gagandeep Kang, Nancy Lee, Mojca Maticic, Martin McKee, Sabin Nsanzimana, Miquel Oliu-Barton, Bary Pradelski, Oksana Pyzik, Kenneth Rabin, Sunil Raina, Sabina Faiz Rashid, Magdalena Rathe, Rocio Saenz, Sudhvir Singh, Malene Trock-Hempler, Sonia Villapol, Peiling Yap, Agnes Binagwaho, Adeeba Kamarulzaman, Ayman El-Mohandes

Summary: Despite scientific and medical advances, political, socioeconomic, and behavioral factors continue to undermine the response to the COVID-19 pandemic. A Delphi study involving a diverse panel of experts from 112 countries and territories developed a set of recommendations across various domains to address this global threat to public health.

NATURE (2022)

Add to Collection

Article Immunology

No woman left behind: achieving cervical cancer elimination among women living with HIV

Kirthana Sharma, Dorothy A. Machalek, Zheng Q. Toh, Demisew Amenu, Mazvita Muchengeti, Andrew K. Ndlovu, Alex Mremi, Bariki Mchome, Andrew J. Vallely, Lynette Denny, Helen Rees, Suzanne M. Garland

Summary: Cervical cancer is a major concern for women globally, particularly in low-income and middle-income countries and among women with HIV. Eliminating cervical cancer among women with HIV requires addressing both biological and social factors. There is a lack of research and evidence on cervical cancer elimination in this population, particularly in terms of HPV vaccination and its long-term effectiveness. Social and structural factors such as poverty, stigma, and gender discrimination pose challenges to the elimination strategy for cervical cancer.

LANCET HIV (2023)

Add to Collection

Article Public, Environmental & Occupational Health

COVID-19 vaccination rollout in the World Health Organization African region: status at end June 2022 and way forward

Benido Impouma, Franck Mboussou, Bridget Farham, Lindiwe Makubalo, Kasonde Mwinga, Adelheid Onyango, Lisa Sthreshley, Kalu Akpaka, Thierno Balde, Phionah Atuhebwe, Abdou Salam Gueye, Felicitas Zawaira, Helen Rees, Joseph Cabore, Matshidiso Moeti

Summary: By the end of June 2022, two countries in the WHO African region have achieved the vaccination targets set by WHO, and seven countries are on track. Additionally, some countries have made significant progress in increasing their vaccination rates in a short period of time. However, the African region still has the lowest vaccination rate globally and efforts need to continue to improve the vaccination coverage.

EPIDEMIOLOGY AND INFECTION (2022)

Add to Collection

Article Medicine, General & Internal

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

Summary: This study presents the final results of the Solidarity trial and meta-analyses of mortality in relevant trials. The findings suggest that remdesivir does not have a significant effect on COVID-19 patients who are already on ventilators. However, it does have a small effect against death or progression to ventilation in other hospitalized patients.

LANCET (2022)

Add to Collection

Letter Medicine, General & Internal

Booster vaccines for COVID-19 vaccine breakthrough cases? Authors' reply

Philip R. Krause, Helen Rees, J. Peter Figueroa, Soumya Swaminathan, Ana Maria Henao Restrepo

LANCET (2022)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.