Integrated Genomic Analysis of Chromosomal Alterations and Mutations in B-Cell Acute Lymphoblastic Leukemia Reveals Distinct Genetic Profiles at Relapse

IKZF1 alterations in acute lymphoblastic leukemia: The good, the bad and the ugly

(2020) Stephanie Vairy et al.   BLOOD REVIEWS

Acute lymphoblastic leukaemia

(2020) Florent Malard et al.   LANCET

Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia

(2019) Salih Demir et al.   HAEMATOLOGICA

Chromosomal microarray analysis is superior in identifying cryptic aberrations in patients with acute lymphoblastic leukemia at diagnosis/relapse as a single assay

(2019) Chuanfei Chen et al.   International Journal of Laboratory Hematology

Next-Generation Sequencing in Acute Lymphoblastic Leukemia

(2019) Nicoletta Coccaro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia

(2019) Benshang Li et al.   BLOOD

IKZF1 deletions in pediatric acute lymphoblastic leukemia: still a poor prognostic marker?

(2019) Martin Stanulla et al.   BLOOD

TP53 alterations in relapsed childhood acute lymphoblastic leukemia

(2019) Chih‐Hsiang Yu et al.   CANCER SCIENCE

Intensifying Treatment of Childhood B-Lymphoblastic Leukemia With IKZF1 Deletion Reduces Relapse and Improves Overall Survival: Results of Malaysia-Singapore ALL 2010 Study

(2018) Allen Eng Juh Yeoh et al.   JOURNAL OF CLINICAL ONCOLOGY

Intensified treatment for IKZF1-deleted childhood leukaemia

(2018) Talha Khan Burki   LANCET ONCOLOGY

Panel-based next-generation sequencing identifies prognostic and actionable genes in childhood acute lymphoblastic leukemia and is suitable for clinical sequencing

(2018) Hisashi Ishida et al.   ANNALS OF HEMATOLOGY

Copy number profiling of adult relapsed B-cell precursor acute lymphoblastic leukemia reveals potential leukemia progression mechanisms

(2017) Jordi Ribera et al.   GENES CHROMOSOMES & CANCER

Genome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome

(2016) Maribel Forero-Castro et al.   PLoS One

Genomics in acute lymphoblastic leukaemia: insights and treatment implications

(2015) Kathryn G. Roberts et al.   Nature Reviews Clinical Oncology

Biology of Childhood Acute Lymphoblastic Leukemia

(2015) Deepa Bhojwani et al.   PEDIATRIC CLINICS OF NORTH AMERICA

A Low Frequency of Losses in 11q Chromosome Is Associated with Better Outcome and Lower Rate of Genomic Mutations in Patients with Chronic Lymphocytic Leukemia

(2015) José Ángel Hernández et al.   PLoS One

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

(2014) Bernard Leroy et al.   HUMAN MUTATION

The Biology of Relapsed Acute Lymphoblastic Leukemia

(2014) Teena Bhatla et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Genomic Characterization of Acute Leukemias

(2014) Sabina Chiaretti et al.   MEDICAL PRINCIPLES AND PRACTICE

DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA

(2014) Sabina Chiaretti et al.   Mediterranean Journal of Hematology and Infectious Diseases

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation

(2013) Gro Nilsen et al.   BMC GENOMICS

Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia

(2013) A. Caye et al.   HAEMATOLOGICA

TP53 mutations are frequent in adult acute lymphoblastic leukemia cases negative for recurrent fusion genes and correlate with poor response to induction therapy

(2013) S. Chiaretti et al.   HAEMATOLOGICA

Robustness of Amplicon Deep Sequencing Underlines Its Utility in Clinical Applications

(2013) Vera Grossmann et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Acute lymphoblastic leukaemia

(2013) Hiroto Inaba et al.   LANCET

Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patients

(2013) S Weissmann et al.   LEUKEMIA

Advances in the Genetics of High-Risk Childhood B-Progenitor Acute Lymphoblastic Leukemia and Juvenile Myelomonocytic Leukemia: Implications for Therapy

(2012) M. L. Loh et al.   CLINICAL CANCER RESEARCH

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

(2012) P. Dorge et al.   HAEMATOLOGICA

Clonal evolution of acute leukemia genomes

(2012) M Jan et al.   ONCOGENE

Cytogenetic and Molecular Predictors of Outcome in Acute Lymphocytic Leukemia: Recent Developments

(2012) Ilaria Iacobucci et al.   Current Hematologic Malignancy Reports

Genomic profiling of B-progenitor acute lymphoblastic leukemia

(2011) Charles G. Mullighan   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Key pathways as therapeutic targets

(2011) C. J. Harrison   BLOOD

Mutations and Deletions of the TP53 Gene Predict Nonresponse to Treatment and Poor Outcome in First Relapse of Childhood Acute Lymphoblastic Leukemia

(2011) Jana Hof et al.   JOURNAL OF CLINICAL ONCOLOGY

Biology, Risk Stratification, and Therapy of Pediatric Acute Leukemias: An Update

(2011) Ching-Hon Pui et al.   JOURNAL OF CLINICAL ONCOLOGY

The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories

(2011) A Kohlmann et al.   LEUKEMIA

How new advances in genetic analysis are influencing the understanding and treatment of childhood acute leukemia

(2010) Kathryn G Roberts et al.   CURRENT OPINION IN PEDIATRICS

Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia

(2010) C. J. Schwab et al.   GENES CHROMOSOMES & CANCER

Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia

(2009) Charles G. Mullighan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

(2008) J. J. Yang et al.   BLOOD

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

(2008) Charles G. Mullighan et al.   NATURE

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE

Global Genomic Characterization of Acute Lymphoblastic Leukemia

(2008) Charles G. Mullighan et al.   SEMINARS IN HEMATOLOGY