Bioinformatic Analysis of 1000 Amphibian Antimicrobial Peptides Uncovers Multiple Length-Dependent Correlations for Peptide Design and Prediction

Evolutionary principles guiding amphibian conservation

(2020) Maciej Pabijan et al.   Evolutionary Applications

Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?

(2020) Marlon H. Cardoso et al.   Frontiers in Microbiology

Brevinin-1GHd: a novel Hylarana guentheri skin secretion-derived Brevinin-1 type peptide with antimicrobial and anticancer therapeutic potential

(2020) Yangyang Jiang et al.   BIOSCIENCE REPORTS

Cathelicidin-DM is an Antimicrobial Peptide from Duttaphrynus melanostictus and Has Wound-Healing Therapeutic Potential

(2020) Yaoqiang Shi et al.   ACS Omega

Two distinct amphipathic peptide antibiotics with systemic efficacy

(2020) Jayaram Lakshmaiah Narayana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly synergistic antimicrobial activity of magainin 2 and PGLa peptides is rooted in the formation of supramolecular complexes with lipids

(2020) Christopher Aisenbrey et al.   Scientific Reports

Targeting the fungal cell wall: current therapies and implications for development of alternative antifungal agents

(2019) Sahar Hasim et al.   Future Medicinal Chemistry

Antiviral peptides as promising therapeutic drugs

(2019) Liana Costa Pereira Vilas Boas et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Potential of Frog Skin Peptides for Anti-Infective Therapies: the Case of Esculentin-1a(1-21)NH2

(2019) Bruno Casciaro et al.   CURRENT MEDICINAL CHEMISTRY

Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens

(2019) Biswajit Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Antimicrobial Peptide Database provides a platform for decoding the design principles of naturally occurring antimicrobial peptides

(2019) Guangshun Wang   PROTEIN SCIENCE

Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues

(2019) Zhou et al.   Biomolecules

Peptidomic analysis in the discovery of therapeutically valuable peptides in amphibian skin secretions

(2019) J. Michael Conlon et al.   Expert Review of Proteomics

Dermaseptins, Multifunctional Antimicrobial Peptides: A Review of Their Pharmacology, Effectivity, Mechanism of Action, and Possible Future Directions

(2019) Emiel Jacob Henri Bartels et al.   Frontiers in Pharmacology

Insulinotropic, glucose-lowering, and beta-cell anti-apoptotic actions of peptides related to esculentin-1a(1-21).NH2

(2018) Vishal Musale et al.   AMINO ACIDS

The Amphibian Antimicrobial Peptide Temporin B Inhibits In Vitro Herpes Simplex Virus 1 Infection

(2018) M. E. Marcocci et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial, antifungal, anticancer activities and structural bioinformatics analysis of six naturally occurring temporins

(2018) Biswajit Mishra et al.   PEPTIDES

Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms

(2018) Evan F. Haney et al.   Scientific Reports

Novel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling

(2018) Qilin Long et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses

(2017) David J. Holthausen et al.   IMMUNITY

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

(2017) Célia Dos Santos et al.   PLoS One

Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators

(2017) Constantijn Raaymakers et al.   Nature Communications

Antimicrobial peptides and wound healing: biological and therapeutic considerations

(2016) Maria Luisa Mangoni et al.   EXPERIMENTAL DERMATOLOGY

Antimicrobial peptides from frog skin biodiversity and therapeutic promises

(2016) Ali Ladram   Frontiers in Bioscience-Landmark

Characteristics of cathelicidin-Bg, a novel gene expressed in the ear-side gland of Bufo gargarizans

(2016) F. Gao et al.   GENETICS AND MOLECULAR RESEARCH

Peptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer

(2016) Carolina Proaño-Bolaños et al.   Journal of Proteomics

Molecular mechanisms of LL-37-induced receptor activation: An overview

(2016) Eddy-Tim Verjans et al.   PEPTIDES

In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents

(2016) Ann M. Czyzewski et al.   PLoS One

The first anionic defensin from amphibians

(2015) Lin Wei et al.   AMINO ACIDS

The Amyloid Fibril-Forming Properties of the Amphibian Antimicrobial Peptide Uperin 3.5

(2015) Antonio N. Calabrese et al.   CHEMBIOCHEM

The Chemistry and Biological Activities of Peptides from Amphibian Skin Secretions

(2015) Xueqing Xu et al.   CHEMICAL REVIEWS

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

Fighting microbial infections: A lesson from amphibian skin-derived esculentin-1 peptides

(2015) Maria Luisa Mangoni et al.   PEPTIDES

Inhibition of HIV infection by caerin 1 antimicrobial peptides

(2015) Scott VanCompernolle et al.   PEPTIDES

Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts

(2014) Lars Erik Uggerhøj et al.   CHEMBIOCHEM

Ternary Nylon-3 Copolymers as Host-Defense Peptide Mimics: Beyond Hydrophobic and Cationic Subunits

(2014) Saswata Chakraborty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A family of antimicrobial and immunomodulatory peptides related to the frenatins from skin secretions of the Orinoco lime frog Sphaenorhynchus lacteus (Hylidae)

(2014) J. Michael Conlon et al.   PEPTIDES

Host defense peptides: front-line immunomodulators

(2014) Sarah C. Mansour et al.   TRENDS IN IMMUNOLOGY

Antimicrobial peptides: a new class of antimalarial drugs?

(2014) Nuno Vale et al.   Frontiers in Pharmacology

Different Expression Profiles of Bioactive Peptides inPelophylax nigromaculatusfrom Distinct Regions

(2013) Yuzhu SONG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Structure and Function of a Potent Lipopolysaccharide-Binding Antimicrobial and Anti-inflammatory Peptide

(2013) Lin Wei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300

(2012) Joseph Menousek et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Ab Initio Design of Potent Anti-MRSA Peptides Based on Database Filtering Technology

(2012) Biswajit Mishra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The hymenochirins: A family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae)

(2012) Milena Mechkarska et al.   PEPTIDES

The Importance of Amino Acid Composition in Natural AMPs: An Evolutional, Structural, and Functional Perspective

(2012) Biswajit Mishra et al.   Frontiers in Immunology

Amphibian cathelicidin fills the evolutionary gap of cathelicidin in vertebrate

(2011) Xue Hao et al.   AMINO ACIDS

Decoding the Functional Roles of Cationic Side Chains of the Major Antimicrobial Region of Human Cathelicidin LL-37

(2011) Guangshun Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial Mechanism of Action of Arylamide Foldamers

(2011) Bruk Mensa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural diversity and species distribution of host-defense peptides in frog skin secretions

(2011) J. Michael Conlon   CELLULAR AND MOLECULAR LIFE SCIENCES

Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides

(2011) Davor Juretić et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A kinked antimicrobial peptide from Bombina maxima. I. Three-dimensional structure determined by NMR in membrane-mimicking environments

(2011) Orsolya Toke et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs

(2011) Xinwang Yang et al.   JOURNAL OF PROTEOME RESEARCH

Describing the Mechanism of Antimicrobial Peptide Action with the Interfacial Activity Model

(2010) William C. Wimley   ACS Chemical Biology

Agents from amphibians with anticancer properties

(2010) Chuang-Xin Lu et al.   ANTI-CANCER DRUGS

Anti-Pseudomonas Activity of Frog Skin Antimicrobial Peptides in a Caenorhabditis elegans Infection Model: a Plausible Mode of Action In Vitro and In Vivo

(2010) D. Uccelletti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of Novel Human Immunodeficiency Virus Type 1-Inhibitory Peptides Based on the Antimicrobial Peptide Database

(2010) G. Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Temporin-SHf, a New Type of Phe-rich and Hydrophobic Ultrashort Antimicrobial Peptide

(2010) Feten Abbassi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution NMR studies of amphibian antimicrobial peptides: Linking structure to function?

(2009) Evan F. Haney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The role of amphibian antimicrobial peptides in protection of amphibians from pathogens linked to global amphibian declines

(2009) Louise A. Rollins-Smith   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Temporins and their synergism against Gram-negative bacteria and in lipopolysaccharide detoxification

(2009) Maria Luisa Mangoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bombinins, antimicrobial peptides from Bombina species

(2009) Maurizio Simmaco et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata

(2009) Yufang Ma et al.   GENOMICS

Amphibian antimicrobial peptides and Protozoa: Lessons from parasites

(2008) Luis Rivas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antimicrobial peptide mimics for improved therapeutic properties

(2008) Shahar Rotem et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structures of Human Host Defense Cathelicidin LL-37 and Its Smallest Antimicrobial Peptide KR-12 in Lipid Micelles

(2008) Guangshun Wang   JOURNAL OF BIOLOGICAL CHEMISTRY

APD2: the updated antimicrobial peptide database and its application in peptide design

(2008) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

A proposed nomenclature for antimicrobial peptides from frogs of the genus Leptodactylus

(2008) J. Michael Conlon   PEPTIDES

The fallaxidin peptides from the skin secretion of the Eastern Dwarf Tree FrogLitoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins

(2008) Rebecca J. Jackway et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY