IMVAMUNE® and ACAM2000® Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model

Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus challenge

(2019) Andrew T. Russo et al.   VACCINE

Atypical Cowpox Virus Infection in a Series of Cats

(2018) N. Jungwirth et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments

(2018) Ryan S. Noyce et al.   PLoS One

Emergence of Monkeypox — West and Central Africa, 1970–2017

(2018) Kara N. Durski et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

A Single Vaccination of Nonhuman Primates with Highly Attenuated Smallpox Vaccine, LC16m8, Provides Long-term Protection against Monkeypox

(2017) Itoe Iizuka et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

The Role of Brincidofovir in Preparation for a Potential Smallpox Outbreak

(2017) Scott Foster et al.   Viruses-Basel

Two Distinct Clinical Courses of Human Cowpox, Germany, 2015

(2017) Ines Eder et al.   Viruses-Basel

Estimating the Size of the U.S. Population at Risk of Severe Adverse Events from Replicating Smallpox Vaccine

(2016) Ellen P. Carlin et al.   PUBLIC HEALTH NURSING

Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

(2016) Jennifer Garver et al.   Viruses-Basel

Use of Vaccinia Virus Smallpox Vaccine in Laboratory and Health Care Personnel at Risk for Occupational Exposure to Orthopoxviruses — Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2015

(2016) Brett W. Petersen et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Treatment with the Smallpox Antiviral Tecovirimat (ST-246) Alone or in Combination with ACAM2000 Vaccination Is Effective as a Postsymptomatic Therapy for Monkeypox Virus Infection

(2015) Aklile Berhanu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lessons from a modern review of the smallpox eradication files

(2015) Wolfram G Metzger et al.   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Postchallenge Administration of Brincidofovir Protects Healthy and Immune-Deficient Mice Reconstituted with Limited Numbers of T Cells from Lethal Challenge with IHD-J-Luc Vaccinia Virus

(2015) Marina Zaitseva et al.   JOURNAL OF VIROLOGY

Sequence of Pathogenic Events in Cynomolgus Macaques Infected with Aerosolized Monkeypox Virus

(2015) J. A. Tree et al.   JOURNAL OF VIROLOGY

Evaluating anti-Orthopoxvirus antibodies in individuals from Brazilian rural areas prior to the bovine vaccinia era

(2015) Poliana de Oliveira Figueiredo et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Human Infection with a Zoonotic Orthopoxvirus in the Country of Georgia

(2015) Neil M. Vora et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccination-Related Side Effects, Humoral Immunity, and Adverse Events during the Civilian Smallpox Vaccination Campaign, Arkansas, 2003

(2015) Dirk Haselow   PUBLIC HEALTH NURSING

Using the Ground Squirrel (Marmota bobak) as an Animal Model to Assess Monkeypox Drug Efficacy

(2015) A. A. Sergeev et al.   Transboundary and Emerging Diseases

Small particle aerosol inoculation of cowpox Brighton Red in rhesus monkeys results in a severe respiratory disease

(2015) Reed F. Johnson et al.   VIROLOGY

Further Assessment of Monkeypox Virus Infection in Gambian Pouched Rats (Cricetomys gambianus) Using In Vivo Bioluminescent Imaging

(2015) Elizabeth A. Falendysz et al.   PLoS Neglected Tropical Diseases

Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

(2015) Christina L. Hutson et al.   Biomed Research International

Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial

(2015) E. T. Overton et al.   Open Forum Infectious Diseases

Susceptibility of Marmosets (Callithrix jacchus) to Monkeypox Virus: A Low Dose Prospective Model for Monkeypox and Smallpox Disease

(2015) Eric M. Mucker et al.   PLoS One

Co-administration of the broad-spectrum antiviral, brincidofovir (CMX001), with smallpox vaccine does not compromise vaccine protection in mice challenged with ectromelia virus

(2014) Scott Parker et al.   ANTIVIRAL RESEARCH

Smallpox vaccines: New formulations and revised strategies for vaccination

(2014) Nir Paran et al.   Human vaccines & immunotherapeutics

Rapid Expansion of CD8+ T Cells in Wild-Type and Type I Interferon Receptor-Deficient Mice Correlates with Protection after Low-Dose Emergency Immunization with Modified Vaccinia Virus Ankara

(2014) A. Volz et al.   JOURNAL OF VIROLOGY

Assessment of the Protective Effect of Imvamune and Acam2000 Vaccines against Aerosolized Monkeypox Virus in Cynomolgus Macaques

(2013) G. J. Hatch et al.   JOURNAL OF VIROLOGY

The effects of post-exposure smallpox vaccination on clinical disease presentation: Addressing the data gaps between historical epidemiology and modern surrogate model data

(2013) M. Shannon Keckler et al.   VACCINE

Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging

(2013) Jeffrey L. Americo et al.   VIROLOGY

Analysis of Variola and Vaccinia Virus Neutralization Assays for Smallpox Vaccines

(2012) Christine M. Hughes et al.   Clinical and Vaccine Immunology

Humoral Immunity to Smallpox Vaccines and Monkeypox Virus Challenge: Proteomic Assessment and Clinical Correlations

(2012) M. B. Townsend et al.   JOURNAL OF VIROLOGY

Side-by-Side Comparison of Gene-Based Smallpox Vaccine with MVA in Nonhuman Primates

(2012) Joseph W. Golden et al.   PLoS One

Outbreaks of human monkeypox after cessation of smallpox vaccination

(2012) Mary G. Reynolds et al.   TRENDS IN MICROBIOLOGY

Mucosal Immunization Induces a Higher Level of Lasting Neutralizing Antibody Response in Mice by a Replication-Competent Smallpox Vaccine: Vaccinia Tiantan Strain

(2011) Bin Lu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Establishment of the Black-Tailed Prairie Dog (Cynomys ludovicianus) as a Novel Animal Model for Comparing Smallpox Vaccines Administered Preexposure in both High- and Low-Dose Monkeypox Virus Challenges

(2011) M. S. Keckler et al.   JOURNAL OF VIROLOGY

Effective Antiviral Treatment of Systemic Orthopoxvirus Disease: ST-246 Treatment of Prairie Dogs Infected with Monkeypox Virus

(2011) S. K. Smith et al.   JOURNAL OF VIROLOGY

Measurement of antibody responses to Modified Vaccinia virus Ankara (MVA) and Dryvax® using proteome microarrays and development of recombinant protein ELISAs

(2011) Gary Hermanson et al.   VACCINE

Cowpox virus infection of cynomolgus macaques as a model of hemorrhagic smallpox

(2011) Reed F. Johnson et al.   VIROLOGY

Self-reported adverse health events following smallpox vaccination in a large prospective study of US military service members

(2010) Timothy S. Wells et al.   Human vaccines & immunotherapeutics

Rabbitpox: a model of airborne transmission of smallpox

(2010) A. Nalca et al.   JOURNAL OF GENERAL VIROLOGY

A Mouse Model of Lethal Infection for Evaluating Prophylactics and Therapeutics against Monkeypox Virus

(2010) J. Stabenow et al.   JOURNAL OF VIROLOGY

Identification of Wild-Derived Inbred Mouse Strains Highly Susceptible to Monkeypox Virus Infection for Use as Small Animal Models

(2010) J. L. Americo et al.   JOURNAL OF VIROLOGY

Immune Requirements of Post-Exposure Immunization with Modified Vaccinia Ankara of Lethally Infected Mice

(2010) Henning Lauterbach et al.   PLoS One

A Novel Highly Reproducible and Lethal Nonhuman Primate Model for Orthopox Virus Infection

(2010) Marit Kramski et al.   PLoS One

Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo

(2010) A. W. Rimoin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal Models of Orthopoxvirus Infection

(2010) J. L. Chapman et al.   VETERINARY PATHOLOGY

Dosage comparison of Congo Basin and West African strains of monkeypox virus using a prairie dog animal model of systemic orthopoxvirus disease

(2010) Christina L. Hutson et al.   VIROLOGY

Monkeypox Virus Infections in Small Animal Models for Evaluation of Anti-Poxvirus Agents

(2010) Christina L. Hutson et al.   Viruses-Basel

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

(2010) Scott Parker et al.   Viruses-Basel

A prairie dog animal model of systemic orthopoxvirus disease using West African and Congo Basin strains of monkeypox virus

(2009) C. L. Hutson et al.   JOURNAL OF GENERAL VIROLOGY

Immunogenicity of recombinant Modified Vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys

(2009) Lauren E. Grandpre et al.   VACCINE

One time intranasal vaccination with a modified vaccinia Tiantan strain MVTTZCI protects animals against pathogenic viral challenge

(2009) Wenbo Yu et al.   VACCINE

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

(2008) Christofer Samuelsson et al.   JOURNAL OF CLINICAL INVESTIGATION

Postexposure Immunization with Modified Vaccinia Virus Ankara or Conventional Lister Vaccine Provides Solid Protection in a Murine Model of Human Smallpox

(2008) Nir Paran et al.   JOURNAL OF INFECTIOUS DISEASES

A rapid, high-throughput vaccinia virus neutralization assay for testing smallpox vaccine efficacy based on detection of green fluorescent protein

(2008) Matthew C. Johnson et al.   JOURNAL OF VIROLOGICAL METHODS

Rapid protection in a monkeypox model by a single injection of a replication-deficient vaccinia virus

(2008) P. L. Earl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA